ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-6.PDB
Scoring matrix: RVS167_FYN-SSH-6_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 15.21
Foldx random average score for Saccharomyces cerevisiae: 18.303

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 2102374
Proteins after disorder filtering: 4694
 Total fragments: 170115
Proteins after pattern filtering: 2326
 Total fragments: 24751
Proteins after MINT filtering: 72
 Total fragments: 1350


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

15.21

-0.51

0.00
Best peptides

RPRIPRIPPK

0.00

-6.02

-5.51
         
Interactors      
P38140

QPDLPPRKIM

5.32

-6.61

-6.10

PDLPPRKIMI

6.76

-8.46

-7.95

MNIQPDLPPR

7.49

-3.86

-3.35
Q06604

KPLLPTRPNK

5.81

-6.80

-6.29

YSNIPSSKPA

6.11

-4.87

-4.36

GPRMPSRGRP

6.48

-5.57

-5.06
Q12365

VPREPLRNEP

7.04

-7.11

-6.60

VKDIPGKFPS

7.19

-5.14

-4.63

IPFIPPQEDD

7.21

-5.77

-5.26
P40072

LDAAPPTTKP

8.71

-4.19

-3.68

DAAPPTTKPG

10.14

-3.53

-3.02

PTTKPGTNSK

10.51

-4.08

-3.57
P40956

TPPLPRRRAT

5.01

-8.08

-7.57

RFWNPKNVPF

6.83

-4.55

-4.04

PKNVPFPFDG

9.68

-5.56

-5.05
Q06833

RRPVPRRPSQ

3.31

-8.26

-7.75

RPSQPLNTLS

6.62

-4.45

-3.94

VPRRPSQPLN

7.21

-6.40

-5.89
P40032

LRLFPSILPN

5.65

-6.05

-5.54

LPNVPHSDPS

6.27

-4.76

-4.25

RLFPSILPNV

8.83

-4.00

-3.49
P32628

PPIAPESATT

9.41

-3.61

-3.10

EPPIAPESAT

10.92

-4.77

-4.26

PIAPESATTP

18.16

2.93

3.44
Q12242

PCDVPNNGDQ

10.14

-5.45

-4.94

GTKPCDVPNN

12.06

-1.46

-0.95

KPCDVPNNGD

14.75

0.61

1.12
P38266

YPIEPSLDST

5.19

-6.80

-6.29

FPPPPLKPGQ

5.43

-6.61

-6.10

RNVEPSLVPQ

5.66

-5.49

-4.98
P25333

YPEGAPTSGA

10.49

-3.76

-3.25

TAITPAPTPT

10.97

-4.44

-3.93

PEGAPTSGAL

11.41

-4.66

-4.15
P16603

NFRLPSNPST

6.60

-6.61

-6.10

NPSTPVIMIG

7.34

-6.10

-5.59

NPELPDAPPV

7.91

-4.29

-3.78
P39692

LPPSPKQPVI

7.74

-5.03

-4.52

VMKLPPSPKQ

7.74

-3.78

-3.27

SPKQPVIMSG

8.01

-3.89

-3.38
P38872

INCLPNLYPH

8.44

-4.71

-4.20

HGTLPLPNPY

8.59

-2.74

-2.23

PNLYPHGTLP

11.27

-4.32

-3.81
P17555

RPKKPSTLKT

5.45

-5.86

-5.35

KSGPPPRPKK

6.93

-7.59

-7.08

PPPRPKKPST

7.54

-6.47

-5.96
Q12344

PPLPPRQNVA

6.58

-6.57

-6.06

SPKLPPRGKQ

6.81

-4.41

-3.90

SPPLPPRQNV

7.14

-5.98

-5.47
P38289

MYDVPTNDPS

6.77

-4.23

-3.72

DPENPSFINY

9.26

-4.62

-4.11

PENPSFINYR

11.61

-4.30

-3.79
Q03780

RPPPPPMDMK

3.36

-7.14

-6.63

APDIPPRSPN

5.35

-4.99

-4.48

RSRPPPPPMD

6.94

-7.47

-6.96
P53316

MPMFPSFGFI

5.78

-6.39

-5.88

VPPVPYIIPP

5.87

-6.99

-6.48

PYIIPPQNPA

6.96

-6.04

-5.53
P32190

GLRRPSTAPA

8.22

-4.32

-3.81

RPSTAPARET

9.72

-4.29

