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Matrix information:
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ADAN-name: SHO1_2VKN-25.PDB
Scoring matrix: SHO1_2VKN-25_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.74
Foldx random average score for Saccharomyces cerevisiae: 14.787 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7178
Total fragments: 1486836
Proteins after disorder filtering: 4402
Total fragments: 68519
Proteins after pattern filtering: 2199
Total fragments: 13331
Proteins after MINT filtering: 36
Total fragments: 434 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAAA |
18.74
|
-1.19 |
0.00 |
| Best peptides |
RRPPRFPRR |
0.00
|
-9.87 |
-8.68 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
SKPLPLTPN |
10.75
|
-4.87 |
-3.68 |
|
PLPLTPNSK |
12.70
|
-5.99 |
-4.80 |
|
LPLTPNSKY |
13.73
|
-5.45 |
-4.26 |
| Q06604 |
SPPPLPTRR |
6.35
|
-8.60 |
-7.41 |
|
EKPLLPTRP |
7.67
|
-9.22 |
-8.03 |
|
PRMPSRGRP |
8.44
|
-5.71 |
-4.52 |
| P24814 |
RLHPPDIHP |
11.16
|
-3.77 |
-2.58 |
|
NNSTRPQMP |
11.82
|
-5.62 |
-4.43 |
|
HPPDIHPNL |
11.92
|
-5.92 |
-4.73 |
| P40073 |
GYPQQQPSH |
14.13
|
-3.99 |
-2.80 |
|
YPQQQPSHT |
14.65
|
-4.23 |
-3.04 |
| P24583 |
PLPPQPRKH |
7.80
|
-8.42 |
-7.23 |
|
APLPPQPRK |
12.15
|
-6.07 |
-4.88 |
|
NAPLPPQPR |
12.22
|
-3.93 |
-2.74 |
| Q06412 |
RRPPPPPPL |
8.14
|
-7.46 |
-6.27 |
|
PNSPKSPRD |
10.10
|
-4.87 |
-3.68 |
|
RPPPPPPLL |
10.54
|
-6.50 |
-5.31 |
| P40036 |
SLPTTPGIR |
9.39
|
-7.83 |
-6.64 |
|
ELPPLSPKS |
10.72
|
-6.04 |
-4.85 |
|
PLSPKSTVP |
13.15
|
-2.56 |
-1.37 |
| P18494 |
SRSVVPILP |
10.10
|
-4.78 |
-3.59 |
|
PKPSPNSAN |
10.63
|
-4.34 |
-3.15 |
|
SVVPILPKP |
10.92
|
-7.78 |
-6.59 |
| P40055 |
IPDVKPDVK |
11.41
|
-4.28 |
-3.09 |
|
NSDIPDVKP |
11.95
|
-3.22 |
-2.03 |
|
DIPDVKPDV |
13.74
|
-5.11 |
-3.92 |
| P09620 |
KLSNPISKP |
11.03
|
-5.37 |
-4.18 |
|
NPISKPSIH |
12.21
|
-5.53 |
-4.34 |
|
SNPISKPSI |
12.62
|
-2.82 |
-1.63 |
| P13186 |
KAPSYVPNR |
10.44
|
-3.82 |
-2.63 |
|
PLPEREPPT |
11.17
|
-7.06 |
-5.87 |
|
APSYVPNRV |
11.95
|
-4.81 |
-3.62 |
| P04051 |
RSLPHFPKN |
9.38
|
-6.16 |
-4.97 |
|
PHFPKNSKT |
11.98
|
-5.79 |
-4.60 |
|
SLPHFPKNS |
12.10
|
-5.97 |
-4.78 |
| P39083 |
LQSPATPSN |
13.19
|
-0.98 |
0.21 |
|
HLLQSPATP |
13.83
|
-5.95 |
-4.76 |
| P38753 |
NTPVMPPQR |
9.58
|
-7.05 |
-5.86 |
|
NLPIQHPTN |
10.18
|
-5.21 |
-4.02 |
|
PYPSNLPIQ |
11.63
|
-5.40 |
-4.21 |
| Q06524 |
YNPTVPNEL |
13.31
|
-5.31 |
-4.12 |
|
TWKYNPTVP |
13.53
|
-4.00 |
-2.81 |
|
WKYNPTVPN |
13.90
|
