ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-8.PDB
Scoring matrix: RVS167_FYN-SSH-8_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 17.58
Foldx random average score for Saccharomyces cerevisiae: 16.472

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1954757
Proteins after disorder filtering: 4803
 Total fragments: 132738
Proteins after pattern filtering: 2321
 Total fragments: 19487
Proteins after MINT filtering: 74
 Total fragments: 1172


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

17.58

-1.94

0.00
Best peptides

RWRRLRRF

0.00

-2.72

-0.79
         
Interactors      
P38140

QPDLPPRK

9.38

-6.97

-5.04

IQPDLPPR

11.39

-5.90

-3.97

PDLPPRKI

12.08

-7.53

-5.60
Q06604

PSPPAKRI

8.79

-4.70

-2.77

PPLPTRRD

10.12

-7.22

-5.29

EKPLLPTR

10.72

-6.59

-4.65
Q12365

PREPLRNE

10.07

-6.96

-5.03

QIPFIPPQ

11.30

-2.76

-0.82

VPREPLRN

11.64

-6.66

-4.72
P40072

TPSASPML

12.77

-5.01

-3.07

APPTTKPG

13.29

-4.41

-2.48

AAPPTTKP

14.65

-4.84

-2.90
P40956

PPLPRRRA

8.23

-5.62

-3.69

TPPLPRRR

9.29

-6.37

-4.44

STPPLPRR

9.62

-5.13

-3.19
Q06833

RRPVPRRP

7.25

-4.54

-2.61

RPVPRRPS

10.98

-7.11

-5.18

PRRPSQPL

11.02

-4.84

-2.90
P40032

FPSILPNV

11.19

-6.08

-4.14

VPHSDPSA

12.92

-3.21

-1.27

SILPNVPH

13.17

-3.17

-1.23
P32628

EPPIAPES

13.25

-3.56

-1.63

PPIAPESA

15.78

-1.44

0.50
Q12242

TKPCDVPN

11.91

-2.47

-0.54

KPCDVPNN

13.46

-6.27

-4.33

GTKPCDVP

14.75

-3.07

-1.13
P38266

QPPVPVRM

7.45

-5.64

-3.70

VPILPPRN

8.57

-7.04

-5.11

GSITPPRP

9.15

-6.33

-4.39
P25333

AITPAPTP

13.78

-2.71

-0.77

TPAPTPTA

14.30

-5.39

-3.45

YPEGAPTS

14.77

-4.14

-2.20
P16603

PSTPVIMI

11.68

-3.07

-1.13

PNPELPDA

11.78

-3.76

-1.82

SNPSTPVI

12.29

-4.35

-2.41
P39692

SPKQPVIM

11.99

-5.13

-3.19

LPPSPKQP

12.51

-4.17

-2.23

PKQPVIMS

12.81

-4.70

-2.77
P38872

GTLPLPNP

12.82

-5.51

-3.57

LPNLYPHG

13.67

-4.35

-2.41

TLPLPNPY

13.81

-2.61

-0.67
P17555

PPPRPKKP

10.34

-4.21

-2.27

GPPPRPKK

10.58

-7.23

-5.29

KSGPPPRP

10.61

-4.73

-2.80
Q12344

SPPLPPRQ

8.86

-5.35

-3.41

SPKLPPRG

10.23

-6.29

-4.36

SSPPLPPR

10.86

-6.34

-4.40
P38289

EDPENPSF

10.42

-3.07

-1.13

VPTNDPSG

13.42

-5.00

-3.06

DPENPSFI

14.88

-2.67

-0.73
Q03780

SRPPPPPM

8.25

-6.68

-4.74

APDIPPRS

9.60

-5.22

-3.28

PPPPPMDM

9.68

-7.61

-5.68
P53316

MMPMFPSF

10.48

-5.28

-3.35

PQVPPVPY

11.49

-5.07

-3.14

VPYIIPPQ

11.67

-6.27

-4.33
P32190

PSTAPARE

12.57

-1.78

0.16

LRRPSTAP

13.67

