ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1BE92.PDB
Scoring matrix: 1BE92_mat
Uniprot code: P31016
Genome source: Rattus norvegicus
Wild-type ligand: KQTSV
Foldx wt ligand score: 2.83
Foldx random average score for Rattus norvegicus: 9.499

Available information for P31016 in MINT (Nov 2008):
Nš of interacting proteins: 55
 Proteins belonging to other specie: 18
Nš of interactions described: 141
 Interactions with other species: 34

Genome scanning information:
Subcellular location: True
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 2291
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 9663
 Total fragments: 4597720
Proteins after random average filtering: 9662
 Total fragments: 2886881
Proteins after disorder filtering: 7763
 Total fragments: 269993
Proteins after pattern filtering: 5944
 Total fragments: 29309
Proteins after MINT filtering: 28
 Total fragments: 278


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

KQTSV

2.83

-11.26

0.00

Best peptides

PLTFV

0.00

-10.18

1.08

         
Interactors      
Q6IN36

PSTSV

3.92

-8.37

2.89

PPTFA

4.64

-10.42

0.84

GLFQA

5.42

-8.88

2.38

Q8R4T5

PLLAA

5.41

-8.76

2.50

AETPA

5.69

-7.40

3.86

TPASV

6.07

-7.16

4.10

Q63226

TMSSI

4.98

-9.92

1.34

FRSPI

5.63

-9.06

2.20

PVTGL

7.59

-10.20

1.06

Q62765

TITMI

2.52

-11.67

-0.41

KPVMV

3.57

-12.20

-0.94

VMVYI

4.05

-11.95

-0.69

P15385

GYSSV

5.08

-8.90

2.36

NDTSA

7.96

-8.25

3.01

HCSDL

8.26

-8.31

2.95

Q71RJ2

DASPV

4.69

-7.56

3.70

SPVGV

6.51

-6.85

4.41

Q9WV48

GLFDI

3.51

-11.22

0.04

APVFV

3.68

-10.08

1.18

LPLLV

4.01

-11.28

-0.02

Q8K430

PTLSV

4.09

-10.82

0.44

GSSSL

9.21

-5.14

6.12

Q9QX19

GRLPA

7.19

-8.11

3.15

ASSPA

7.78

-5.72

5.54

Q00960

NKSSV

4.75

-9.31

1.95

KPLDI

4.99

-9.59

1.67

YSSTV

5.50

-8.21

3.05

Q9JJ40

APAPI

5.87

-7.38

3.88

KEAPA

6.64

-6.67

4.59

APLEA

7.29

-6.32

4.94

P11506

PGSPI

4.54

-7.99

3.27

NNSAI

4.85

-8.58

2.68

IDSGI

5.97

-7.02

4.24

P97924

YQFRV

3.71

-10.68

0.58

PPMKI

4.20

-12.06

-0.80

PPLKI

4.33

-12.06

-0.80

P30937

MNTPA

5.31

-7.32

3.94

PGINA

6.71

-7.91

3.35

ATLPL

8.67

-6.06

5.20

P05696

HKFKI

4.76

-10.65

0.61

PYVKL

8.79

-10.21

1.05

Q9WUL3

GSYMV

3.77

-10.95

0.31

SYMVV

5.66

-8.99

2.27

ARLQL

7.94

-10.95

0.31

P20595

PQFHL

5.59

-8.87

2.39

Q9QUH6

DLFYV

1.55

-13.25

-1.99

PQITI

3.99

-11.33

-0.07

LSTGV

5.01

-7.34

3.92

P70587

PETEV

2.14

-11.86

-0.60

KGIFV

2.73

-12.33

-1.07

DNSDI

3.46

-9.64

1.62

Q9Z1T4

LNAPV

3.61

-9.84

1.42

PTSSV

4.08

-9.00

2.26

QDLYI

4.60

-10.64

0.62

Q62936

PGIFI

3.03

-12.44

-1.18

PSLSV

4.48

-10.25

1.01

FGSCV

5.18

-8.53

2.73

P97836

LLSPV

2.95

-9.51

1.75

TPSGV

5.92

-6.86

4.40

ARSNA

6.95

-5.27

5.99

P35439

GNTNI

3.03

-12.51

-1.25

TPTPV

4.91

-8.65

2.61

Q63622

PGIFI

3.03

-12.44

-1.18

FGSCV

5.18

-8.53

2.73

LGFSI

5.41

-9.12

2.14

Q62868

DSSSI

5.76

-8.45

2.81

P29476

WNTHV

1.09

-12.91

-1.65

PCILV

2.65

-11.92

-0.66

KTIRV

4.41

-12.10

-0.84

Q00959

PSFHL

7.09

-7.64

3.62

CLSNL

7.32

-10.77

0.49

SKSLL

7.78

-10.98

0.28

Q9WVI4

PLSKL

5.90

-10.28

0.98

PGSRA

6.44

-4.82

6.44

 


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