-0.92 |
0.27 |
| P40020 |
PPPLTPEKN |
9.71
|
-5.75 |
-4.56 |
|
DRPPPLTPE |
10.17
|
-5.66 |
-4.47 |
|
EEPTSPTRQ |
10.59
|
-5.84 |
-4.65 |
| Q00246 |
NLPRLPTPF |
10.67
|
-7.46 |
-6.27 |
|
KNLPRLPTP |
11.35
|
-5.72 |
-4.53 |
|
NLPESPGTL |
11.78
|
-5.24 |
-4.05 |
| P32448 |
DSPQLPSKD |
10.74
|
-5.33 |
-4.14 |
|
PQLPSKDKS |
12.21
|
-4.14 |
-2.95 |
|
PRVPTDSPQ |
13.57
|
-5.43 |
-4.24 |
| Q08229 |
YNPTIPPRS |
8.71
|
-8.14 |
-6.95 |
|
TRPLPSTPN |
11.05
|
-3.41 |
-2.22 |
|
PTIPPRSKD |
11.64
|
-5.24 |
-4.05 |
| Q04439 |
ARPSPPTAA |
9.80
|
-5.13 |
-3.94 |
|
NIPTPPQNR |
10.80
|
-5.67 |
-4.48 |
|
NNIPTPPQN |
11.31
|
-4.86 |
-3.67 |
| P35197 |
SRPDHLPPS |
10.55
|
-6.20 |
-5.01 |
|
STPAKPPQE |
11.69
|
-6.96 |
-5.77 |
|
GFGSTPAKP |
12.12
|
-5.30 |
-4.11 |
| Q12446 |
PLPQLPNRN |
6.24
|
-9.63 |
-8.44 |
|
PAPPPPPRR |
6.77
|
-6.00 |
-4.81 |
|
PVPPPPPMR |
8.80
|
-6.90 |
-5.71 |
| P08018 |
TRPNVAPHK |
9.48
|
-7.93 |
-6.74 |
|
GPPPRLPSD |
11.26
|
-5.18 |
-3.99 |
|
QHPTRPNVA |
12.21
|
-5.22 |
-4.03 |
| P53552 |
LRPTGPDRG |
8.34
|
-7.43 |
-6.24 |
|
SRALRPTGP |
10.82
|
-4.90 |
-3.71 |
|
PTRPSKSKT |
13.33
|
-2.10 |
-0.91 |
| P39969 |
RRAPKPPSY |
8.75
|
-6.02 |
-4.83 |
|
SPIPSPTRN |
9.07
|
-5.53 |
-4.34 |
|
LLPPQPGSK |
10.73
|
-6.22 |
-5.03 |
| P46674 |
TRPNHFPFS |
10.31
|
-4.60 |
-3.41 |
|
INPVTPVLD |
12.52
|
-5.78 |
-4.59 |
|
STSPPLPSH |
14.31
|
-2.40 |
-1.21 |
| P14906 |
LKYGHPDGP |
13.94
|
-4.28 |
-3.09 |
| Q03790 |
GFPSAPQPL |
12.52
|
-5.66 |
-4.47 |
|
TATPSPFRP |
12.62
|
-5.00 |
-3.81 |
|
GLNGFPSAP |
12.78
|
-3.91 |
-2.72 |
| P40568 |
PMNAPTPAM |
12.45
|
-1.90 |
-0.71 |
|
PYPGSPMHS |
12.74
|
-4.59 |
-3.40 |
|
AMIPYPGSP |
12.79
|
-5.23 |
-4.04 |
| Q12443 |
PDPITVPAP |
13.48
|
-3.82 |
-2.63 |
|
EIPDPITVP |
13.84
|
-4.42 |
-3.23 |
|
IPDPITVPA |
14.77
|
-2.42 |
-1.23 |
| P41809 |
SSPSVPVAV |
13.13
|
-3.46 |
-2.27 |
|
SSPSAPVAI |
13.57
|
-2.41 |
-1.22 |
|
ALSTYPTTP |
13.59
|
-3.45 |
-2.26 |
| Q05080 |
RQKPDKPRP |
9.04
|
-4.05 |
-2.86 |
|
LRQKPDKPR |
10.70
|
-4.74 |
-3.55 |
|
QKPDKPRPI |
10.85
|
-6.70 |
-5.51 |
| P25344 |
ANTPGPSPN |
14.67
|
-3.06 |
-1.87 |
| P07248 |
NSPISPHKL |
11.18
|
-4.78 |
-3.59 |
|
SNSPISPHK |
12.46
|
-3.93 |
-2.74 |
|
NLSNSPISP |
14.01
|
-3.67 |
-2.48 |
| P53297 |
SLPPKPISK |
9.44
|
-7.06 |
-5.87 |
|
SNSSLPPKP |
10.40
|
-5.74 |
-4.55 |
|
SMPQMMPVM |
10.47
|
-7.08 |
-5.89 |
| P22147 |
SFPPPPPMT |
9.94
|
-7.06 |
-5.87 |
|
GMSIPPPAP |
11.28
|
-3.13 |
-1.94 |
|
LHPLHPHQM |
11.34
|
-5.97 |
-4.78 |
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