ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-5.PDB
Scoring matrix: RVS167_FYN-SSH-5_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.33
Foldx random average score for Saccharomyces cerevisiae: 16.393

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1398192
Proteins after disorder filtering: 4416
 Total fragments: 75552
Proteins after pattern filtering: 2270
 Total fragments: 17579
Proteins after MINT filtering: 72
 Total fragments: 975


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.33

-2.06

0.00
Best peptides

RINFPPPPHF

0.00

-8.46

-6.40
         
Interactors      
P38140

PMNIQPDLPP

9.41

-10.17

-8.11

NIQPDLPPRK

10.40

-8.79

-6.73

NIPPHPYPSS

11.74

-5.29

-3.23
Q06604

TMKNKPKPTP

8.18

-10.36

-8.30

RVKPAPPVSR

8.47

-9.40

-7.34

RYSNIPSSKP

9.20

-9.42

-7.36
Q12365

QIPFIPPQED

9.36

-8.08

-6.02

IVPREPLRNE

10.17

-7.72

-5.66

PGKFPSPLTK

11.02

-5.02

-2.96
P40072

LDAAPPTTKP

14.31

-6.03

-3.97

PSASPMLDAA

15.50

-3.97

-1.91
P40956

ARFWNPKNVP

7.82

-9.14

-7.08

RFWNPKNVPF

10.04

-7.86

-5.80

TTSTPPLPRR

10.19

-7.19

-5.13
Q06833

RRPSQPLNTL

10.72

-8.80

-6.74

NFPVPPSASN

10.82

-6.90

-4.84

PVPRRPSQPL

11.79

-8.25

-6.19
P40032

LFPSILPNVP

9.33

-9.13

-7.07

ILPNVPHSDP

10.00

-9.20

-7.14

GLRLFPSILP

10.73

-8.92

-6.86
P32628

PIAPESATTP

15.65

-6.57

-4.51
P22219

SSAVSPGETP

12.91

-5.58

-3.52

NPDFPYNNSN

16.00

-9.74

-7.68
P38266

IQNFQPPPKP

7.27

-10.93

-8.87

ANIMPPPKPF

7.47

-9.17

-7.11

RNNVEPPPPP

7.67

-8.78

-6.72
P25333

NTAITPAPTP

11.73

-7.46

-5.40

AITPAPTPTA

14.08

-4.92

-2.86

TAITPAPTPT

14.51

-4.49

-2.43
P16603

RLPSNPSTPV

11.34

-8.71

-6.65

PNPELPDAPP

12.70

-6.80

-4.74

FRLPSNPSTP

12.99

-8.41

-6.35
P39692

VMKLPPSPKQ

9.90

-7.22

-5.16

KLPPSPKQPV

11.49

-8.84

-6.78

MKLPPSPKQP

12.49

-7.57

-5.51
P38872

HGTLPLPNPY

7.77

-4.90

-2.84

PHGTLPLPNP

9.98

-8.50

-6.44

SINCLPNLYP

10.62

-7.60

-5.54
P17555

AAPAPPPPPP

9.33

-8.01

-5.95

GSKSGPPPRP

9.89

-8.18

-6.12

SKSGPPPRPK

10.35

-7.80

-5.74
Q12344

ATSTSPKLPP

10.53

-8.15

-6.09

PTTSSPPLPP

10.79

-8.32

-6.26

TTSSPPLPPR

11.10

-6.27

-4.21
P38289

HMYDVPTNDP

11.55

-8.45

-6.39

EDPENPSFIN

16.17

-3.98

-1.92
Q03780

KRSRPPPPPM

7.71

-10.56

-8.50

IKRSRPPPPP

8.26

-9.50

-7.44

SRPPPPPMDM

10.49

-10.69

-8.63
P53316

FIPQVPPVPY

6.12

1.73

3.79

MMPMFPSFGF

7.19

-10.28

-8.22

SFGFIPQVPP

7.85

-7.24

-5.18
P32190

SGLRRPSTAP

10.04

-5.39

-3.33

RRPSTAPARE

12.09

-6.88