-3.78

PSTAPARETP

10.13

-4.95

-4.44
Q12389

LLEDPSQGPA

8.46

-4.34

-3.83

PSQGPAANGR

13.38

-3.29

-2.78

LEDPSQGPAA

13.55

-3.09

-2.58
P13186

RPPIPAALPP

5.62

-5.56

-5.05

QNNIPLTPLA

6.47

-4.73

-4.22

QEPLPEREPP

7.41

-5.43

-4.92
P12630

PFCLPNSNTS

9.36

-5.89

-5.38

DSSNPFCLPN

11.40

-3.33

-2.82

SNPFCLPNSN

12.10

0.00

0.51
P39940

TWDDPRLPSS

7.47

-5.75

-5.24

DPRLPSSLDQ

7.66

-4.16

-3.65

PSSSPHSQAP

11.59

-2.38

-1.87
P04051

LPHFPKNSKT

6.28

-8.21

-7.70

DRSLPHFPKN

7.50

-5.37

-4.86

PAMLPGSSNG

10.03

-5.02

-4.51
P43603

RFTAPTSPST

6.71

-4.45

-3.94

APTSPSTSSP

9.19

-4.13

-3.62

GRFTAPTSPS

11.39

-3.59

-3.08
P15891

RRATPEKKPK

5.85

-5.41

-4.90

PPPPPRRATP

6.18

-8.16

-7.65

APPPPPRRAT

6.37

-7.62

-7.11
P07278

KTSTPPLPMH

9.29

-3.51

-3.00

TSTPPLPMHF

9.81

-3.63

-3.12
P06777

IPNEPDDIET

9.62

-4.60

-4.09

PNEPDDIETS

14.56

1.07

1.58

LIPNEPDDIE

17.49

2.03

2.54
P27999

DPTLPRSDRE

6.47

-7.48

-6.97

IGSDPTLPRS

11.74

-3.07

-2.56

QDIGSDPTLP

14.60

-0.89

-0.38
P47029

HPTPPSLKAS

5.03

-6.08

-5.57

YDGHPASFPK

6.80

-4.87

-4.36

SSILPRDPPS

7.59

-4.65

-4.14
Q12168

NRGPPPLPPR

6.66

-5.35

-4.84

PPPLPPRANV

7.09

-6.08

-5.57

PPPVPNRPGG

7.59

-7.63

-7.12
Q04322

SSTPPTLPPR

8.72

-4.61

-4.10

NDQAPLDRPQ

8.81

-4.22

-3.71

GNATPSKSPT

9.19

-4.95

-4.44
P08458

MTNLPKRKPP

7.00

-6.19

-5.68

PKRKPPKLQG

7.92

-5.52

-5.01

QTVTPITNPS

10.29

-3.20

-2.69
Q02209

PESKPNVNFM

9.94

-6.10

-5.59

IYKGPESKPN

10.86

-3.57

-3.06

YKGPESKPNV

12.65

0.27

0.78
Q12496

PSNIPKKRPF

7.06

-5.61

-5.10

PEIPSNIPKK

10.66

-4.50

-3.99

IPSNIPKKRP

14.50

-0.34

0.17
P32793

GPTHPSNMSN

8.53

-4.21

-3.70

LGHGPTHPSN

11.22

-2.66

-2.15

SLGHGPTHPS

12.29

-2.66

-2.15
P36006

PPPPPPMGQP

7.21

-6.38

-5.87

QPKDPKFEAA

7.65

-5.81

-5.30

IPIPPPPPPM

7.94

-7.68

-7.17
P32875

TNRTPSKPDP

8.05

-2.84

-2.33

TPSKPDPMEP

9.27

-2.76

-2.25

NRTPSKPDPM

11.41

-2.91

-2.40
Q08412

PPQLPTRTKS

7.52

-7.40

-6.89

LPPEPLDTTP

8.18

-4.45

-3.94

DEDVPPQLPT

8.21

-7.31

-6.80
Q06440

KDRTPKVEPS

7.31

-3.55

-3.04

KKDRTPKVEP

13.83

-4.52

-4.01

DRTPKVEPSK

17.57

-1.80

-1.29
P38750

HLGLPHNLPH

5.61

-6.19

-5.68

PPILPRTTQD

6.63

-6.08

-5.57

LRSPPGVFPV

6.98

-5.14

-4.63
P26570

TPSKPNLEVN

8.04

-5.81

-5.30

DPSTPSKPNL

8.53

-5.31

-4.80

AYSTPLNSPG

9.14

-4.33

-3.82
P31374

QPRLPSTASS

6.15

-6.24

-5.73

RKTKPPPPLD

6.73

-8.01

-7.50

TPVFPNLDPT

6.76

-5.47

-4.96
P38237

NFQIPSKPEN

6.10

-5.72

-5.21

PFVPPPNVPK

6.93

-4.55

-4.04

FVPPPNVPKK

7.42

-5.61

-5.10
P34223

EQPMPDNEPK

8.45

-3.51

-3.00

