ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SHO1_2VKN-15.PDB
Scoring matrix: SHO1_2VKN-15_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 20.63
Foldx random average score for Saccharomyces cerevisiae: 16.305

Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
 Proteins belonging to other specie: 0
Nš of interactions described: 68
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1266459
Proteins after disorder filtering: 4065
 Total fragments: 43818
Proteins after pattern filtering: 1668
 Total fragments: 5281
Proteins after MINT filtering: 32
 Total fragments: 161

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

20.63

-1.02

0.00

Best peptides

RRRRIRRMK

0.00

-10.14

-9.12

         
Interactors      
P11710

LPLTPNSKY

15.46

-6.89

-5.87

PLPLTPNSK

15.74

-5.96

-4.94

Q06604

PLLPTRPNK

11.11

-9.48

-8.46

PPLPTRRDH

12.20

-8.08

-7.05

NIPSSKPAG

12.51

-4.09

-3.06

P24814

HPPDIHPNL

14.83

-5.50

-4.47

P24583

PPQPRKHDK

11.22

-7.96

-6.94

LPPQPRKHD

12.60

-8.24

-7.21

APLPPQPRK

14.97

-6.60

-5.57

Q06412

SPKSPRDSS

14.13

-6.04

-5.02

RPPPPPPLL

14.19

-8.54

-7.51

SPNSPKSPR

14.30

-6.37

-5.35

P40036

PPLSPKSTV

12.12

-5.12

-4.10

IELPPLSPK

15.82

-5.83

-4.80

LPPLSPKST

15.95

-5.29

-4.27

P18494

RSVVPILPK

12.68

-5.43

-4.40

VPILPKPSP

14.61

-5.84

-4.81

NTPVDSPSV

15.54

-3.26

-2.23

P40055

IPDVKPDVK

13.45

-6.83

-5.80

DIPDVKPDV

13.82

-2.56

-1.54

P09620

SNPISKPSI

12.00

-5.37

-4.35

NPISKPSIH

14.88

-4.37

-3.35

P13186

LPEREPPTY

13.24

-6.90

-5.88

RPPIPAALP

13.89

-6.99

-5.96

APSYVPNRV

15.62

-4.36

-3.34

P04051

LPHFPKNSK

9.01

-7.47

-6.45

DRSLPHFPK

13.64

-5.73

-4.71

RSLPHFPKN

15.46

-4.34

-3.31

P39083

PATPSNVSM

16.20

-4.84

-3.81

P38753

NLPIQHPTN

12.59

-6.24

-5.21

NTPVMPPQR

16.05

-5.90

-4.88

Q06524

NPTVPNELL

13.97

-8.02

-6.99

P40020

RPPPLTPEK

11.10

-7.47

-6.45

PLTPEKNLY

13.86

-5.04

-4.02

MSLPVTPVK

14.13

-4.52

-3.49

Q00246

NLPRLPTPF

14.14

-5.27

-4.24

EKNLPRLPT

15.94

-7.30

-6.28

LPRLPTPFA

15.94

-5.84

-4.81

P32448

PQLPSKDKS

13.74

-3.53

-2.50

SPQLPSKDK

15.08

-5.85

-4.82

RVPTDSPQL

15.30

-4.75

-3.73

Q08229

NPTIPPRSK

11.59

-7.04

-6.02

RPLPSTPNE

14.99

-4.57

-3.55

LPSTPNEDS

16.24

-5.97

-4.95

Q04439

PSSKPKEPM

12.66

-5.23

-4.21

PPPSSKPKE

13.94

-4.85

-3.82

RPSPPTAAT

14.57

-4.61

-3.59

P35197

RPDHLPPSQ

13.08

-4.88

-3.86

NQSRPDHLP

15.64

-7.01

-5.98

Q12446

PQLPNRNNR

12.30

-9.97

-8.95

PPPPPRASR

12.42

-10.80

-9.78

PPPPHRHVT

12.60

-9.37

-8.34

P08018

PPPRLPSDK

11.40

-10.34

-9.31

RAPRRPLST

11.89

-8.07

-7.04

TQHPTRPNV

12.74

-6.65

-5.63

P53552

LPTRPSKSK

10.11

-10.20

-9.17

PTRPSKSKT

14.79

-4.14

-3.11

RALRPTGPD

14.97

-7.64

-6.62

P39969

RRAPKPPSY

13.61

-4.87

-3.85

PRRAPKPPS

14.68

-4.97

-3.94

LPPQPGSKK

14.83

-5.93

-4.90

P46674

VATRPNHFP

16.14

-5.78

-4.76

Q03790

FPSAPQPLF

15.83

-5.94

-4.92

P40568

PGSPMHSIM

13.69

-7.08

-6.05

YPGSPMHSI

15.42

-5.86

-4.84

MIPYPGSPM

15.59

-5.41

-4.38

Q12443

PITVPAPTR

16.13

-6.62

-5.60

P22147

HPLHPHQMP

12.86

-6.97

-5.95

IPTPPHPMN

14.17

-6.59

-5.56

LHPLHPHQM

15.21

-5.65

-4.63

Q05080

KPDKPRPIV

8.70

-9.02

-7.99

RQKPDKPRP

10.80

-5.99

-4.96

P07248

SPISPHKLI

12.92

-8.13

-7.11

NSPISPHKL

15.76

-4.01

-2.98

SNSPISPHK

16.27

-2.38

-1.36

P53297

YHPSMPQMM

12.81

-5.45

-4.43

MPQMMPVMG

14.00

-8.00

-6.97

LPPKPISKT

14.29

-5.69

-4.67

 


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