-4.82

PSTAPARETP

14.47

-5.65

-3.59
Q12389

NLLEDPSQGP

11.79

-7.93

-5.87

LLEDPSQGPA

15.33

-5.88

-3.82
P13186

NIPLTPLATN

10.17

-7.07

-5.01

RNSSIPMSPN

11.34

-6.67

-4.61

SIPMSPNYGN

11.44

-6.78

-4.72
P12630

SNPFCLPNSN

12.00

-4.73

-2.67

MDSSNPFCLP

12.08

-7.80

-5.74

PFCLPNSNTS

15.83

-3.59

-1.53
P39940

TTWDDPRLPS

14.04

-3.65

-1.59

TTTWDDPRLP

14.52

-6.98

-4.92

PSSSPHSQAP

15.13

-5.57

-3.51
P04051

SLPHFPKNSK

8.71

-7.85

-5.79

FQDRSLPHFP

9.66

-8.05

-5.99

DRSLPHFPKN

12.99

-6.83

-4.77
P43603

QGRFTAPTSP

9.83

-8.37

-6.31

TAPTSPSTSS

14.72

-3.05

-0.99

GRFTAPTSPS

15.63

-4.86

-2.80
P15891

RSSAAPPPPP

8.67

-8.07

-6.01

KKSFTPSKSP

8.88

-8.51

-6.45

IISPKPFSKP

8.97

-9.64

-7.58
P07278

KTSTPPLPMH

10.39

-7.31

-5.25

TSTPPLPMHF

10.69

-5.92

-3.86
P06777

LIPNEPDDIE

10.23

-7.41

-5.35
P27999

SDPTLPRSDR

12.73

-3.85

-1.79

DIGSDPTLPR

13.23

-5.64

-3.58
P47029

ILPRDPPSYK

9.30

-9.81

-7.75

SLNLSPLGAP

9.36

-9.69

-7.63

ESSILPRDPP

10.53

-6.07

-4.01
Q12168

RGPPPLPPRA

9.09

-6.79

-4.73

TTNRGPPPLP

9.51

-9.39

-7.33

TNRGPPPLPP

10.12

-8.62

-6.56
P08458

VMTNLPKRKP

9.01

-10.15

-8.09

MTNLPKRKPP

10.38

-7.72

-5.66

NLPKRKPPKL

12.08

-6.43

-4.37
Q02209

KGPESKPNVN

12.74

-2.42

-0.36

GPESKPNVNF

15.79

-7.85

-5.79
Q12496

PSNIPKKRPF

11.74

-4.60

-2.54

IPSNIPKKRP

13.23

-9.39

-7.33

SNIPKKRPFL

15.73

-3.70

-1.64
P32793

HGPTHPSNMS

12.10

-2.58

-0.52

GHGPTHPSNM

13.17

-6.88

-4.82

SLGHGPTHPS

13.18

-5.12

-3.06
P36006

NIPIPPPPPP

6.13

-10.67

-8.61

ANIPIPPPPP

10.83

-6.94

-4.88

PMGQPKDPKF

11.02

-5.49

-3.43
P32875

RTPSKPDPME

11.90

-6.04

-3.98

KTNRTPSKPD

13.13

-7.10

-5.04

NRTPSKPDPM

13.17

-5.27

-3.21
Q08412

KKKWQPLPPE

8.99

-7.47

-5.41

KWQPLPPEPL

10.11

-8.07

-6.01

KKWQPLPPEP

10.59

-7.98

-5.92
Q06440

KKDRTPKVEP

10.01

-7.90

-5.84
P38750

SLRSPPGVFP

10.05

-8.86

-6.80

GLPHNLPHNH

10.15

-7.45

-5.39

HLGLPHNLPH

10.28

-7.17

-5.11
P26570

LLWSDPTDSP

11.06

-8.64

-6.58

TAYSTPLNSP

11.31

-7.01

-4.95

MEPKSPILKT

13.19

-5.05

-2.99
P31374

RKTKPPPPLD

9.01

-8.62

-6.56

FRKTKPPPPL

9.12

-10.58

-8.52

KTKPPPPLDF

9.25

-9.59

-7.53
P38237

NDPFVPPPNV

11.57

-6.27

-4.21

PFVPPPNVPK

11.65

-6.51

-4.45

DGTFPEPEVP

11.85

-6.24

-4.18
P34223

PGESSPAEVP

10.42

-5.82

-3.76

LEVTDPSDPN

13.29

-4.46

-2.40

QEQPMPDNEP

14.33

-5.29

-3.23
P53118

ENPHDLPSHL

12.24

-7.49

-5.43

ESVENPHDLP

13.48

-6.33

-4.27

SVENPHDLPS

14.40

