ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SHO1_2VKN-26.PDB
Scoring matrix: SHO1_2VKN-26_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.4
Foldx random average score for Saccharomyces cerevisiae: 14.644

Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
 Proteins belonging to other specie: 0
Nš of interactions described: 68
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7178
 Total fragments: 1387264
Proteins after disorder filtering: 4338
 Total fragments: 65836
Proteins after pattern filtering: 2192
 Total fragments: 15150
Proteins after MINT filtering: 33
 Total fragments: 480

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.40

-2.10

0.00

Best peptides

DDRPRRFPR

0.00

-13.68

-11.58

         
Interactors      
P11710

PLPLTPNSK

13.72

-6.98

-4.88

SKPLPLTPN

13.95

-6.04

-3.94

KPLPLTPNS

14.09

-7.85

-5.75

Q06604

PPLPTRRDH

7.26

-8.93

-6.83

EEKPLLPTR

7.50

-9.95

-7.85

GPRMPSRGR

8.12

-6.62

-4.52

P24814

LHPPDIHPN

10.12

-9.10

-7.00

HPPDIHPNL

13.18

-6.17

-4.07

RLHPPDIHP

13.56

-4.71

-2.61

P40073

GYPQQQPSH

13.87

-6.13

-4.03

DGYPQQQPS

14.15

-6.20

-4.10

P24583

PPQPRKHDK

8.66

-9.11

-7.01

NAPLPPQPR

9.40

-8.73

-6.63

PLPPQPRKH

9.52

-9.11

-7.01

Q06412

ERRPPPPPP

8.86

-9.45

-7.35

SPNSPKSPR

10.09

-3.96

-1.86

RRPPPPPPL

10.24

-8.83

-6.73

P40036

IELPPLSPK

11.95

-6.28

-4.18

PTTPGIRSG

12.29

-5.64

-3.54

SLPTTPGIR

12.58

-6.75

-4.65

P18494

RSVVPILPK

11.89

-7.72

-5.62

VPILPKPSP

12.44

-7.77

-5.67

PILPKPSPN

12.47

-6.70

-4.60

P40055

DIPDVKPDV

11.48

-6.48

-4.38

SDIPDVKPD

14.28

-6.67

-4.57

IPDVKPDVK

14.28

-6.31

-4.21

P09620

SNPISKPSI

10.62

-5.90

-3.80

PDPSNIPQM

11.32

-7.78

-5.68

PSNIPQMHA

13.31

-5.20

-3.10

P13186

EPLPEREPP

9.50

-10.80

-8.70

KAPSYVPNR

9.56

-7.54

-5.44

IPMSPNYGN

11.22

-6.79

-4.69

P04051

DRSLPHFPK

9.85

-7.01

-4.91

RSLPHFPKN

11.67

-8.56

-6.46

LPHFPKNSK

12.06

-5.26

-3.16

P38753

PVMPPQRQS

10.77

-7.59

-5.49

NTPVMPPQR

10.88

-9.05

-6.95

SNLPIQHPT

12.72

-7.10

-5.00

Q08229

DYNPTIPPR

7.15

-9.58

-7.48

NPTIPPRSK

11.80

-4.96

-2.86

LTRPLPSTP

12.18

-6.53

-4.43

P40020

VLPPLPFPL

9.30

-7.97

-5.87

SEEPTSPTR

9.36

-7.86

-5.76

LTPESPLNR

10.67

-8.08

-5.98

Q00246

DEKNLPRLP

10.54

-5.63

-3.53

EKNLPRLPT

11.58

-9.91

-7.81

KNLPRLPTP

12.02

-9.04

-6.94

P32448

TDSPQLPSK

11.84

-7.73

-5.63

PQLPSKDKS

12.36

-6.47

-4.37

SPQLPSKDK

12.57

-6.33

-4.23

Q04439

SSKPKEPMF

9.71

-8.36

-6.26

PSPPTAATR

10.23

-6.97

-4.87

SKKPAPPPP

10.33

-8.82

-6.72

P35197

TPAKPPQER

8.79

-6.71

-4.61

QSRPDHLPP

11.12

-8.91

-6.81

SRPDHLPPS

12.21

-6.90

-4.80

Q12446

PPPPPRASR

6.25

-11.65

-9.55

PPPPPRRGP

7.74

-9.09

-6.99

PAPPPPPHR

8.09

-9.78

-7.68

P08018

DGPPPRLPS

8.72

-13.96

-11.86

PTRPNVAPH

9.92

-6.92

-4.82

STQHPTRPN

10.47

-4.49

-2.39

P53552

ALRPTGPDR

9.06

-8.68

-6.58

PTRPSKSKT

11.63

-5.06

-2.96

NTQALPQGP

13.98

-5.64

-3.54

P39969

LSPIPSPTR

10.40

-6.98

-4.88

PAQPPKSPL

10.64

-6.88

-4.78

PRRAPKPPS

10.88

-6.65

-4.55

P46674

ATRPNHFPF

6.84

-9.31

-7.21

STSPPLPSH

12.44

-7.73

-5.63

TRPNHFPFS

14.00

-5.33

-3.23

P14906

GHPDGPQST

14.29

-3.38

-1.28

Q03790

TATPSPFRP

11.48

-7.81

-5.71

PSAPQPLFM

12.41

-7.23

-5.13

PTATPSPFR

13.08

-6.12

-4.02

P40568

TPAMIPYPG

12.07

-6.64

-4.54

PAMIPYPGS

12.61

-7.24

-5.14

PTPAMIPYP

13.06

-6.35

-4.25

Q12443

PDPITVPAP

12.22

-7.70

-5.60

EIPDPITVP

13.45

-5.35

-3.25

PITVPAPTR

13.71

-6.47

-4.37

P41809

TYPTTPYPS

11.76

-6.80

-4.70

TSSPSVPVA

13.53

-6.90

-4.80

SSPSAPAAI

13.79

-4.34

-2.24

Q05080

RQKPDKPRP

9.85

-9.06

-6.96

LRQKPDKPR

9.97

-7.56

-5.46

QKPDKPRPI

10.39

-5.39

-3.29

P07248

NSPISPHKL

12.54

-6.19

-4.09

SNSPISPHK

13.02

-7.29

-5.19

LSNSPISPH

13.59

-4.26

-2.16

P53297

SLPPKPISK

9.33

-9.85

-7.75

MGMYMPFQP

9.84

-7.19

-5.09

PSMPQMMPV

9.85

-8.64

-6.54

P22147

IPPPAPHGF

9.80

-8.69

-6.59

FPPPPPMTN

10.28

-9.39

-7.29

FGQPISFPP

10.88

-7.53

-5.43

 


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