ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-28.PDB
Scoring matrix: RVS167_FYN-SSH-28_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 14.93
Foldx random average score for Saccharomyces cerevisiae: 16.615

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1664602
Proteins after disorder filtering: 4539
 Total fragments: 83146
Proteins after pattern filtering: 2208
 Total fragments: 15808
Proteins after MINT filtering: 70
 Total fragments: 881


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

14.93

-2.10

0.00
Best peptides

RKPIWRPKRK

0.00

-6.46

-4.37
         
Interactors      
P38140

NIQPDLPPRK

10.74

-4.71

-2.61

QPDLPPRKIM

11.79

-10.20

-8.10

IPPHPYPSSN

12.80

-7.24

-5.14
Q06604

KPLLPTRPNK

7.92

-9.66

-7.56

KPTPPSPPAK

9.48

-8.37

-6.27

VKPAPPVSRS

10.26

-8.09

-5.99
Q12365

IPGKFPSPLT

13.73

-5.67

-3.57

PGKFPSPLTK

13.78

-5.79

-3.69

IPFIPPQEDD

14.16

-7.41

-5.31
P40072

APPTTKPGTN

14.05

-5.12

-3.02

NTPSASPMLD

14.52

-3.75

-1.65

PPTTKPGTNS

14.77

-4.07

-1.98
P40956

STPPLPRRRA

10.97

-8.39

-6.29

TPPLPRRRAT

11.06

-8.65

-6.55

PPLPRRRATT

11.33

-8.49

-6.39
Q06833

RRPVPRRPSQ

9.60

-10.88

-8.79

FPVPPSASNM

11.80

-9.14

-7.04

NFPVPPSASN

13.37

-6.19

-4.10
P40032

RLFPSILPNV

12.27

-6.95

-4.86

FPSILPNVPH

13.06

-8.82

-6.72

PSILPNVPHS

13.33

-5.09

-2.99
P32628

EPPIAPESAT

10.85

-6.17

-4.07

PPIAPESATT

11.89

-5.91

-3.81
Q12242

TKPCDVPNNG

14.44

-3.75

-1.65

GTKPCDVPNN

15.89

-5.50

-3.40
P38266

FLPPPKPFRH

7.13

-7.64

-5.54

IMPPPKPFRH

7.70

-7.92

-5.82

RAVPILPPRN

7.74

-8.06

-5.96
P25333

ITPAPTPTAS

11.78

-5.86

-3.77

AITPAPTPTA

13.54

-5.34

-3.24

DKYPEGAPTS

13.71

-3.67

-1.57
P16603

NPELPDAPPV

12.86

-6.37

-4.28

NPSTPVIMIG

13.93

-5.93

-3.83

RLPSNPSTPV

14.06

-4.07

-1.98
P39692

VMKLPPSPKQ

11.57

-6.44

-4.35

PPSPKQPVIM

13.77

-7.73

-5.63

LPPSPKQPVI

15.17

-8.34

-6.24
P38872

CLPNLYPHGT

14.94

-5.21

-3.11

HGTLPLPNPY

15.16

-4.21

-2.11

NCLPNLYPHG

15.19

-5.78

-3.69
P17555

KSGPPPRPKK

9.95

-7.81

-5.71

PPPAPPASVF

10.69

-7.79

-5.70

PPPPPAPPAS

11.31

-7.52

-5.42
Q12344

SPPLPPRQNV

11.52

-7.68

-5.58

TSSPPLPPRQ

11.73

-5.18

-3.08

PKLPPRGKQR

11.78

-7.56

-5.46
P38289

EDPENPSFIN

12.44

-3.94

-1.84

PTNDPSGILN

14.69

-4.84

-2.74

YDVPTNDPSG

15.08

-5.32

-3.23
Q03780

RPPPPPMDMK

7.42

-11.91

-9.81

DIPPRSPNRN

10.80

-6.67

-4.57

RSRPPPPPMD

10.94

-6.47

-4.38
P53316

PVPYIIPPQN

11.00

-5.57

-3.48

MMPMFPSFGF

11.32

-8.52

-6.42

