ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1OV32-5.PDB
Scoring matrix: SDC25_1OV32-5_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 14.72
Foldx random average score for Saccharomyces cerevisiae: 19.577

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1738091
Proteins after disorder filtering: 4680
 Total fragments: 140317
Proteins after pattern filtering: 2316
 Total fragments: 23911
Proteins after MINT filtering: 2
 Total fragments: 67


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

14.72

3.62

0.00

Best peptides

MDDEDPEDPW

0.00

4.18

0.56

         
Interactors      
P40450

LPQLPPPPPP

3.68

-7.01

-10.63

HDLVTPPAPP

4.13

-2.89

-6.51

LPPPPPPPPP

4.72

-6.46

-10.08

Q08601

RPMAPPPNQQ

6.17

-3.25

-6.87

PPPGPPPMAY

7.06

12.07

8.45

MAYNRPVYPP

8.35

-3.50

-7.12

 


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