ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-7.PDB
Scoring matrix: RVS167_FYN-SSH-7_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 12.98
Foldx random average score for Saccharomyces cerevisiae: 10.728

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1617232
Proteins after disorder filtering: 4683
 Total fragments: 80339
Proteins after pattern filtering: 2245
 Total fragments: 15045
Proteins after MINT filtering: 71
 Total fragments: 992


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

12.98

-3.15

0.00
Best peptides

MRPLRPWR

0.00

-7.59

-4.44
         
Interactors      
P38140

QPDLPPRK

6.89

-7.82

-4.67

PDLPPRKI

7.15

-7.86

-4.71

NIPPHPYP

7.70

-5.51

-2.36
Q06604

PPSPPAKR

6.77

-7.72

-4.57

EKPLLPTR

6.92

-5.91

-2.76

KPAPPVSR

7.67

-6.13

-2.98
Q12365

IVPREPLR

7.11

-6.60

-3.45

IPFIPPQE

7.34

-6.99

-3.84

QIPFIPPQ

8.04

-5.84

-2.69
P40072

TPSASPML

8.32

-3.71

-0.56

PSASPMLD

9.62

-5.19

-2.04

PTTKPGTN

10.64

-5.34

-2.19
P40956

TPPLPRRR

7.30

-7.65

-4.50

TSTPPLPR

8.81

-5.15

-2.00

TTSTPPLP

9.01

-4.57

-1.42
Q06833

RRPSQPLN

6.64

-5.17

-2.02

RPVPRRPS

7.67

-6.35

-3.20

RRPVPRRP

8.52

-8.67

-5.52
P40032

FPSILPNV

7.29

-3.98

-0.83

RLFPSILP

8.28

-5.75

-2.60

ILPNVPHS

8.55

-3.15

0.00
P32628

EPPIAPES

9.43

-5.40

-2.25

PPIAPESA

10.48

-4.62

-1.47
Q12242

TKPCDVPN

9.63

-3.59

-0.44

PCDVPNNG

9.67

-5.16

-2.01

KPCDVPNN

9.73

-4.42

-1.27
P38266

MPPPKPFR

3.97

-9.58

-6.43

QPPPKPFR

4.92

-8.57

-5.42

KPPVVPKK

5.77

-7.07

-3.92
P25333

ITPAPTPT

9.96

-5.02

-1.87

TPAPTPTA

10.39

-2.67

0.48

YPEGAPTS

10.62

-3.14

0.01
P53169

IMPTLPPR

6.82

-5.76

-2.61

MPTLPPRP

7.41

-8.93

-5.78

VPIMPTLP

8.29

-7.59

-4.44
P39692

VMKLPPSP

6.17

-6.61

-3.46

KLPPSPKQ

6.48

-5.30

-2.15

MKLPPSPK

7.13

-6.43

-3.28
P38872

TLPLPNPY

6.47

-6.27

-3.12

CLPNLYPH

9.57

-4.81

-1.66

NCLPNLYP

10.58

-3.39

-0.24
P17555

GPPPRPKK

6.68

-6.61

-3.46

PPPRPKKP

7.37

-7.50

-4.35

PRPKKPST

8.13

-5.00

-1.85
Q12344

SPPLPPRQ

7.99

-6.93

-3.78

PLPPRQNV

8.04

-6.16

-3.01

TSPKLPPR

8.20

-3.71

-0.56
P38289

DPENPSFI

9.03

-5.50

-2.35

PENPSFIN

9.11

-4.52

-1.37

VPTNDPSG

9.90

-3.40

-0.25
Q03780

RPPPPPMD

5.75

-7.41

-4.26

KRSRPPPP

6.70

-5.61

-2.46

SRPPPPPM

6.86

-4.78

-1.63
P53316

MPMFPSFG

5.42

-7.45

-4.30

VPPVPYII

6.22

-7.10

-3.95

