ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1AWJ2.PDB
Scoring matrix: 1AWJ2_mat
Uniprot code: Q03526
Genome source: Mus musculus
Wild-type ligand: KKPLPPTPEDN
Foldx wt ligand score: 7.47
Foldx random average score for Mus musculus: 6.737

Available information for Q03526 in MINT (Nov 2008):
Nš of interacting proteins: 3
 Proteins belonging to other specie: 1
Nš of interactions described: 4
 Interactions with other species: 2

Genome scanning information:
Subcellular location: True
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 6057
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 38389
 Total fragments: 17390865
Proteins after random average filtering: 38383
 Total fragments: 9250282
Proteins after disorder filtering: 26950
 Total fragments: 646459
Proteins after pattern filtering: 18621
 Total fragments: 148865
Proteins after MINT filtering: 2
 Total fragments: 21


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

KKPLPPTPEDN

7.47

0.48

0.00

Best peptides

RRGMQHEMGMI

0.00

15.42

14.94

         
Interactors      
O35716

APVRPRPCPAV

4.29

0.65

0.17

AVPAPAPGDTH

4.63

0.92

0.44

SSPAAPVRPRP

5.73

-2.22

-2.70

Q9QUN3

RAGKKPATPLK

4.00

1.42

0.94

LPAAPSPLPRA

4.38

-0.13

-0.61

VHQKPVPLPRF

4.82

-0.51

-0.99

 


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