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Matrix information:
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ADAN-name: 1BMB2.PDB
Scoring matrix: 1BMB2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: KPFyVNVEF
Foldx wt ligand score: 5.57
Foldx random average score for Homo sapiens: 18.796 Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
Proteins belonging to other specie: 6
Nš of interactions described: 157
Interactions with other species: 28
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 15831
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 32230
Total fragments: 13547926
Proteins after random average filtering: 32211
Total fragments: 6832156
Proteins after disorder filtering: 23556
Total fragments: 442771
Proteins after pattern filtering: 11139
Total fragments: 61071
Proteins after MINT filtering: 7
Total fragments: 56
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KPFyVNVEF |
5.57
|
-17.97 |
0.00 |
| Best peptides |
MyDyyNLss |
0.00
|
-18.89 |
-0.92 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P27986 |
GYNETTGER |
14.98
|
-2.75 |
15.22 |
|
NGYNETTGE |
18.20
|
-3.67 |
14.30 |
| Q07889 |
YKREHTHPS |
15.93
|
-3.48 |
14.49 |
|
KYSYPLKSP |
16.53
|
-6.80 |
11.17 |
|
KKYSYPLKS |
17.29
|
-3.65 |
14.32 |
| Q07890 |
KLPPKTYKR |
17.80
|
-5.63 |
12.34 |
| Q9UQC2 |
GDSEENYVP |
11.85
|
-6.59 |
11.38 |
|
TNSEDNYVP |
12.69
|
-6.07 |
11.90 |
|
ETDNEDVYT |
14.67
|
-5.08 |
12.89 |
| Q6S383 |
YSPYSVSGS |
17.20
|
-3.87 |
14.10 |
|
YYSPYSVSG |
17.81
|
-3.38 |
14.59 |
|
YSDPSTGEP |
18.20
|
-5.45 |
12.52 |
| Q13905 |
PSQYDNISG |
13.86
|
-8.91 |
9.06 |
|
QYDNISGED |
16.57
|
-3.09 |
14.88 |
|
SQYDNISGE |
16.74
|
-6.06 |
11.91 |
| Q13480 |
HDSEENYVP |
12.05
|
-7.08 |
10.89 |
|
PPPYQLINV |
13.15
|
-9.63 |
8.34 |
|
ELYVFNTPS |
13.95
|
-9.89 |
8.08 |
|
