ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1FU52.PDB
Scoring matrix: 1FU52_mat
Uniprot code: Q63787
Genome source: Rattus norvegicus
Wild-type ligand: EEEyMPMEDLyLDIL
Foldx wt ligand score: 59.45
Foldx random average score for Rattus norvegicus: 41.063

Available information for Q63787 in MINT (Nov 2008):
Nš of interacting proteins: 9
 Proteins belonging to other specie: 0
Nš of interactions described: 13
 Interactions with other species: 0

Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 1
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11953
 Total fragments: 5484524
Proteins after random average filtering: 11946
 Total fragments: 2827013
Proteins after disorder filtering: 7897
 Total fragments: 177528
Proteins after pattern filtering: 4150
 Total fragments: 33449
Proteins after MINT filtering: 3
 Total fragments: 111


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

EEEyMPMEDLyLDIL

59.45

38.59

0.00

Best peptides

PGKGsMGGGLTyGKK

0.00

45.75

7.16

         
Interactors      
P35570

TSSDSLGGGYCGARP

18.36

13.81

-24.78

PPGGGSGGRLPGYRH

19.79

15.57

-23.02

SLGGGYCGARPESSV

20.80

14.03

-24.56

O08724

KGLGRAPGLSSGSYR

23.05

21.88

-16.71

GSAPSYRGPDLGGDY

28.87

23.02

-15.57

EVPGAAPGNSPHSYA

32.63

21.40

-17.19

P62813

PTATSYTPNLARGDP

36.22

18.08

-20.51

YAPTATSYTPNLARG

40.95

19.06

-19.53

 


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