PAEVPKNETP

9.69

-4.24

-3.73

GESSPAEVPK

11.62

-5.05

-4.54
P53118

PHDLPSHLGS

10.38

-5.44

-4.93

SVENPHDLPS

12.02

-3.59

-3.08

ESVENPHDLP

13.13

1.58

2.09
P32389

HPFEPNFMGS

6.14

-6.27

-5.76

FMGSPSQFPA

8.60

-4.46

-3.95

QNNHPFEPNF

9.02

-3.55

-3.04
P53933

RPPPPPIPST

3.15

-8.23

-7.72

RRRPPPPPIP

5.86

-9.14

-8.63

RRPPPPPIPS

6.49

-8.60

-8.09
P32790

PPIKPPRPTS

6.50

-7.47

-6.96

PPAMPARPTA

7.29

-5.99

-5.48

KPPRPTSTTS

8.83

-5.29

-4.78
P33400

PQILPPLPVG

7.63

-5.27

-4.76

HSTSPQILPP

7.70

-4.55

-4.04

YVQPPNAPSY

8.70

-5.14

-4.63
P23293

HPQFPISPSQ

5.73

-6.00

-5.49

RPSHPQFPIS

5.78

-5.03

-4.52

FPISPSQGQH

7.34

-5.46

-4.95
Q04439

APPPPGMQNK

6.88

-6.44

-5.93

PPPPPSSKPK

6.97

-6.81

-6.30

KPKEPMFEAA

7.31

-5.88

-5.37
P33338

TPTPPVVAEP

7.19

-4.95

-4.44

ARTPARTPTP

9.24

-5.58

-5.07

PARTPARTPT

9.30

-5.84

-5.33
Q12446

RPVPPPPPMR

5.62

-8.52

-8.01

PPPPPRRGPA

5.90

-6.51

-6.00

PFPIPEIPST

6.19

-5.77

-5.26
P22219

NPDFPYNNSN

7.24

-4.13

-3.62

SAVSPGETPY

12.32

-2.70

-2.19

AVSPGETPYL

13.51

-3.03

-2.52
P53220

TRNKPKPLWP

8.98

-2.79

-2.28
Q12373

GSKRPLSQPT

9.73

-2.80

-2.29

PLSQPTTSIG

10.02

-5.37

-4.86

KRPLSQPTTS

13.20

-2.75

-2.24
P41695

TPVKPSLTSN

6.98

-5.59

-5.08

AHETPVKPSL

10.39

-3.79

-3.28

HETPVKPSLT

13.34

-4.60

-4.09
Q00916

RLFKPRPPLS

5.39

-5.41

-4.90

FKPRPPLSYK

6.42

-6.29

-5.78

KPRPPLSYKR

7.01

-5.20

-4.69
P53901

QPPLPPIPTR

4.94

-7.34

-6.83

MRPIPPLPTE

5.31

-5.65

-5.14

LPPIPTRDDM

5.87

-7.65

-7.14
P38990

NQNLPKIPNS

5.95

-4.11

-3.60

VPNLPSAPSS

8.16

-4.88

-4.37

LPSAPSSTRL

8.26

-3.51

-3.00
P47110

TSTPPRKPSP

6.59

-6.22

-5.71

ATSTPPRKPS

9.84

-5.51

-5.00

KPNSPKETDS

9.87

-5.56

-5.05
P10566

TRPIPAIPMD

5.77

-4.92

-4.41

IPAIPMDLPD

8.57

-4.27

-3.76

RPIPAIPMDL

9.38

-5.40

-4.89
P25693

ENRPIPTIKP

13.58

1.88

2.39
P25558

LPNTPRSINV

6.78

-6.88

-6.37

HPKSPVKKPM

6.93

-6.13

-5.62

NPSQPVTENT

9.09

-3.71

-3.20
P40325

QPRPPPRPQQ

4.92

-8.14

-7.63

QPPRPPRPAA

6.25

-6.39

-5.88

NPSLPWTYPP

6.52

-3.79

-3.28
P37370

RPHMPSVRPA

3.79

-7.53

-7.02

APPIPDIPSS

5.68

-5.20

-4.69

APAVPSIPSS

6.07

-6.67

-6.16
Q08446

SSHSPISPLK

10.44

-3.00

-2.49

NSSHSPISPL

11.07

-2.24

-1.73
P39743

AYSNPLTSPV

9.59

-3.09

-2.58

PAYSNPLTSP

14.64

1.26

1.77

PNATIPEDNP

16.60

2.49

3.00
P47129

PLLPPRNTMK

6.33

-6.05

-5.54

KPNPPPNRSQ

6.40

-5.77

-5.26

PPLLPPRNTM

7.01

-5.20

-4.69
P53169

VPIMPTLPPR

6.63

-6.17

-5.66

ANSVPIMPTL

7.82

-5.50

-4.99

SPAQPSASLT

10.55

-4.07

-3.56

 


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