ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SHO1_1QCF-7.PDB
Scoring matrix: SHO1_1QCF-7_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 11.88
Foldx random average score for Saccharomyces cerevisiae: 15.960

Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
 Proteins belonging to other specie: 0
Nš of interactions described: 68
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1407349
Proteins after disorder filtering: 4791
 Total fragments: 102376
Proteins after pattern filtering: 2344
 Total fragments: 18496
Proteins after MINT filtering: 37
 Total fragments: 563

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

11.88

-3.25

0.00

Best peptides

MRRPPPKH

0.00

-2.04

1.21

         
Interactors      
P11710

KPLPLTPN

5.00

-7.42

-4.17

PLTPNSKY

9.52

-7.14

-3.89

Q06604

PPSPPAKR

4.88

-9.19

-5.94

KPAPPVSR

5.62

-7.46

-4.21

VKPAPPVS

5.85

-8.07

-4.82

P24814

STRPQMPS

8.34

-4.47

-1.22

PNLGPQLW

8.66

-6.94

-3.69

DIHPNLGP

12.71

-3.36

-0.11

P40073

DGYPQQQP

11.02

-4.88

-1.63

YPQQQPSH

13.66

-5.54

-2.29

P24583

APLPPQPR

6.17

-8.11

-4.86

ANAPLPPQ

6.70

-6.39

-3.14

PLPPQPRK

8.29

-9.34

-6.09

Q06412

RPPPPPPL

3.98

-9.34

-6.09

RRPPPPPP

4.66

-9.09

-5.84

TKPPPPLS

5.67

-8.61

-5.36

P40036

ELPPLSPK

4.97

-7.36

-4.11

IELPPLSP

8.78

-5.70

-2.45

PLSPKSTV

9.73

-5.99

-2.74

P18494

QNTPSAPA

8.54

-3.74

-0.49

TPSAPATA

8.61

-5.74

-2.49

LPKPSPNS

10.48

-3.57

-0.32

P40055

SDIPDVKP

7.81

-6.35

-3.10

PDVKPDVK

12.05

-10.04

-6.79

IPDVKPDV

15.34

-3.96

-0.71

P09620

VPDPSNIP

8.47

-5.90

-2.65

PISKPSIH

12.75

-7.60

-4.35

SNPISKPS

15.10

-3.54

-0.29

P13186

IPAALPPS

6.48

-4.66

-1.41

NNIPLTPL

7.46

-4.79

-1.54

PLTPLATN

7.54

-6.58

-3.33

P04051

RSLPHFPK

6.12

-6.48

-3.23

VNPAMLPG

7.90

-6.16

-2.91

PHFPKNSK

9.63

-5.44

-2.19

P32334

FSSPSSPT

8.49

-4.61

-1.36

PSSPTTTD

13.01

-3.05

0.20

P39083

PATPSNVS

9.54

-4.01

-0.76

QSPATPSN

11.77

-3.39

-0.14

LQSPATPS

12.38

-5.28

-2.03

P38753

HISPPVPG

7.79

-6.95

-3.70

PPVPGPAL

9.87

-5.14

-1.89

SPYPSNLP

10.16

-4.99

-1.74

Q06524

PTVPNELL

9.21

-5.71

-2.46

KYNPTVPN

9.72

-4.46

-1.21

WKYNPTVP

14.67

-6.96

-3.71

P40020

RVLPPLPF

4.80

-7.85

-4.60

RPPPLTPE

5.27

-6.18

-2.93

VLPPLPFP

6.62

-8.35

-5.10

Q00246

KNLPRLPT

8.68

-4.97

-1.72

SNLPESPG

9.39

-5.13

-1.88

PRLPTPFA

9.87

-4.23

-0.98

P32448

TDSPQLPS

6.80

-5.25

-2.00

PQLPSKDK

9.26

-4.01

-0.76

PRVPTDSP

12.61

-4.22

-0.97

Q08229

RPLPSTPN

5.69

-5.13

-1.88

PTIPPRSK

8.02

-6.83

-3.58

PSTPNEDS

10.82

-4.37

-1.12

Q04439

KPAPPPPG

5.17

-9.08

-5.83

IPTPPQNR

6.04

-5.52

-2.27

PPPPPPPS

6.13

-8.82

-5.57

P35197

PAKPPQER

7.18

-6.92

-3.67

STPAKPPQ

8.84

-4.86

-1.61

QSRPDHLP

9.51

-6.20

-2.95

Q12446

PAPPPPPH

4.89

-8.77

-5.52

PAPPPPPR

5.45

-8.83

-5.58

RPLPQLPN

5.59

-5.45

-2.20

P08018

PRLPSDKF

4.70

-5.60

-2.35

PRRPLSTQ

5.94

-6.50

-3.25

GPPPRLPS

9.74

-4.12

-0.87

P53552

QALPQGPK

7.13

-5.67

-2.42

PTRPSKSK

8.29

-4.63

-1.38

RPTGPDRG

10.48

-9.77

-6.52

P39969

RRAPKPPS

5.57

-7.70

-4.45

KLLPPQPG

5.90

-8.19

-4.94

PSPAQPPK

6.86

-5.72

-2.47

P46674

TSPPLPSH

5.52

-5.75

-2.50

STSPPLPS

8.11

-6.34

-3.09

PINPVTPV

10.44

-4.84

-1.59

P14906

YGHPDGPQ

7.19

-5.40

-2.15

PDGPQSTS

9.02

-5.34

-2.09

HPDGPQST

10.78

-4.70

-1.45

Q03790

PSAPQPLF

6.79

-6.16

-2.91

FPSAPQPL

7.37

-7.18

-3.93

NGFPSAPQ

8.30

-3.91

-0.66

P40568

PMNAPTPA

7.15

-8.04

-4.79

IPYPGSPM

8.58

-3.44

-0.19

PGSPMHSI

9.94

-5.33

-2.08

Q12443

IPDPITVP

13.18

-3.29

-0.04

PITVPAPT

14.78

-8.03

-4.78

P41809

TSSPSVPV

7.69

-3.70

-0.45

TSSPSAPV

7.89

-3.71

-0.46

TSSPSAPA

7.94

-3.30

-0.05

Q05080

RQKPDKPR

5.49

-7.59

-4.34

PDKPRPIV

7.50

-6.71

-3.46

KPDKPRPI

12.17

-8.54

-5.29

P25344

TPGPSPNE

8.40

-2.71

0.54

NTPGPSPN

8.78

-5.26

-2.01

ANTPGPSP

13.09

-3.80

-0.55

P07248

PISPHKLI

9.12

-6.98

-3.73

SNSPISPH

11.85

-4.55

-1.30

NSPISPHK

13.61

-4.11

-0.86

P53297

MYMPFQPQ

6.09

-6.52

-3.27

SSLPPKPI

7.53

-6.77

-3.52

FYHPSMPQ

7.58

-4.99

-1.74

P22147

SFPPPPPM

4.52

-7.51

-4.26

SIPPPAPH

5.33

-7.09

-3.84

IPTPPHPM

5.75

-5.62

-2.37

 


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