ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SHO1_1QKX-22.PDB
Scoring matrix: SHO1_1QKX-22_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 16.45
Foldx random average score for Saccharomyces cerevisiae: 14.763

Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
 Proteins belonging to other specie: 0
Nš of interactions described: 68
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1453979
Proteins after disorder filtering: 4846
 Total fragments: 84001
Proteins after pattern filtering: 1808
 Total fragments: 5235
Proteins after MINT filtering: 29
 Total fragments: 121

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

16.45

0.37

0.00

Best peptides

MRDRPKP

0.00

4.45

4.08

         
Interactors      
P11710

PLPLTPN

14.40

-2.37

-2.74

Q06604

PRMPSRG

13.23

-2.91

-3.28

RVKPAPP

13.24

-0.90

-1.27

KPLLPTR

13.56

-2.85

-3.22

P24814

PNLGPQL

10.97

-4.25

-4.62

TRPQMPS

12.90

-3.45

-3.82

HPNLGPQ

13.44

1.61

1.24

P24583

ANAPLPP

13.59

-0.71

-1.08

Q06412

ERRPPPP

10.78

-2.91

-3.28

PMVSPSS

12.92

-1.78

-2.15

RRPPPPP

14.16

-3.39

-3.76

P40036

PPLSPKS

11.82

-1.71

-2.08

P18494

VPILPKP

9.41

-2.78

-3.15

TPVDSPS

11.66

-0.44

-0.81

PVDSPSV

13.24

-0.94

-1.31

P40055

IPDVKPD

14.18

-1.18

-1.55

P09620

PISKPSI

13.62

-0.58

-0.95

NPISKPS

14.65

-0.52

-0.89

P13186

IPAALPP

11.59

-3.45

-3.82

LPEREPP

11.82

-3.11

-3.48

PAALPPS

12.90

-1.75

-2.12

P04051

LPHFPKN

13.40

-0.53

-0.90

PAMLPGS

14.16

-2.37

-2.74

NPAMLPG

14.48

-0.78

-1.15

P38753

TPVMPPQ

11.01

-2.54

-2.91

PIQHPTN

12.62

-0.44

-0.81

NNTPVMP

13.79

-0.16

-0.53

Q08229

TPVQPGG

14.18

-2.21

-2.58

P40020

PPYLSPQ

11.04

-2.40

-2.77

PYLSPQN

11.46

-4.11

-4.48

NPHSIPF

13.74

0.22

-0.15

Q00246

PRLPTPF

11.41

-2.36

-2.73

NLPRLPT

14.48

-1.15

-1.52

P32448

PTDSPQL

12.98

-2.09

-2.46

VPTDSPQ

13.24

-0.67

-1.04

PRVPTDS

14.45

-2.13

-2.50

Q04439

KPKEPMF

11.95

-1.26

-1.63

ANIPPPP

11.96

-1.49

-1.86

PSSKPKE

12.38

-1.87

-2.24

P35197

RPDHLPP

6.96

-0.83

-1.20

TPAKPPQ

12.26

-2.20

-2.57

Q12446

PRRGPAP

9.23

-2.76

-3.13

PPRRGPA

10.72

-2.25

-2.62

VPVAPPP

11.15

-3.31

-3.68

P08018

PNVAPHK

10.62

-2.71

-3.08

APRRPLS

13.27

-1.64

-2.01

TRPNVAP

13.87

-3.64

-4.01

P53552

RPTGPDR

14.07

-2.17

-2.54

LPQGPKG

14.66

-0.63

-1.00

P39969

PRRAPKP

5.67

-2.45

-2.82

RRAPKPP

10.96

-0.92

-1.29

SPRRAPK

12.12

-2.15

-2.52

P46674

RPNHFPF

10.43

-1.61

-1.98

PNHFPFS

10.50

-1.55

-1.92

TRPNHFP

13.34

-3.19

-3.56

P14906

HPDGPQS

13.16

1.15

0.78

GHPDGPQ

13.93

-2.25

-2.62

Q03790

KPTATPS

14.44

-2.11

-2.48

P40568

PMNAPTP

12.66

-1.32

-1.69

HPMNAPT

13.19

0.46

0.09

TPAMIPY

13.25

-0.37

-0.74

P22147

PHQMPYP

9.95

-3.37

-3.74

IPKGEPF

10.66

-3.24

-3.61

PISFPPP

10.93

-1.83

-2.20

Q05080

KPDKPRP

10.91

-3.08

-3.45

RQKPDKP

12.11

0.18

-0.19

P53297

MPFQPQP

10.81

-2.44

-2.81

MPQMMPV

11.64

-1.54

-1.91

PQMMPVM

12.26

-3.64

-4.01

 


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