ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1OV32-1.PDB
Scoring matrix: SDC25_1OV32-1_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 21.34
Foldx random average score for Saccharomyces cerevisiae: 22.294

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1859734
Proteins after disorder filtering: 4688
 Total fragments: 146538
Proteins after pattern filtering: 2308
 Total fragments: 22500
Proteins after MINT filtering: 2
 Total fragments: 63


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

21.34

-0.68

0.00

Best peptides

RDDERRWDIF

0.00

2.05

2.73

         
Interactors      
P40450

LPQLPPPPPP

10.07

-7.12

-6.44

LPPPPPPPPP

10.25

-6.96

-6.28

PPPPPPPPPP

11.51

-6.93

-6.25

Q08601

RPMAPPPNQQ

8.72

-4.34

-3.66

MAYNRPVYPP

12.94

-5.83

-5.15

YAPPPGPPPM

13.86

-4.86

-4.18

 


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