Matrix information:
(Help) ADAN-name: 1FYR2.PDB Scoring matrix: 1FYR2_mat Uniprot code: P62993 Genome source: Homo sapiens Wild-type ligand: yVNV Foldx wt ligand score: 1.3 Foldx random average score for Homo sapiens: 13.448 Available information for P62993 in MINT (Nov 2008): Nš of interacting proteins: 64 Proteins belonging to other specie: 6 Nš of interactions described: 157 Interactions with other species: 28
Genome scanning information:
Subcellular location: True Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831 Proteins considered as fragments or having non-standard amino acids: 22829 Total scanned proteins: 32230 Total fragments: 13709061 Proteins after random average filtering: 32226 Total fragments: 7785391 Proteins after disorder filtering: 25689 Total fragments: 665746 Proteins after pattern filtering: 12071 Total fragments: 52691 Proteins after MINT filtering: 8 Total fragments: 48
Prediction of know targets:
Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
Reference wt |
yVNV |
1.30
|
-12.89 |
0.00 |
Best peptides |
yLNM |
0.00
|
-12.01 |
0.88 |
|
|
|
|
|
Interactors |
|
|
|
|
P27986 |
GYNE |
9.15
|
-5.63 |
7.26 |
|
NGYN |
12.49
|
-1.67 |
11.22 |
Q07889 |
KKYS |
11.01
|
-3.77 |
9.12 |
|
KTYK |
11.18
|
-3.43 |
9.46 |
|
KAYS |
11.28
|
7.26 |
20.15 |
Q9UKW4 |
VDYS |
11.23
|
-0.82 |
12.07 |
|
RNYS |
11.84
|
-3.19 |
9.70 |
Q07890 |
KTYK |
11.18
|
-3.43 |
9.46 |
|
TYKR |
12.43
|
-1.36 |
11.53 |
Q9UQC2 |
SVYI |
10.33
|
2.31 |
15.20 |
|
ENYV |
10.36
|
-4.43 |
8.46 |
|
DVYT |
10.71
|
-5.80 |
7.09 |
Q6S383 |
KAYS |
11.28
|
7.26 |
20.15 |
|
RRYA |
11.64
|
-4.24 |
8.65 |
|
SSYS |
12.38
|
-2.84 |
10.05 |
Q13905 |
YDNI |
6.84
|
-10.49 |
2.40 |
|
QYDN |
11.45
|
-3.59 |
9.30 |
|
SQYD |
11.73
|
-4.45 |
8.44 |
Q13480 |
LYNL |
6.05
|
-7.76 |
5.13 |
|
ELYV |
9.18
|
-5.47 |
7.42 |
|
YVFN |
10.06
|
-2.56 |
10.33 |
|