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Matrix information:
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ADAN-name: 1D4T2.PDB
Scoring matrix: 1D4T2_mat
Uniprot code: O60880
Genome source: Homo sapiens
Wild-type ligand: KSLTIYAQVQK
Foldx wt ligand score: 9.12
Foldx random average score for Homo sapiens: 16.191 Available information for O60880 in MINT (Nov 2008):
Nš of interacting proteins: 16
Proteins belonging to other specie: 2
Nš of interactions described: 24
Interactions with other species: 2
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 7744
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 40317
Total fragments: 18170597
Proteins after random average filtering: 40289
Total fragments: 10138051
Proteins after disorder filtering: 26035
Total fragments: 275346
Proteins after pattern filtering: 11479
Total fragments: 44641
Proteins after MINT filtering: 6
Total fragments: 46
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KSLTIYAQVQK |
9.12
|
-17.17 |
0.00 |
| Best peptides |
yyRLIMFMLyA |
0.00
|
-22.41 |
-5.24 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P00533 |
PPLMLYNPTTY |
9.25
|
-13.99 |
3.18 |
|
DYQQDFFPKEA |
11.58
|
-14.77 |
2.40 |
|
PAGSVQNPVYH |
12.28
|
-11.72 |
5.45 |
| Q16288 |
HYNNGNYTLIA |
11.93
|
-13.61 |
3.56 |
|
THYNNGNYTLI |
13.64
|
-11.98 |
5.19 |
|
NKPTHYNNGNY |
14.51
|
-10.86 |
6.31 |
| Q14155 |
AYHTLPHPSHH |
13.07
|
-13.18 |
3.99 |
|
PAPLTPAYHTL |
15.44
|
-10.89 |
6.28 |
|
APLTPAYHTLP |
15.91
|
-12.11 |
5.06 |
| P21860 |
EDYEYMNRQRD |
8.70
|
-18.37 |
-1.20 |
|
YMPMNQGNLGE |
11.47
|
-12.76 |
4.41 |
|
YEYMNRQRDGG |
12.59
|
-14.04 |
3.13 |
| O15117 |
KQLDMGDEVYD |
10.79
|
-14.81 |
2.36 |
|
MGDEVYDDVDT |
13.62
|
-13.31 |
3.86 |
|
DDDIYDGIEEE |
14.98
|
-13.39 |
3.78 |
| P06241 |
PNYNNFHAAGG |
12.99
|
-12.51 |
4.66 |
|
SIPNYNNFHAA |
13.58
|
-11.49 |
5.68 |
|
GVTSIPNYNNF |
13.76
|
-11.72 |
5.45 |
|