WMMPMFPSFG

11.69

-5.64

-3.54
P32190

RRPSTAPARE

10.17

-6.91

-4.81

RPSTAPARET

11.58

-4.89

-2.79

LRRPSTAPAR

13.24

-5.76

-3.66
Q12389

EDPSQGPAAN

14.01

-4.73

-2.64

LEDPSQGPAA

14.49

-3.97

-1.88

DPSQGPAANG

15.95

-4.77

-2.67
P13186

NSSIPMSPNY

9.94

-4.83

-2.73

PLPEREPPTY

10.70

-7.05

-4.96

KAPSYVPNRV

11.62

-5.47

-3.37
P12630

PFCLPNSNTS

13.04

-4.97

-2.87

NPFCLPNSNT

15.01

-6.52

-4.42

SSNPFCLPNS

16.07

-5.81

-3.71
P39940

DPRLPSSLDQ

13.67

-5.31

-3.21

DDPRLPSSLD

15.04

-5.51

-3.41

WDDPRLPSSL

15.09

-7.26

-5.16
P04051

RSLPHFPKNS

10.52

-4.08

-1.98

DRSLPHFPKN

11.95

-7.32

-5.22

NPAMLPGSSN

13.20

-6.73

-4.63
P43603

RFTAPTSPST

12.36

-4.88

-2.78

FTAPTSPSTS

13.16

-4.38

-2.28
P15891

AAPPPPPRRA

9.36

-7.02

-4.92

QPPLPSRNVA

9.86

-9.56

-7.46

KTPSPAPAAK

10.18

-6.96

-4.87
P07278

KTSTPPLPMH

12.70

-7.79

-5.70

TSTPPLPMHF

12.90

-5.35

-3.25
P06777

IPNEPDDIET

13.35

-5.38

-3.28

LIPNEPDDIE

15.21

-5.44

-3.35
P27999

DPTLPRSDRE

9.67

-7.47

-5.38

PTLPRSDREC

14.10

-4.76

-2.66

IGSDPTLPRS

14.24

-6.70

-4.61
P47029

LSPLGAPGNS

12.02

-4.83

-2.73

KHPTPPSLKA

12.14

-6.45

-4.36

ILPRDPPSYK

12.43

-6.27

-4.17
Q12168

RGPPPLPPRA

8.10

-6.47

-4.38

PPPLPPRANV

10.62

-8.84

-6.74

GPPPLPPRAN

11.82

-6.86

-4.77
Q04322

TPPTLPPRRI

13.06

-8.79

-6.69

NATPSKSPTS

13.59

-3.03

-0.93

STPPTLPPRR

13.62

-5.75

-3.65
P08458

LPKRKPPKLQ

13.05

-7.75

-5.65

VTPITNPSSS

13.74

-4.90

-2.81

NLPKRKPPKL

15.74

-8.07

-5.97
Q02209

KGPESKPNVN

13.64

-3.87

-1.77

YKGPESKPNV

13.87

-5.87

-3.77

GPESKPNVNF

16.20

-7.84

-5.74
Q12496

EIPSNIPKKR

13.10

-5.91

-3.81

PSNIPKKRPF

14.47

-6.22

-4.13

PEIPSNIPKK

14.84

-6.05

-3.95
P32793

HGPTHPSNMS

15.98

-3.57

-1.47

PTHPSNMSNV

16.43

-6.71

-4.62
P36006

IPPPPPPMGQ

10.55

-8.34

-6.24

PIPPPPPPMG

11.33

-7.09

-4.99

PPPPPMGQPK

12.87

-7.74

-5.64
P32875

RTPSKPDPME

10.69

-4.89

-2.79

NRTPSKPDPM

16.46

-5.62

-3.52
Q08412

DVPPQLPTRT

11.45

-6.06

-3.96

PPQLPTRTKS

11.65

-7.99

-5.89

IELPTQPVRK

11.79

-6.83

-4.73
Q06440

DRTPKVEPSK

13.52

-6.46

-4.37

KDRTPKVEPS

14.81

-3.87

-1.77
P38750

RSPPGVFPVR

12.10

-8.05

-5.96

NAPASSPAYT

14.01

-2.84

-0.74

PPILPRTTQD

14.19

-6.77

-4.67
P26570

NVPDPSTPSK

12.57

-6.50

-4.40

EPKSPILKTN

12.66

-8.38

-6.29

STPLNSPGLS

13.51

-3.80

-1.70
P31374

FEQPRLPSTA

10.09

-6.86

-4.77

ISPERPSFRQ

11.13

-6.65

-4.55

KTKPPPPLDF

11.71

-6.38

-4.29
P38237

FVPPPNVPKK

8.45

-8.61

-6.51

