ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SHO1_1QCF-12.PDB
Scoring matrix: SHO1_1QCF-12_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 12.74
Foldx random average score for Saccharomyces cerevisiae: 15.325

Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
 Proteins belonging to other specie: 0
Nš of interactions described: 68
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1651430
Proteins after disorder filtering: 4787
 Total fragments: 128351
Proteins after pattern filtering: 2251
 Total fragments: 11955
Proteins after MINT filtering: 37
 Total fragments: 395

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

12.74

-1.06

0.00

Best peptides

RRIPRRRR

0.00

-4.53

-3.47

         
Interactors      
P11710

SKPLPLTP

5.62

-3.37

-2.31

Q06604

PRMPSRGR

5.35

-7.08

-6.02

PSPPAKRI

5.91

-5.66

-4.60

SSPPPLPT

6.28

-4.62

-3.56

P24814

HPPDIHPN

8.47

-5.49

-4.43

NSTRPQMP

8.90

-3.69

-2.63

PDIHPNLG

9.39

-3.32

-2.26

P40073

GYPQQQPS

8.12

-4.03

-2.97

DGYPQQQP

15.21

-4.19

-3.13

P24583

LPPQPRKH

6.73

-5.84

-4.78

RANAPLPP

8.82

-2.14

-1.08

PLPPQPRK

13.59

-6.85

-5.79

Q06412

KPPPPLST

7.67

-3.71

-2.65

PPPPPLLY

7.90

-4.15

-3.09

PPPPLLYS

8.08

-3.68

-2.62

P40036

LPTTPGIR

12.76

-2.03

-0.97

SKSLPTTP

12.76

-2.42

-1.36

PTTPGIRS

12.86

-4.02

-2.96

P18494

SVVPILPK

6.48

-4.62

-3.56

VPILPKPS

6.50

-6.81

-5.75

PKPSPNSA

8.44

-2.00

-0.94

P40055

DIPDVKPD

7.74

-4.89

-3.83

PDVKPDVK

11.71

-1.04

0.02

SDIPDVKP

14.41

-5.76

-4.70

P09620

SNPISKPS

7.47

-4.23

-3.17

PSNIPQMH

8.53

-3.31

-2.25

VPDPSNIP

13.18

-2.13

-1.07

P13186

SYVPNRVP

6.09

-6.58

-5.52

PIPAALPP

7.89

-3.52

-2.46

QNNIPLTP

8.51

-2.30

-1.24

P04051

DRSLPHFP

8.25

-5.31

-4.25

VNPAMLPG

8.47

-2.99

-1.93

PAMLPGSS

10.33

-2.55

-1.49

P32334

PSSPTTTD

14.57

-2.29

-1.23

P39083

PATPSNVS

11.63

-3.41

-2.35

LQSPATPS

14.20

-3.01

-1.95

P38753

PVMPPQRQ

5.90

-6.35

-5.29

PYPSNLPI

7.47

-2.41

-1.35

NLPIQHPT

7.51

-5.76

-4.70

Q06524

PTVPNELL

10.40

-2.88

-1.82

NPTVPNEL

12.87

-1.27

-0.21

P40020

DRPPPLTP

5.53

-4.41

-3.35

SLPPYLSP

7.33

-3.59

-2.53

PLPFPLYD

7.40

-3.45

-2.39

Q00246

EKNLPRLP

6.11

-4.53

-3.47

SSNLPESP

11.32

0.91

1.97

KNLPRLPT

14.15

-4.81

-3.75

P32448

TDSPQLPS

9.11

-2.04

-0.98

PRVPTDSP

10.17

-3.34

-2.28

PTDSPQLP

10.58

-2.56

-1.50

Q08229

PTIPPRSK

3.49

-8.20

-7.14

LPTPVQPG

10.14

-3.84

-2.78

TPVQPGGH

11.83

-2.63

-1.57

Q04439

GSPSELPL

7.36

-3.74

-2.68

PTPPQNRD

7.77

-5.46

-4.40

PPPSSKPK

8.38

-3.95

-2.89

P35197

SRPDHLPP

5.34

-4.72

-3.66

GSTPAKPP

8.71

-4.81

-3.75

FGSTPAKP

11.40

-1.83

-0.77

Q12446

PPPPPRRG

4.60

-8.55

-7.49

NRPLPQLP

6.39

-5.21

-4.15

PPPPPHRH

6.44

-6.41

-5.35

P08018

DGPPPRLP

5.63

-6.09

-5.03

GPPPRLPS

7.17

-4.27

-3.21

TRPNVAPH

9.32

-3.63

-2.57

P53552

PTGPDRGD

8.97

-3.75

-2.69

TQALPQGP

9.67

-3.26

-2.20

PQGPKGGN

12.80

-1.63

-0.57

P39969

PKPPSYPS

7.02

-4.39

-3.33

PKSPLLNN

8.09

-2.03

-0.97

VSPRRAPK

8.21

-4.40

-3.34

P46674

TRPNHFPF

6.74

-4.53

-3.47

STSPPLPS

8.24

-2.43

-1.37

PVTPVLDG

10.29

-2.45

-1.39

P14906

HPDGPQST

12.49

-1.27

-0.21

KYGHPDGP

15.08

0.98

2.04

Q03790

ATPSPFRP

5.76

-4.37

-3.31

FPSAPQPL

10.75

-2.80

-1.74

GKPTATPS

11.99

-3.19

-2.13

P40568

PAMIPYPG

8.67

-4.69

-3.63

PGSPMHSI

9.85

-3.58

-2.52

YHPMNAPT

9.87

-4.04

-2.98

Q12443

PITVPAPT

10.72

-3.18

-2.12

P41809

PYPSPNSY

9.22

-2.26

-1.20

PSVPVAVS

9.78

-4.45

-3.39

TSSPSAPV

10.41

-2.96

-1.90

Q05080

KPDKPRPI

8.99

-4.87

-3.81

QKPDKPRP

12.10

-5.87

-4.81

RQKPDKPR

12.70

-5.13

-4.07

P25344

PGPSPNEA

10.31

-1.74

-0.68

P07248

SPISPHKL

7.20

-6.55

-5.49

PISPHKLI

9.38

-3.68

-2.62

LSNSPISP

14.51

-1.64

-0.58

P53297

GNISPHVP

7.40

-6.14

-5.08

MYMPFQPQ

7.62

-5.77

-4.71

GAPEGKPP

8.13

-4.64

-3.58

P22147

GQPISFPP

7.09

-4.44

-3.38

DEIPKGEP

8.13

-4.66

-3.60

SIPPPAPH

8.20

-4.70

-3.64

 


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