QVPPVPYI

6.61

-6.27

-3.12
P32190

RRPSTAPA

9.97

-2.59

0.56

RPSTAPAR

10.28

-3.87

-0.72
P13186

RPPIPAAL

7.37

-6.57

-3.42

IPMSPNYG

7.73

-3.89

-0.74

NIPLTPLA

7.87

-3.88

-0.73
P12630

PFCLPNSN

9.45

-4.17

-1.02

NPFCLPNS

10.16

-2.16

0.99
P39940

WDDPRLPS

6.67

-6.08

-2.93

PRLPSSLD

7.85

-4.57

-1.42

DPRLPSSL

8.78

-4.48

-1.33
P04051

DRSLPHFP

5.97

-6.74

-3.59

RSLPHFPK

8.90

-3.90

-0.75

PHFPKNSK

9.11

-4.65

-1.50
P43603

APTSPSTS

10.62

-3.46

-0.31
P15891

TPEKKPKE

7.15

-5.39

-2.24

QPPLPSRN

7.54

-7.22

-4.07

KEPVKTPS

7.69

-5.86

-2.71
P07278

TPPLPMHF

5.95

-5.31

-2.16

STPPLPMH

7.32

-6.80

-3.65

KTSTPPLP

8.18

-5.43

-2.28
P06777

PNEPDDIE

9.47

-6.40

-3.25

IPNEPDDI

10.24

-2.87

0.28
P27999

DPTLPRSD

9.04

-5.05

-1.90

IGSDPTLP

9.39

-6.02

-2.87

PTLPRSDR

9.69

-6.24

-3.09
P47029

PRDPPSYK

5.16

-6.79

-3.64

HPTPPSLK

7.47

-6.90

-3.75

GPKLPNLP

7.51

-6.82

-3.67
Q12168

NRGPPPLP

6.79

-6.65

-3.50

QHPVPKPN

6.82

-5.19

-2.04

IPPPVPNR

7.41

-5.70

-2.55
Q04322

QAPLDRPQ

7.19

-4.22

-1.07

PPTLPPRR

8.06

-7.84

-4.69

TSPPLPPR

8.08

-3.26

-0.11
P08458

PKRKPPKL

7.45

-6.38

-3.23

NLPKRKPP

8.48

-5.67

-2.52

TNLPKRKP

8.65

-7.66

-4.51
Q02209

YKGPESKP

8.50

-5.86

-2.71

PESKPNVN

8.59

-6.57

-3.42

KGPESKPN

10.43

-2.18

0.97
Q12496

IPKKRPFL

5.19

-8.36

-5.21

PSNIPKKR

6.74

-6.47

-3.32

IPSNIPKK

7.37

-3.70

-0.55
P32793

PTHPSNMS

9.76

-4.12

-0.97

GPTHPSNM

10.58

-4.51

-1.36
P36006

PPPPPPMG

6.39

-7.87

-4.72

IPPPPPPM

7.09

-5.64

-2.49

QPKDPKFE

7.46

-6.59

-3.44
P32875

PSKPDPME

7.87

-5.48

-2.33

KPDPMEPE

7.87

-5.04

-1.89

TPSKPDPM

8.74

-4.07

-0.92
Q08412

WQPLPPEP

6.94

-5.33

-2.18

QPLPPEPL

7.90

-5.17

-2.02

PLPPEPLD

8.06

-5.71

-2.56
Q06440

DRTPKVEP

9.49

-2.91

0.24

RTPKVEPS

9.81

-5.17

-2.02

TPKVEPSK

9.90

-2.59

0.56
P38750

PHNLPHNH

6.96

-4.82

-1.67

PPILPRTT

7.67

-7.52

-4.37

PASSPAYT

9.20

-4.93

-1.78
P26570

MEPKSPIL

6.21

-6.27

-3.12

TPSKPNLE

7.20

-6.31

-3.16

EPKSPILK

8.23

-6.12

-2.97
P31374

PDDLPPLK

4.53

-8.59

-5.44

SPERPSFR

6.42

-7.50

-4.35

TKPPPPLD

6.58

-5.83

-2.68
P38237

PPNVPKKD

7.67

-6.72

-3.57

PPPNVPKK

8.24

-6.41

-3.26

IPSKPENT

8.29

-4.43

-1.28
P34223

MPDNEPKQ

7.50

-5.69

-2.54

SPAEVPKN

8.91

-4.52

-1.37

QPMPDNEP

9.37

-5.23

-2.08
P53118

PHDLPSHL

5.89

-5.12

