ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SHO1_1QKX-8.PDB
Scoring matrix: SHO1_1QKX-8_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.13
Foldx random average score for Saccharomyces cerevisiae: 12.131

Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
 Proteins belonging to other specie: 0
Nš of interactions described: 68
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1270616
Proteins after disorder filtering: 4476
 Total fragments: 70213
Proteins after pattern filtering: 2049
 Total fragments: 9476
Proteins after MINT filtering: 33
 Total fragments: 277

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.13

0.89

0.00

Best peptides

KWFWKFER

0.00

0.74

-0.15

         
Interactors      
P11710

PLTPNSKY

10.91

-3.75

-4.64

LPLTPNSK

11.64

-3.77

-4.66

Q06604

PRMPSRGR

5.99

-5.11

-6.00

KGPRMPSR

7.65

-6.47

-7.36

KNKPKPTP

7.85

-4.67

-5.56

P24814

DIHPNLGP

9.65

-4.44

-5.33

PPDIHPNL

10.76

-3.76

-4.65

PNLGPQLW

11.08

-3.36

-4.25

P40073

YPQQQPSH

9.42

-5.65

-6.54

P24583

APLPPQPR

8.60

-5.95

-6.84

ANAPLPPQ

10.73

-4.40

-5.29

PLPPQPRK

11.03

-2.85

-3.74

Q06412

PNSPKSPR

5.36

-4.55

-5.44

ERRPPPPP

9.20

-4.58

-5.47

PKSPRDSS

9.85

-5.42

-6.31

P40036

LPTTPGIR

11.21

-2.32

-3.21

PLSPKSTV

11.32

-1.99

-2.88

P18494

PILPKPSP

8.54

-5.16

-6.05

SVVPILPK

9.71

-5.57

-6.46

LPKPSPNS

11.41

-3.05

-3.94

P40055

IPDVKPDV

7.35

-5.04

-5.93

P09620

NPISKPSI

8.79

-5.08

-5.97

VPDPSNIP

10.79

-2.84

-3.73

PISKPSIH

11.19

-1.65

-2.54

P13186

APSYVPNR

8.80

-5.22

-6.11

SIPMSPNY

9.47

-1.86

-2.75

PEREPPTY

9.89

-3.41

-4.30

P04051

PHFPKNSK

6.75

-4.03

-4.92

RSLPHFPK

10.93

-3.08

-3.97

VNPAMLPG

11.20

-1.36

-2.25

P38753

TPVMPPQR

9.21

-6.31

-7.20

PYPSNLPI

9.23

-2.26

-3.15

SPYPSNLP

10.72

-3.25

-4.14

Q06524

NPTVPNEL

11.16

-3.05

-3.94

P40020

PPLPFPLY

8.41

-4.82

-5.71

TPESPLNR

8.46

-6.88

-7.77

RVLPPLPF

8.84

-6.09

-6.98

Q00246

KNLPRLPT

8.67

-6.40

-7.29

LPRLPTPF

9.66

-3.63

-4.52

EKNLPRLP

11.55

-3.07

-3.96

P32448

PQLPSKDK

11.01

-4.83

-5.72

VPTDSPQL

11.59

-3.39

-4.28

Q08229

YNPTIPPR

7.66

-2.75

-3.64

Q04439

SSKPKEPM

7.12

-4.26

-5.15

PKEPMFEA

9.00

-4.76

-5.65

SKKPAPPP

9.36

-4.27

-5.16

P35197

PAKPPQER

7.88

-4.66

-5.55

STPAKPPQ

9.37

-2.19

-3.08

SRPDHLPP

10.99

-3.97

-4.86

Q12446

PPPPRASR

7.50

-4.68

-5.57

APPPPPRR

8.05

-4.37

-5.26

VPPPPPMR

8.26

-3.78

-4.67

P08018

GPPPRLPS

9.49

-3.92

-4.81

PRLPSDKF

9.63

-3.42

-4.31

PPRLPSDK

10.74

-3.18

-4.07

P53552

LRPTGPDR

8.02

-2.95

-3.84

PTRPSKSK

11.03

-4.30

-5.19

PQGPKGGN

12.13

-2.08

-2.97

P39969

RRAPKPPS

7.44

-5.76

-6.65

SPIPSPTR

8.52

-5.92

-6.81

AQPPKSPL

9.23

-1.48

-2.37

P46674

TRPNHFPF

8.85

-3.52

-4.41

RPNHFPFS

10.69

-2.81

-3.70

ATRPNHFP

11.77

-3.10

-3.99

P14906

KYGHPDGP

11.89

-1.98

-2.87

Q03790

PSAPQPLF

10.88

-3.63

-4.52

NGFPSAPQ

10.92

-3.78

-4.67

PTATPSPF

11.84

-1.75

-2.64

P40568

YYHPMNAP

9.08

-4.01

-4.90

PYPGSPMH

9.09

-2.00

-2.89

IPYPGSPM

10.86

-3.83

-4.72

P41809

PYPSPNSY

9.43

-1.68

-2.57

STYPTTPY

11.06

-4.60

-5.49

TPYPSPNS

11.54

-2.75

-3.64

Q05080

QKPDKPRP

8.40

-3.24

-4.13

RQKPDKPR

8.83

-5.31

-6.20

KPDKPRPI

9.84

-4.66

-5.55

P07248

SNSPISPH

10.26

-3.60

-4.49

PISPHKLI

11.49

-2.95

-3.84

P53297

APEGKPPQ

7.86

-5.08

-5.97

MYMPFQPQ

8.07

-3.97

-4.86

FYHPSMPQ

8.60

-3.73

-4.62

P22147

PYNIPPGF

8.52

-5.66

-6.55

GLHPLHPH

9.66

-4.37

-5.26

LHPHQMPY

9.98

-1.64

-2.53

 


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