-3.88

-1.94

RRPSTAPA

13.70

-1.14

0.80
Q12389

DPSQGPAA

15.00

-3.44

-1.50

LEDPSQGP

16.11

-2.37

-0.44

PSQGPAAN

16.23

-1.90

0.04
P13186

NNIPLTPL

10.51

-4.98

-3.05

PEREPPTY

11.06

-4.62

-2.69

RPPIPAAL

11.77

-3.89

-1.96
P12630

NPFCLPNS

12.24

-6.26

-4.32

SSNPFCLP

14.99

-2.10

-0.17

SNPFCLPN

15.30

-3.63

-1.69
P39940

DDPRLPSS

9.85

-6.26

-4.32

TWDDPRLP

10.69

-3.63

-1.69

DPRLPSSL

12.02

-4.49

-2.56
P04051

NPAMLPGS

12.60

-5.91

-3.98

SLPHFPKN

13.74

-4.88

-2.94

LPHFPKNS

14.08

-3.46

-1.52
P43603

TAPTSPST

14.13

-3.00

-1.06

RFTAPTSP

15.38

-3.47

-1.54

APTSPSTS

16.43

-0.86

1.08
P15891

PPPPPRRA

8.43

-5.98

-4.04

APPPPPRR

9.14

-7.27

-5.33

PPPPRRAT

10.13

-5.91

-3.98
P07278

TPPLPMHF

9.43

-6.06

-4.13

STPPLPMH

11.04

-4.50

-2.56

TSTPPLPM

13.66

-1.47

0.47
P06777

IPNEPDDI

12.70

-2.53

-0.59

PNEPDDIE

13.93

-1.76

0.18

LIPNEPDD

16.11

-0.77

1.17
P27999

SDPTLPRS

8.71

-5.98

-4.04

DPTLPRSD

13.10

-5.94

-4.01
Q12532

PFKPYING

14.35

-2.80

-0.86
Q12168

PPPLPPRA

9.19

-4.81

-2.87

DDPYFPQF

9.46

-5.53

-3.60

GPPPLPPR

10.15

-8.32

-6.38
Q04322

DQAPLDRP

8.85

-8.35

-6.41

SPPLPPRA

9.15

-6.16

-4.22

APLDRPQL

10.04

-6.75

-4.81
P08458

PKRKPPKL

8.89

-7.38

-5.45

LPKRKPPK

12.50

-8.71

-6.78

NLPKRKPP

12.61

-4.04

-2.11
Q02209

KGPESKPN

14.29

-1.94

-0.00

GPESKPNV

14.64

-6.28

-4.35
P47029

KGPKLPNL

9.29

-7.38

-5.45

LPRDPPSY

9.44

-6.54

-4.61

KHPTPPSL

10.89

-4.87

-2.94
P32793

GPTHPSNM

13.16

-2.51

-0.57

HGPTHPSN

13.51

-4.36

-2.43
P36006

IPPPPPPM

8.86

-6.74

-4.80

GQPKDPKF

9.32

-5.72

-3.78

ANIPIPPP

10.38

-6.69

-4.76
P32875

TPSKPDPM

11.40

-5.97

-4.04

SKPDPMEP

11.82

-3.98

-2.04

PSKPDPME

12.54

-2.77

-0.83
Q08412

KWQPLPPE

8.93

-6.63

-4.70

LPTQPVRK

11.23

-6.33

-4.39

VPPQLPTR

11.61

-6.58

-4.64
Q06440

DRTPKVEP

14.48

-5.49

-3.56

TPKVEPSK

14.68

-6.39

-4.46
Q12496

IPKKRPFL

9.32

-6.98

-5.04

SNIPKKRP

11.04

-6.98

-5.04

NIPKKRPF

11.57

-6.38

-4.45
P26570

TPLNSPGL

12.38

-6.69

-4.76

MEPKSPIL

12.45

-2.83

-0.90

WSDPTDSP

13.15

-2.35

-0.42
P31374

TPDDLPPL

8.27

-7.71

-5.78

EQPRLPST

8.77

-7.19

-5.26

ISPERPSF

9.05

-3.80

-1.86
P38237

NDPFVPPP

11.79

-3.67

-1.73

PPPNVPKK

12.02

-7.92

-5.98

DPFVPPPN

12.39

-5.35

-3.41
P34223

SPAEVPKN

13.03

-5.64

-3.70

TDPSDPNS

13.54

-1.54

0.40

MPDNEPKQ

14.32

-6.05

-4.12
P53118

NPHDLPSH

10.39

-6.43

-4.49

PHDLPSHL

13.84

-2.99

-1.06

VENPHDLP

14.46

