ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1FYR2.PDB
Scoring matrix: 1FYR2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: yVNV
Foldx wt ligand score: 1.3
Foldx random average score for Homo sapiens: 13.448

Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
 Proteins belonging to other specie: 6
Nš of interactions described: 157
 Interactions with other species: 28

Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 32230
 Total fragments: 13709061
Proteins after random average filtering: 32226
 Total fragments: 7785391
Proteins after disorder filtering: 25689
 Total fragments: 665746
Proteins after pattern filtering: 12071
 Total fragments: 52691
Proteins after MINT filtering: 8
 Total fragments: 48


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

yVNV

1.30

-12.89

0.00

Best peptides

yLNM

0.00

-12.01

0.88

         
Interactors      
P27986

GYNE

9.15

-5.63

7.26

NGYN

12.49

-1.67

11.22

Q07889

KKYS

11.01

-3.77

9.12

KTYK

11.18

-3.43

9.46

KAYS

11.28

7.26

20.15

Q9UKW4

VDYS

11.23

-0.82

12.07

RNYS

11.84

-3.19

9.70

Q07890

KTYK

11.18

-3.43

9.46

TYKR

12.43

-1.36

11.53

Q9UQC2

SVYI

10.33

2.31

15.20

ENYV

10.36

-4.43

8.46

DVYT

10.71

-5.80

7.09

Q6S383

KAYS

11.28

7.26

20.15

RRYA

11.64

-4.24

8.65

SSYS

12.38

-2.84

10.05

Q13905

YDNI

6.84

-10.49

2.40

QYDN

11.45

-3.59

9.30

SQYD

11.73

-4.45

8.44

Q13480

LYNL

6.05

-7.76

5.13

ELYV

9.18

-5.47

7.42

YVFN

10.06

-2.56

10.33

 


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