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Matrix information:
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ADAN-name: 1D5G2.PDB
Scoring matrix: 1D5G2_mat
Uniprot code: Q12923
Genome source: Homo sapiens
Wild-type ligand: NEQVSAV
Foldx wt ligand score: 7.84
Foldx random average score for Homo sapiens: 7.696 Available information for Q12923 in MINT (Nov 2008):
Nš of interacting proteins: 8
Proteins belonging to other specie: 2
Nš of interactions described: 22
Interactions with other species: 3
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18329481
Proteins after random average filtering: 40310
Total fragments: 9011838
Proteins after disorder filtering: 30777
Total fragments: 880213
Proteins after pattern filtering: 19987
Total fragments: 66160
Proteins after MINT filtering: 4
Total fragments: 12
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
NEQVSAV |
7.84
|
3.38 |
0.00 |
| Best peptides |
EMDDEML |
0.00
|
-1.68 |
-5.06 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P25445 |
LGIWTLL |
7.38
|
-2.37 |
-5.75 |
| Q9HB19 |
RPGSSSL |
5.36
|
-0.59 |
-3.97 |
|
SGPNSIL |
6.37
|
-2.67 |
-6.05 |
|
VLPSSRI |
7.62
|
-1.20 |
-4.58 |
| P08138 |
GGLYSSL |
5.47
|
-0.62 |
-4.00 |
|
SDSGISV |
7.04
|
-1.21 |
-4.59 |
|
LHSDSGI |
7.43
|
-0.12 |
-3.50 |
| Q16513 |
TKLDFDL |
2.91
|
-4.95 |
-8.33 |
|
PPRASSL |
5.64
|
-0.83 |
-4.21 |
|
DTPQSGL |
6.69
|
-0.70 |
-4.08 |
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