-3.65

-1.71
P32389

NHPFEPNF

12.32

-3.90

-1.96

HPFEPNFM

13.13

-4.24

-2.31

SPSQFPAD

14.78

-3.59

-1.65
P53933

TRRRPPPP

8.51

-6.02

-4.08

RRPPPPPI

9.23

-4.80

-2.86

RRRPPPPP

9.67

-5.57

-3.64
P32790

PPIKPPRP

8.44

-6.40

-4.46

APAPLDPF

8.98

-8.18

-6.24

IKPPRPTS

10.91

-3.97

-2.04
P33400

SPQILPPL

8.71

-7.38

-5.45

QPPNAPSY

10.42

-5.77

-3.83

LPPLPVGI

12.04

-3.58

-1.65
P23293

SRPSHPQF

9.46

-7.63

-5.70

AIPRGPKK

12.09

-3.72

-1.79

HPQFPISP

12.87

-4.49

-2.56
Q04439

PAPPPPGM

10.24

-7.24

-5.30

SKPKEPMF

10.70

-5.61

-3.68

KKPAPPPP

10.88

-5.17

-3.23
P33338

PARTPART

11.54

-3.40

-1.46

ARTPARTP

11.75

-4.62

-2.69

TPTPTPPV

11.90

-5.84

-3.90
Q12446

PPPPPMRT

8.44

-4.87

-2.94

APPPPPRA

8.64

-5.32

-3.39

PPPPPRRG

8.90

-5.85

-3.91
P22219

SPGETPYL

12.53

-5.55

-3.61

VSPGETPY

14.23

-2.29

-0.35
P53220

NKPKPLWP

14.87

-3.30

-1.36
Q12373

SKRPLSQP

11.46

-5.72

-3.78

KRPLSQPT

13.72

-1.76

0.18

RPLSQPTT

14.37

-6.28

-4.35
P41695

HETPVKPS

13.66

-2.42

-0.48

ETPVKPSL

13.88

-4.50

-2.56

AHETPVKP

14.84

-3.83

-1.90
Q00916

LFKPRPPL

9.06

-6.37

-4.44

FKPRPPLS

10.33

-5.41

-3.48

YKRPTDYP

11.33

-4.62

-2.69
P53901

NSPKLPPL

8.28

-4.54

-2.61

AMRPIPPL

8.40

-8.48

-6.54

NQPPLPPI

8.90

-6.21

-4.28
P38990

PSPIRPVL

9.57

-5.33

-3.40

NQPSPIRP

9.62

-2.30

-0.36

QPSPIRPV

10.74

-5.53

-3.60
P47110

TPPRKPSP

11.76

-6.77

-4.83

TSTPPRKP

12.30

-2.36

-0.42

SKPNSPKE

12.91

-4.02

-2.08
P10566

IPMDLPDY

9.16

-7.82

-5.88

RPIPAIPM

9.44

-5.24

-3.31

IPAIPMDL

11.82

-5.67

-3.73
P25693

RPIPTIKP

11.60

-5.37

-3.44
Q07821

SQRPGKKP

12.66

-5.50

-3.56
P25558

LPNTPRSI

11.50

-6.93

-4.99

ELPNTPRS

11.79

-5.80

-3.86

KSPVKKPM

11.93

-4.10

-2.16
P40325

PWTYPPRF

4.44

-6.44

-4.51

QPPRPPRP

6.61

-6.82

-4.88

VQPGDPRL

6.98

-4.93

-2.99
P38750

LPHNLPHN

11.08

-6.17

-4.23

PPILPRTT

11.98

-4.70

-2.77

APASSPAY

12.35

-5.49

-3.56
P37370

AAPPLPTF

8.25

-5.88

-3.94

SAPPIPGM

8.96

-7.01

-5.07

PPPPPPAL

9.59

-7.89

-5.96
Q08446

SHSPISPL

13.15

-4.33

-2.40

SSHSPISP

13.76

-1.54

0.40

HSPISPLK

13.80

-2.67

-0.73
P39743

YSNPLTSP

13.23

-4.22

-2.28

SNPLTSPV

14.94

-1.80

0.14

NPLTSPVA

15.02

-4.55

-2.61
P47129

PPLLPPRN

9.69

-5.51

-3.57

GPPLLPPR

10.52

-8.29

-6.35

NRKPNPPP

10.92

-5.78

-3.85
P53169

MPTLPPRP

9.18

-4.26

-2.32

SVPIMPTL

11.47

-5.32

-3.39

NSVPIMPT

11.65

-5.24

-3.31

 


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