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Matrix information:
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ADAN-name: SHO1_1QKX-17.PDB
Scoring matrix: SHO1_1QKX-17_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 17.05
Foldx random average score for Saccharomyces cerevisiae: 21.403 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1668308
Proteins after disorder filtering: 4714
Total fragments: 117337
Proteins after pattern filtering: 2188
Total fragments: 11117
Proteins after MINT filtering: 37
Total fragments: 353 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
AAAAAGAAA |
17.05
|
3.52 |
0.00 |
| Best peptides |
FEFKWGRGR |
0.00
|
3.76 |
0.24 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPNS |
14.97
|
-0.44 |
-3.96 |
|
PLTPNSKYN |
18.39
|
2.44 |
-1.08 |
|
SKPLPLTPN |
19.90
|
0.99 |
-2.53 |
| Q06604 |
GPRMPSRGR |
7.48
|
-3.37 |
-6.89 |
|
KPLLPTRPN |
13.26
|
-3.02 |
-6.54 |
|
LPTRPNKAE |
14.79
|
-1.73 |
-5.25 |
| P24814 |
PDIHPNLGP |
16.66
|
1.28 |
-2.24 |
|
NSTRPQMPS |
16.91
|
0.69 |
-2.83 |
|
IHPNLGPQL |
19.70
|
1.95 |
-1.57 |
| P40073 |
FDGYPQQQP |
19.04
|
0.43 |
-3.09 |
|
GYPQQQPSH |
21.34
|
4.81 |
1.29 |
| P24583 |
LPPQPRKHD |
15.83
|
-2.74 |
-6.26 |
|
APLPPQPRK |
18.34
|
0.04 |
-3.48 |
| Q06412 |
PPPPLSTSR |
15.24
|
-2.02 |
-5.54 |
|
SPNSPKSPR |
18.21
|
0.77 |
-2.75 |
|
GFSPNSPKS |
18.51
|
1.97 |
-1.55 |
| P40036 |
LPTTPGIRS |
15.06
|
-0.64 |
-4.16 |
|
ELPPLSPKS |
18.29
|
1.25 |
-2.27 |
|
PTTPGIRSG |
18.79
|
-2.07 |
-5.59 |
| P18494 |
ILPKPSPNS |
14.74
|
1.08 |
-2.44 |
|
PVDSPSVSR |
17.98
|
0.74 |
-2.78 |
|
FNTPVDSPS |
18.83
|
1.52 |
-2.00 |
| P40055 |
PDVKPDVKG |
14.41
|
0.31 |
-3.21 |
|
SDIPDVKPD |
19.06
|
4.46 |
0.94 |
| P09620 |
LSNPISKPS |
16.35
|
1.01 |
-2.51 |
|
PDPSNIPQM |
18.53
|
1.27 |
-2.25 |
|
PSNIPQMHA |
18.63
|
1.14 |
-2.38 |
| P13186 |
IPMSPNYGN |
15.49
|
1.16 |
-2.36 |
|
KAPSYVPNR |
16.96
|
-0.45 |
-3.97 |
|
NNIPLTPLA |
17.38
|
2.57 |
-0.95 |
| P04051 |
VNPAMLPGS |
16.28
|
2.56 |
-0.96 |
|
PAMLPGSSN |
17.10
|
-0.02 |
-3.54 |
|
LPHFPKNSK |
18.69
|
-0.32 |
-3.84 |
| P32334 |
FSSPSSPTT |
21.26
|
3.49 |
-0.03 |
| P39083 |
LQSPATPSN |
15.06
|
2.89 |
-0.63 |
|
PATPSNVSM |
18.29
|
-1.79 |
-5.31 |
|
LLQSPATPS |
20.92
|
2.21 |
-1.31 |
| P38753 |
SPPVPGPAL |
15.55
|
-1.53 |
-5.05 |
|
PVMPPQRQS |
16.07
|
-1.96 |
-5.48 |
|
PIQHPTNSA |
17.62
|
-0.43 |
-3.95 |
| Q06524 |
WKYNPTVPN |
16.98
|
2.14 |
-1.38 |
|
KYNPTVPNE |
19.09
|
1.85 |
-1.67 |
|
