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Matrix information:
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ADAN-name: SHO1_2VKN-13.PDB
Scoring matrix: SHO1_2VKN-13_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 18.16
Foldx random average score for Saccharomyces cerevisiae: 13.077 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3214721
Proteins after random average filtering: 7179
Total fragments: 1487225
Proteins after disorder filtering: 4392
Total fragments: 57341
Proteins after pattern filtering: 2047
Total fragments: 9811
Proteins after MINT filtering: 35
Total fragments: 290 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAAAA |
18.16
|
-2.17 |
0.00 |
| Best peptides |
RPPRFDRF |
0.00
|
-12.58 |
-10.41 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPN |
11.69
|
-6.65 |
-4.48 |
|
LPLTPNSK |
12.35
|
-6.06 |
-3.89 |
|
SKPLPLTP |
12.41
|
-6.68 |
-4.51 |
| Q06604 |
KPLLPTRP |
5.99
|
-10.19 |
-8.02 |
|
PPPLPTRR |
6.62
|
-10.22 |
-8.05 |
|
GPRMPSRG |
7.97
|
-9.45 |
-7.28 |
| P24814 |
NSTRPQMP |
10.40
|
-8.28 |
-6.11 |
|
PPDIHPNL |
11.11
|
-6.76 |
-4.59 |
|
HPNLGPQL |
11.13
|
-6.07 |
-3.90 |
| P24583 |
LPPQPRKH |
8.94
|
-8.73 |
-6.56 |
|
PLPPQPRK |
10.08
|
-8.22 |
-6.05 |
|
NAPLPPQP |
11.57
|
-8.41 |
-6.24 |
| Q06412 |
NSPKSPRD |
7.31
|
-6.08 |
-3.91 |
|
RPPPPPPL |
8.78
|
-9.39 |
-7.22 |
|
PPPPPPLL |
9.34
|
-8.40 |
-6.23 |
| P40036 |
LPPLSPKS |
9.28
|
-8.62 |
-6.45 |
|
LPTTPGIR |
10.23
|
-8.12 |
-5.95 |
|
ELPPLSPK |
12.95
|
-5.86 |
-3.69 |
| P18494 |
RSVVPILP |
8.55
|
-7.74 |
-5.57 |
|
VVPILPKP |
10.62
|
-8.63 |
-6.46 |
|
LPKPSPNS |
11.82
|
-4.15 |
-1.98 |
| P40055 |
PDVKPDVK |
11.07
|
-7.11 |
-4.94 |
| P09620 |
PSNIPQMH |
11.80
|
-6.53 |
-4.36 |
|
NPISKPSI |
11.96
|
-4.85 |
-2.68 |
|
PISKPSIH |
12.05
|
-6.99 |
-4.82 |
| P13186 |
RPPIPAAL |
7.93
|
-9.14 |
-6.97 |
|
LPEREPPT |
9.58
|
-9.38 |
-7.21 |
|
PSYVPNRV |
10.29
|
-7.07 |
-4.90 |
| P04051 |
SLPHFPKN |
8.65
|
-8.31 |
-6.14 |
|
DRSLPHFP |
10.91
|
-10.61 |
-8.44 |
|
LPHFPKNS |
11.30
|
-6.55 |
-4.38 |
| P39083 |
SPATPSNV |
12.52
|
-5.59 |
-3.42 |
| P38753 |
YPSNLPIQ |
9.41
|
-9.33 |
-7.16 |
|
TPVMPPQR |
10.34
|
-7.69 |
-5.52 |
|
PVMPPQRQ |
10.61
|
-7.37 |
-5.20 |
| Q06524 |
WKYNPTVP |
11.06
|
-6.88 |
-4.71 |
|