-4.83

-2.77
P32389

NFMGSPSQFP

10.28

-7.04

-4.98

MQNNHPFEPN

10.48

-6.29

-4.23

NMQNNHPFEP

11.39

-6.56

-4.50
P53933

RTRRRPPPPP

6.98

-11.68

-9.62

RRRPPPPPIP

7.31

-12.61

-10.55

RVAPPPLPNR

8.45

-8.12

-6.06
P32790

SSAPAPLDPF

11.27

-4.80

-2.74

DEEGPPPAMP

12.42

-7.07

-5.01

LPPIKPPRPT

13.16

-9.10

-7.04
P33400

TSYVQPPNAP

11.23

-6.93

-4.87

SHSTSPQILP

11.63

-7.29

-5.23

SYVQPPNAPS

12.45

-4.26

-2.20
P23293

PLPLGPQSRY

8.29

-9.54

-7.48

AIPRGPKKDD

9.53

-8.77

-6.71

KTAIPPPAAP

9.72

-9.03

-6.97
Q04439

NIPPPPPPPP

7.42

-10.79

-8.73

RHSKKPAPPP

7.65

-8.25

-6.19

QANIPPPPPP

8.42

-8.84

-6.78
P33338

LSWSGPLTPP

10.41

-7.58

-5.52

PLSWSGPLTP

12.10

-9.20

-7.14

PARTPARTPT

14.84

-4.04

-1.98
Q12446

RGPAPPPPPH

5.60

-5.52

-3.46

RGPAPPPPPR

6.27

-7.19

-5.13

RLPAPPPPPR

6.47

-10.78

-8.72
Q04322

KNDQAPLDRP

9.13

-8.52

-6.46

HGNATPSKSP

9.67

-5.51

-3.45

SSSSTPPTLP

11.98

-6.07

-4.01
P53220

TRNKPKPLWP

11.50

-5.97

-3.91
Q12373

KRPLSQPTTS

15.26

-2.41

-0.35

GSKRPLSQPT

15.41

-4.37

-2.31
P41695

ETPVKPSLTS

14.72

-4.59

-2.53

LAHETPVKPS

14.81

-4.24

-2.18

HETPVKPSLT

16.31

-1.33

0.73
Q00916

LFKPRPPLSY

7.27

-9.15

-7.09

SRLFKPRPPL

8.75

-8.88

-6.82

FKPRPPLSYK

9.33

-9.29

-7.23
P53901

SGLNSPKLPP

8.68

-6.23

-4.17

MRPIPPLPTE

8.84

-6.58

-4.52

NYNQPPLPPI

9.64

-6.59

-4.53
P38990

RNQNLPKIPN

10.88

-6.42

-4.36

NLPSAPSSTR

11.00

-6.48

-4.42

SRNQNLPKIP

11.30

-8.14

-6.08
P47110

NGGSKPNSPK

10.61

-4.25

-2.19

PATSTPPRKP

10.99

-5.34

-3.28

SKPNSPKETD

12.36

-5.83

-3.77
P10566

PIPAIPMDLP

9.68

-9.41

-7.35

STRPIPAIPM

13.73

-6.79

-4.73
P25693

ENRPIPTIKP

15.57

-5.82

-3.76
Q07821

PDSQRPGKKP

13.52

-6.21

-4.15
P25558

RHPKSPVKKP

9.69

-8.37

-6.31

ELPNTPRSIN

11.35

-8.73

-6.67

KSPVKKPMTS

15.34

-4.95

-2.89
P40325

SLPWTYPPRF

5.93

-9.61

-7.55

PWTYPPRFYC

9.52

-6.21

-4.15

SSQPRPPPRP

10.10

-8.59

-6.53
P37370

LAPLPPPPPP

7.34

-9.72

-7.66

SMPAPPPPPP

7.44

-11.33

-9.27

PGHVPPPPVP

7.49

-7.61

-5.55
Q08446

NSSHSPISPL

14.25

-5.27

-3.21

NNSSHSPISP

14.99

-5.86

-3.80
P39743

PAYSNPLTSP

11.81

-6.95

-4.89

PNATIPEDNP

12.69

-6.70

-4.64

AYSNPLTSPV

16.31

-5.10

-3.04
P47129

RKPNPPPNRS

8.79

-8.05

-5.99

NRKPNPPPNR

10.86

-6.20

-4.14

TLPNRKPNPP

11.12

-9.18

-7.12
P53169

IMPTLPPRPY

7.09

-9.70

-7.64

PIMPTLPPRP

9.85

-10.10

-8.04

SVPIMPTLPP

11.71

-7.31

-5.25

 


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