ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1OV32-20.PDB
Scoring matrix: SDC25_1OV32-20_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.34
Foldx random average score for Saccharomyces cerevisiae: 17.067

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1431712
Proteins after disorder filtering: 4668
 Total fragments: 90393
Proteins after pattern filtering: 2141
 Total fragments: 9892
Proteins after MINT filtering: 2
 Total fragments: 19


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.34

3.72

0.00

Best peptides

MPPMRGEGD

0.00

-1.73

-5.45

         
Interactors      
P40450

PPLPNGLLS

12.86

0.65

-3.07

PPPLPQSLL

14.02

-1.82

-5.54

PPPLPDLFK

14.04

-1.27

-4.99

Q08601

YAPPPGPPP

12.63

-3.94

-7.66

YNRPVYPPP

15.93

-2.10

-5.82

YQRPMAPPP

15.96

3.78

0.06

 


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