FQIPSKPENT

12.45

-4.91

-2.81

NDPFVPPPNV

12.82

-4.67

-2.57
P34223

ESSPAEVPKN

13.99

-4.57

-2.48

EVTDPSDPNS

14.21

-5.12

-3.02

PMPDNEPKQG

14.26

-4.76

-2.66
P53118

NPHDLPSHLG

14.05

-5.25

-3.15

VENPHDLPSH

15.94

-7.94

-5.85
P32389

HPFEPNFMGS

13.88

-7.66

-5.56

PSQFPADATN

15.06

-3.92

-1.82

NNHPFEPNFM

15.28

-5.88

-3.78
P53933

RVAPPPLPNR

9.61

-9.94

-7.84

RRPPPPPIPS

9.80

-7.06

-4.96

PPPPIPSTQK

10.20

-8.69

-6.59
P32790

LPPIKPPRPT

10.15

-6.87

-4.78

IKPPRPTSTT

10.84

-6.88

-4.79

KPPRPTSTTS

10.97

-7.83

-5.73
P33400

YVQPPNAPSY

10.73

-7.45

-5.36

ILPPLPVGIS

11.95

-6.66

-4.56

SPQILPPLPV

12.87

-6.11

-4.02
P23293

LGAIPRGPKK

8.96

-7.01

-4.91

KVPLPLGPQS

9.82

-5.15

-3.06

IPPPAAPAGV

11.96

-6.83

-4.73
Q04439

RPSPPTAATR

8.10

-8.90

-6.80

PPPPPPPSSK

9.81

-8.69

-6.59

NNNIPTPPQN

10.34

-4.25

-2.15
P33338

RTPTPTPPVV

9.28

-5.64

-3.54

VTPARTPART

10.62

-5.79

-3.69

RTPARTPTPT

11.85

-5.71

-3.61
Q12446

LPAPPPPPRR

7.91

-9.25

-7.15

RPVPPPPPMR

7.96

-9.44

-7.34

RPLPQLPNRN

8.52

-7.29

-5.20
P22219

PDFPYNNSNY

16.28

-7.53

-5.44
Q12373

KRPLSQPTTS

9.92

-5.77

-3.67

SKRPLSQPTT

15.28

-5.15

-3.06

RPLSQPTTSI

15.75

-6.62

-4.53
P41695

ETPVKPSLTS

12.45

-4.35

-2.25

HETPVKPSLT

13.65

-5.30

-3.20

PVKPSLTSNA

15.29

-4.58

-2.48
Q00916

FKPRPPLSYK

10.24

-9.76

-7.66

RLFKPRPPLS

10.65

-6.76

-4.66

KPRPPLSYKR

11.04

-9.14

-7.04
P53901

NDPIILPPTF

5.81

-8.20

-6.10

MRPIPPLPTE

6.82

-8.94

-6.84

RPIPPLPTES

9.63

-7.62

-5.53
P38990

VPNLPSAPSS

12.05

-5.64

-3.54

NLPSAPSSTR

12.16

-5.61

-3.52

LPSAPSSTRL

13.23

-7.90

-5.80
P47110

KPNSPKETDS

13.90

-5.80

-3.70

STPPRKPSPV

14.94

-5.49

-3.40

ATSTPPRKPS

15.35

-4.13

-2.03
P10566

TRPIPAIPMD

12.82

-7.73

-5.63

IPAIPMDLPD

13.09

-5.71

-3.61

RPIPAIPMDL

13.66

-6.89

-4.79
P25558

KSPVKKPMTS

11.30

-5.35

-3.25

LPNTPRSINV

12.16

-6.46

-4.37

YNPSQPVTEN

14.53

-4.67

-2.57
P40325

RPPRPAANLA

9.63

-8.69

-6.59

PRPPPRPQQN

11.25

-7.28

-5.19

RPSTMPATSS

11.41

-6.79

-4.70
P37370

RPSPISPSIN

8.15

-7.80

-5.71

LPPPPPPSVA

8.58

-8.32

-6.22

APPIPNAPLS

9.16

-7.62

-5.53
Q08446

SSHSPISPLK

13.28

-4.59

-2.49
P39743

YSNPLTSPVA

10.99

-5.46

-3.36
P47129

RKPNPPPNRS

8.04

-8.69

-6.59

GPPLLPPRNT

10.35

-6.82

-4.72

PPLLPPRNTM

11.40

-9.99

-7.89
P53169

IMPTLPPRPY

13.34

-6.84

-4.74

SPAQPSASLT

14.90

-5.84

-3.74

VPIMPTLPPR

15.49

-10.11

-8.01

 


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