ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: SDC25_1JO8-15.PDB
Scoring matrix: SDC25_1JO8-15_mat
Uniprot code: P14771
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 14.87
Foldx random average score for Saccharomyces cerevisiae: 10.732

Available information for P14771 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1755716
Proteins after disorder filtering: 4499
 Total fragments: 65448
Proteins after pattern filtering: 2028
 Total fragments: 7536
Proteins after MINT filtering: 2
 Total fragments: 15


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

14.87

-1.50

0.00

Best peptides

REFIILLDL

0.00

0.07

1.57

         
Interactors      
P40450

PPPLPQSLL

6.78

-4.17

-2.67

PPPLPESLS

7.68

-4.92

-3.42

APPLPNGLL

7.86

-3.48

-1.98

Q08601

RPMAPPPNQ

9.64

-4.63

-3.13

PPPGPPPMA

9.96

-3.57

-2.07

 


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