NPTVPNELL |
20.52
|
0.95 |
-2.57 |
| P40020 |
LPPYLSPQN |
15.78
|
-0.06 |
-3.58 |
|
VNPHSIPFS |
17.73
|
3.36 |
-0.16 |
|
YLTPESPLN |
17.82
|
0.89 |
-2.63 |
| Q00246 |
LPRLPTPFA |
14.67
|
-2.07 |
-5.59 |
|
LPESPGTLD |
17.11
|
2.74 |
-0.78 |
|
SNLPESPGT |
17.18
|
3.75 |
0.23 |
| P32448 |
TDSPQLPSK |
18.51
|
2.47 |
-1.05 |
|
PQLPSKDKS |
18.94
|
1.81 |
-1.71 |
|
PRVPTDSPQ |
20.55
|
0.33 |
-3.19 |
| Q08229 |
LPTPVQPGG |
13.30
|
-2.96 |
-6.48 |
|
PSTPNEDSR |
17.65
|
1.44 |
-2.08 |
|
TRPLPSTPN |
19.00
|
1.66 |
-1.86 |
| Q04439 |
APPPPGMQN |
14.14
|
0.24 |
-3.28 |
|
PSSKPKEPM |
16.25
|
-1.15 |
-4.67 |
|
PKEPMFEAA |
18.63
|
1.26 |
-2.26 |
| P35197 |
GSTPAKPPQ |
18.57
|
1.38 |
-2.14 |
|
NQSRPDHLP |
19.55
|
-0.45 |
-3.97 |
|
PAKPPQERS |
20.39
|
0.81 |
-2.71 |
| Q12446 |
LPQLPNRNN |
13.18
|
-2.66 |
-6.18 |
|
PPPPASLGQ |
13.94
|
-0.79 |
-4.31 |
|
PPPPPRRGP |
13.98
|
-5.38 |
-8.90 |
| P08018 |
STQHPTRPN |
15.73
|
-0.49 |
-4.01 |
|
PRLPSDKFS |
17.70
|
0.35 |
-3.17 |
|
APRRPLSTQ |
18.37
|
-0.52 |
-4.04 |
| P53552 |
LPTRPSKSK |
13.75
|
-1.17 |
-4.69 |
|
QALPQGPKG |
15.03
|
-1.14 |
-4.66 |
|
LPQGPKGGN |
15.88
|
-0.88 |
-4.40 |
| P39969 |
KLLPPQPGS |
14.44
|
-0.83 |
-4.35 |
|
LPPQPGSKK |
15.53
|
-2.15 |
-5.67 |
|
PIPSPTRNS |
16.13
|
-0.47 |
-3.99 |
| P46674 |
PVTPVLDGA |
17.71
|
0.95 |
-2.57 |
|
TRPNHFPFS |
18.10
|
2.76 |
-0.76 |
|
PVSTPSHSN |
18.92
|
1.71 |
-1.81 |
| P14906 |
YGHPDGPQS |
15.26
|
2.31 |
-1.21 |
|
KYGHPDGPQ |
17.09
|
0.25 |
-3.27 |
|
PDGPQSTSH |
19.96
|
3.05 |
-0.47 |
| Q03790 |
PTATPSPFR |
17.41
|
0.48 |
-3.04 |
|
LNGFPSAPQ |
17.63
|
1.65 |
-1.87 |
|
FDGKPTATP |
18.09
|
2.03 |
-1.49 |
| P40568 |
MIPYPGSPM |
15.30
|
-0.60 |
-4.12 |
|
PMNAPTPAM |
17.34
|
-1.32 |
-4.84 |
|
PGSPMHSIM |
18.38
|
-0.57 |
-4.09 |
| Q12443 |
IPDPITVPA |
17.54
|
1.16 |
-2.36 |
|
PITVPAPTR |
19.29
|
-0.38 |
-3.90 |
| P41809 |
TSSPSAPAA |
17.40
|
1.49 |
-2.03 |
|
TTPYPSPNS |
18.89
|
3.89 |
0.37 |
|
PSAPAAISS |
19.28
|
1.96 |
-1.56 |
| Q05080 |
LRQKPDKPR |
12.08
|
-1.33 |
-4.85 |
|
KPDKPRPIV |
20.06
|
-0.01 |
-3.53 |
| P25344 |
TANTPGPSP |
18.74
|
1.33 |
-2.19 |
|
NTPGPSPNE |
20.71
|
4.52 |
1.00 |
| P07248 |
SNSPISPHK |
18.76
|
0.83 |
-2.69 |
| P53297 |
MFYHPSMPQ |
14.05
|
0.57 |
-2.95 |
|
GFPMGGPSA |
14.60
|
-0.14 |
-3.66 |
|
FYHPSMPQM |
14.67
|
-0.51 |
-4.03 |
| P22147 |
PPAPHGFGQ |
11.78
|
1.10 |
-2.42 |
|
IPTPPHPMN |
17.22
|
-1.36 |
-4.88 |
|
EIPKGEPFD |
17.84
|
3.02 |
-0.50 |
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