NPTVPNEL |
12.41
|
-4.29 |
-2.12 |
| P40020 |
RPPPLTPE |
8.51
|
-9.32 |
-7.15 |
|
EPTSPTRQ |
8.77
|
-8.02 |
-5.85 |
|
PPLPFPLY |
8.88
|
-9.19 |
-7.02 |
| Q00246 |
NLPRLPTP |
9.92
|
-8.68 |
-6.51 |
|
LPRLPTPF |
10.42
|
-7.36 |
-5.19 |
|
EKNLPRLP |
10.55
|
-9.78 |
-7.61 |
| P32448 |
SPQLPSKD |
10.34
|
-7.81 |
-5.64 |
|
RVPTDSPQ |
12.39
|
-6.36 |
-4.19 |
|
VPTDSPQL |
12.86
|
-2.88 |
-0.71 |
| Q08229 |
NPTIPPRS |
6.45
|
-8.51 |
-6.34 |
|
YNPTIPPR |
11.18
|
-6.23 |
-4.06 |
|
RPLPSTPN |
11.19
|
-5.01 |
-2.84 |
| Q04439 |
KPKEPMFE |
7.21
|
-8.64 |
-6.47 |
|
SKPKEPMF |
8.53
|
-6.33 |
-4.16 |
|
APPPPGMQ |
10.62
|
-8.64 |
-6.47 |
| P35197 |
RPDHLPPS |
8.22
|
-9.88 |
-7.71 |
|
TPAKPPQE |
9.39
|
-8.49 |
-6.32 |
|
PDHLPPSQ |
12.73
|
-6.70 |
-4.53 |
| Q12446 |
APPPPPRR |
7.26
|
-9.50 |
-7.33 |
|
PPPPPHRH |
7.89
|
-8.94 |
-6.77 |
|
APPPPPRA |
8.15
|
-8.99 |
-6.82 |
| P08018 |
RAPRRPLS |
7.58
|
-9.52 |
-7.35 |
|
RPNVAPHK |
8.76
|
-9.44 |
-7.27 |
|
HPTRPNVA |
8.83
|
-7.70 |
-5.53 |
| P53552 |
RPTGPDRG |
6.27
|
-10.51 |
-8.34 |
|
LPTRPSKS |
8.63
|
-8.72 |
-6.55 |
|
RALRPTGP |
10.57
|
-7.47 |
-5.30 |
| P39969 |
QPPKSPLL |
7.70
|
-7.45 |
-5.28 |
|
SPRRAPKP |
9.94
|
-11.69 |
-9.52 |
|
RRAPKPPS |
9.95
|
-8.30 |
-6.13 |
| P46674 |
RPNHFPFS |
4.84
|
-11.00 |
-8.83 |
|
NPVTPVLD |
9.20
|
-8.01 |
-5.84 |
|
SSTSPPLP |
12.56
|
-5.61 |
-3.44 |
| P14906 |
KYGHPDGP |
12.05
|
-6.50 |
-4.33 |
| Q03790 |
ATPSPFRP |
10.43
|
-5.52 |
-3.35 |
|
FPSAPQPL |
12.76
|
-7.55 |
-5.38 |
| P40568 |
TPAMIPYP |
8.84
|
-8.29 |
-6.12 |
|
YPGSPMHS |
11.31
|
-8.05 |
-5.88 |
|
PYPGSPMH |
12.60
|
-5.17 |
-3.00 |
| Q12443 |
IPDPITVP |
11.89
|
-6.53 |
-4.36 |
| P41809 |
YPTTPYPS |
12.26
|
-6.78 |
-4.61 |
|
TPYPSPNS |
12.39
|
-3.75 |
-1.58 |
| Q05080 |
QKPDKPRP |
8.99
|
-5.76 |
-3.59 |
|
LRQKPDKP |
9.47
|
-8.48 |
-6.31 |
|
KPDKPRPI |
9.54
|
-7.95 |
-5.78 |
| P25344 |
TPGPSPNE |
11.80
|
-4.08 |
-1.91 |
| P07248 |
NSPISPHK |
10.61
|
-6.32 |
-4.15 |
|
SPISPHKL |
10.90
|
-6.71 |
-4.54 |
| P53297 |
MFYHPSMP |
8.73
|
-8.58 |
-6.41 |
|
YPGGIPFQ |
8.86
|
-9.29 |
-7.12 |
|
MPQMMPVM |
9.87
|
-8.57 |
-6.40 |
| P22147 |
HPHQMPYP |
7.94
|
-7.78 |
-5.61 |
|
HPLHPHQM |
9.48
|
-6.36 |
-4.19 |
|
FPPPPPMT |
9.50
|
-10.03 |
-7.86 |
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