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Matrix information:
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ADAN-name: 1FYR2.PDB
Scoring matrix: 1FYR2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: yVNV
Foldx wt ligand score: 1.3
Foldx random average score for Homo sapiens: 13.448 Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
Proteins belonging to other specie: 6
Nš of interactions described: 157
Interactions with other species: 28
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 32230
Total fragments: 13709061
Proteins after random average filtering: 32226
Total fragments: 7785391
Proteins after disorder filtering: 25689
Total fragments: 665746
Proteins after pattern filtering: 12071
Total fragments: 52691
Proteins after MINT filtering: 8
Total fragments: 48
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
yVNV |
1.30
|
-12.89 |
0.00 |
| Best peptides |
yLNM |
0.00
|
-12.01 |
0.88 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P27986 |
GYNE |
9.15
|
-5.63 |
7.26 |
|
NGYN |
12.49
|
-1.67 |
11.22 |
| Q07889 |
KKYS |
11.01
|
-3.77 |
9.12 |
|
KTYK |
11.18
|
-3.43 |
9.46 |
|
KAYS |
11.28
|
7.26 |
20.15 |
| Q9UKW4 |
VDYS |
11.23
|
-0.82 |
12.07 |
|
RNYS |
11.84
|
-3.19 |
9.70 |
| Q07890 |
KTYK |
11.18
|
-3.43 |
9.46 |
|
TYKR |
12.43
|
-1.36 |
11.53 |
| Q9UQC2 |
SVYI |
10.33
|
2.31 |
15.20 |
|
ENYV |
10.36
|
-4.43 |
8.46 |
|
DVYT |
10.71
|
-5.80 |
7.09 |
| Q6S383 |
KAYS |
11.28
|
7.26 |
20.15 |
|
RRYA |
11.64
|
-4.24 |
8.65 |
|
SSYS |
12.38
|
-2.84 |
10.05 |
| Q13905 |
YDNI |
6.84
|
-10.49 |
2.40 |
|
QYDN |
11.45
|
-3.59 |
9.30 |
|
SQYD |
11.73
|
-4.45 |
8.44 |
| Q13480 |
LYNL |
6.05
|
-7.76 |
5.13 |
|
ELYV |
9.18
|
-5.47 |
7.42 |
|
YVFN |
10.06
|
-2.56 |
10.33 |
|
