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Matrix information:
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ADAN-name: 1BF52.PDB
Scoring matrix: 1BF52_mat
Uniprot code: P42224
Genome source: Homo sapiens
Wild-type ligand: GYIKTELISV
Foldx wt ligand score: 5.45
Foldx random average score for Homo sapiens: 5.300 Available information for P42224 in MINT (Nov 2008):
Nš of interacting proteins: 21
Proteins belonging to other specie: 3
Nš of interactions described: 50
Interactions with other species: 9
Genome scanning information:
Subcellular location: True
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 4117
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 43944
Total fragments: 20329743
Proteins after random average filtering: 43930
Total fragments: 10600473
Proteins after disorder filtering: 33028
Total fragments: 966826
Proteins after pattern filtering: 16772
Total fragments: 113786
Proteins after MINT filtering: 9
Total fragments: 75
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
GYIKTELISV |
5.45
|
0.34 |
0.00 |
| Best peptides |
RRpRGHKMKG |
0.00
|
6.58 |
6.24 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P19438 |
QGKYIHPQNN |
4.14
|
-1.04 |
-1.38 |
|
PQGKYIHPQN |
4.21
|
-0.81 |
-1.15 |
|
YNDCPGPGQD |
4.39
|
-0.87 |
-1.21 |
| O75925 |
MTPMPYDLQG |
3.55
|
-0.76 |
-1.10 |
|
LTYDGHPASS |
3.71
|
0.04 |
-0.30 |
|
GYLPPTKNGV |
3.78
|
1.68 |
1.34 |
| Q8N6P7 |
WPPSYGVCME |
3.56
|
-1.04 |
-1.38 |
|
SPLSYAPNAA |
3.86
|
1.26 |
0.92 |
|
PPSYGVCMEG |
3.97
|
-1.01 |
-1.35 |
| P04626 |
NPEYLTPQGG |
3.95
|
0.60 |
0.26 |
|
PEYLTPQGGA |
4.12
|
1.55 |
1.21 |
|
FDNLYYWDQD |
4.15
|
-0.41 |
-0.75 |
| Q92793 |
QGPGGYPPAM |
3.93
|
0.07 |
-0.27 |
|
GMPYPTPAMQ |
4.26
|
-1.03 |
-1.37 |
|
CPPSEGDDYI |
4.96
|
-0.10 |
-0.44 |
| P35368 |
SPGYLGRGAP |
4.42
|
-1.02 |
-1.36 |
|
SPSPGYLGRG |
4.47
|
-2.05 |
-2.39 |
|
ASPSPGYLGR |
4.55
|
1.26 |
0.92 |
| P29597 |
AVYRCGPPGT |
4.01
|
1.10 |
0.76 |
|
REPAVYRCGP |
4.03
|
-0.87 |
-1.21 |
|
YCYDPTNDGT |
4.37
|
2.59 |
2.25 |
| P48551 |
DYSSTEGSGG |
4.42
|
1.22 |
0.88 |
|
EEDYSSTEGS |
4.80
|
2.15 |
1.81 |
|
YSSTEGSGGR |
4.86
|
2.20 |
1.86 |
| P38398 |
DRWYMHSCSG |
3.84
|
-0.17 |
-0.51 |
|
PSLDDRWYMH |
4.14
|
-1.72 |
-2.06 |
|
DDRWYMHSCS |
4.17
|
-1.64 |
-1.98 |
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