-1.97

VENPHDLP

7.05

-5.20

-2.05

NPHDLPSH

10.56

-2.50

0.65
P32389

MGSPSQFP

8.25

-6.08

-2.93

HPFEPNFM

8.88

-6.28

-3.13

NHPFEPNF

9.11

-3.68

-0.53
P53933

RRPPPPPI

6.15

-5.57

-2.42

RPPPPPIP

6.73

-7.25

-4.10

RRRPPPPP

7.34

-6.11

-2.96
P32790

PAPLDPFK

5.83

-5.98

-2.83

IKPPRPTS

7.25

-5.14

-1.99

AMPARPTA

7.58

-7.20

-4.05
P33400

ILPPLPVG

7.06

-4.92

-1.77

PQILPPLP

7.09

-7.41

-4.26

PPNAPSYQ

7.85

-6.63

-3.48
P23293

RPSHPQFP

7.70

-8.23

-5.08

KVPLPLGP

8.30

-5.68

-2.53

VPLPLGPQ

8.34

-3.87

-0.72
Q04439

APPPPGMQ

6.84

-7.30

-4.15

KPKEPMFE

7.28

-6.76

-3.61

KPAPPPPG

7.44

-6.02

-2.87
P33338

TPTPPVVA

8.20

-5.51

-2.36

VTPARTPA

9.02

-5.08

-1.93

RTPARTPT

9.49

-5.05

-1.90
Q12446

KHSLPPLP

4.20

-7.54

-4.39

VPPPPPMR

4.50

-9.31

-6.16

NRPLPQLP

5.29

-6.58

-3.43
P22219

NPDFPYNN

8.83

-5.10

-1.95

PGETPYLI

9.11

-5.93

-2.78

SPGETPYL

9.94

-3.15

0.00
P53220

NKPKPLWP

7.29

-7.57

-4.42
Q12373

KRPLSQPT

6.48

-4.90

-1.75

RPLSQPTT

10.27

-2.66

0.49

SKRPLSQP

10.51

-5.29

-2.14
P41695

TPVKPSLT

7.20

-5.91

-2.76

AHETPVKP

8.49

-5.54

-2.39

ETPVKPSL

10.07

-3.63

-0.48
Q00916

PRPPLSYK

5.40

-6.53

-3.38

FKPRPPLS

6.02

-6.54

-3.39

KRPTDYPY

7.42

-4.07

-0.92
P53901

MRPIPPLP

3.28

-8.44

-5.29

QPPLPPIP

5.14

-6.99

-3.84

SPKLPPLP

5.86

-6.96

-3.81
P38990

PSPIRPVL

6.95

-7.69

-4.54

VSSVPNLP

7.56

-6.46

-3.31

VPNLPSAP

7.64

-5.61

-2.46
P47110

TSTPPRKP

8.32

-6.61

-3.46

STPPRKPS

8.99

-4.91

-1.76

TPPRKPSP

9.04

-4.41

-1.26
P10566

TRPIPAIP

5.65

-6.46

-3.31

IPAIPMDL

8.07

-3.47

-0.32

PIPAIPMD

8.42

-6.91

-3.76
P25693

RPIPTIKP

9.51

-5.48

-2.33
P25558

SPVKKPMT

7.22

-6.01

-2.86

RHPKSPVK

7.48

-3.48

-0.33

KSPVKKPM

7.89

-5.50

-2.35
P40325

RPPPRPQQ

6.98

-7.26

-4.11

PRPPRPAA

7.03

-5.97

-2.82

PRPPPRPQ

7.17

-6.72

-3.57
P37370

MPKPRPFQ

4.11

-9.82

-6.67

APPLPTFS

5.65

-7.41

-4.26

APPIPGMG

6.29

-7.54

-4.39
Q08446

HSPISPLK

7.80

-4.48

-1.33

SHSPISPL

8.59

-3.64

-0.49
P39743

YSNPLTSP

9.79

-3.17

-0.02

SNPLTSPV

9.93

-3.29

-0.14

NPLTSPVA

10.63

-1.84

1.31
P47129

KPNPPPNR

6.87

-6.72

-3.57

GPPLLPPR

7.32

-4.73

-1.58

TLPNRKPN

8.35

-5.34

-2.19
P16603

NPSTPVIM

8.61

-4.76

-1.61

PSTPVIMI

8.67

-6.44

-3.29

FRLPSNPS

8.88

-3.76

-0.61

 


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