ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1JO8-19.PDB
Scoring matrix: SDC25_1JO8-19_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 13.46
Foldx random average score for Saccharomyces cerevisiae: 14.009

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1706580
Proteins after disorder filtering: 4672
 Total fragments: 100746
Proteins after pattern filtering: 2262
 Total fragments: 12478
Proteins after MINT filtering: 2
 Total fragments: 14


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

13.46

-2.56

0.00

Best peptides

IPSEPGEEF

0.00

-2.88

-0.32

         
Interactors      
P40450

PPLPESLSM

8.70

-7.21

-4.65

PPLPNGLLS

8.90

-4.17

-1.61

PPPPPLPES

10.15

-5.18

-2.62

Q08601

YAPPPGPPP

11.04

-7.12

-4.56

PGPPPMAYN

12.75

-3.41

-0.85

 


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