ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1JO8-17.PDB
Scoring matrix: SDC25_1JO8-17_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 11.3
Foldx random average score for Saccharomyces cerevisiae: 14.812

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1709633
Proteins after disorder filtering: 4684
 Total fragments: 100313
Proteins after pattern filtering: 2225
 Total fragments: 11107
Proteins after MINT filtering: 2
 Total fragments: 18


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

11.30

2.15

0.00

Best peptides

FRIRPGWAI

0.00

3.13

0.98

         
Interactors      
P40450

PPLPNGLLS

9.77

-0.82

-2.97

PAPPPLPDL

10.73

-1.78

-3.93

PPPPPLPQS

10.98

-0.53

-2.68

Q08601

YAPPPGPPP

10.70

-3.60

-5.75

YQRPMAPPP

13.07

-0.16

-2.31

YNRPVYPPP

13.56

-2.97

-5.12

 


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