ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-26.PDB
Scoring matrix: RVS167_FYN-SSH-26_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 13.78
Foldx random average score for Saccharomyces cerevisiae: 9.620

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7178
 Total fragments: 1319902
Proteins after disorder filtering: 4384
 Total fragments: 65912
Proteins after pattern filtering: 2228
 Total fragments: 16304
Proteins after MINT filtering: 73
 Total fragments: 1060


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

13.78

-2.23

0.00
Best peptides

DRMPKRRPP

0.00

-7.57

-5.34
         
Interactors      
P38140

IQPDLPPRK

6.32

-7.71

-5.48

QPDLPPRKI

6.34

-6.36

-4.13

MNIQPDLPP

6.59

-5.77

-3.54
Q06604

PSPPAKRIP

3.22

-8.51

-6.28

KPKPTPPSP

4.94

-6.66

-4.43

SFEKGPRMP

5.07

-5.95

-3.72
Q12365

IVPREPLRN

5.93

-8.00

-5.77

KDIPGKFPS

6.19

-5.74

-3.51

VPREPLRNE

6.50

-6.65

-4.42
P40072

DAAPPTTKP

8.24

-5.15

-2.92

AAPPTTKPG

8.36

-6.69

-4.46

TPSASPMLD

8.60

-3.07

-0.84
P40956

STPPLPRRR

3.59

-7.87

-5.64

TPPLPRRRA

4.07

-7.02

-4.79

PPLPRRRAT

4.65

-7.82

-5.59
Q06833

NRRPVPRRP

2.58

-8.37

-6.14

RRPVPRRPS

4.20

-8.81

-6.58

RPVPRRPSQ

6.22

-8.14

-5.91
P40032

RLFPSILPN

5.09

-7.35

-5.12

ILPNVPHSD

6.00

-6.09

-3.86

LRLFPSILP

7.45

-5.40

-3.17
P32628

EPPIAPESA

9.19

-4.63

-2.40
Q12242

TKPCDVPNN

7.73

-6.00

-3.77

GTKPCDVPN

8.18

-4.48

-2.25
P38266

PPKPFRRSQ

3.43

-7.45

-5.22

PPPKPFRHT

4.59

-6.49

-4.26

SFPPPPLKP

4.73

-7.32

-5.09
P25333

KYPEGAPTS

8.64

-5.95

-3.72

TAITPAPTP

8.68

-4.44

-2.21

DKYPEGAPT

9.27

-3.86

-1.63
P16603

ELPDAPPVV

6.64

-6.52

-4.29

PNPELPDAP

8.11

-4.17

-1.94

RLPSNPSTP

8.44

-4.93

-2.70
P39692

KLPPSPKQP

4.43

-6.89

-4.66

LPPSPKQPV

6.69

-4.11

-1.88

PKQPVIMSG

6.98

-5.93

-3.70
P38872

LPNLYPHGT

7.69

-4.49

-2.26

INCLPNLYP

8.03

-5.76

-3.53
P17555

KSGPPPRPK

4.05

-6.95

-4.72

GPPPRPKKP

4.56

-7.88

-5.65

APPPPPPAP

5.82

-7.14

-4.91
Q12344

SPKLPPRGK

4.68

-7.31

-5.08

SPPLPPRQN

5.39

-7.41

-5.18

TTSSPPLPP

6.58

-4.21

-1.98
P38289

EDPENPSFI

7.93

-5.39

-3.16

DPENPSFIN

8.47

-5.43

-3.20

PENPSFINY

8.88

-7.46

-5.23
Q03780

APDIPPRSP

5.38

-5.91

-3.68

RPPPPPMDM

5.81

-8.63

-6.40

KRSRPPPPP

6.03

-5.52

-3.29
P53316

PPVPYIIPP

5.19

-6.66

-4.43

FGFIPQVPP

6.54

-5.19

-2.96

FIPQVPPVP

6.74

-5.88

-3.65
P32190

RRPSTAPAR

7.77

-6.74

-4.51

GLRRPSTAP

8.67

-3.63

-1.40
Q12389

LLEDPSQGP

8.03

-3.68

-1.45
P13186

DQQQAPLMP

5.65

-5.79

-3.56

QEPLPEREP

6.23

-8.45

-6.22

PPIPAALPP

6.25

-5.93

-3.70
P12630

SSNPFCLPN

7.42

-5.31

-3.08

DSSNPFCLP

8.35

-3.41

-1.18
P39940

TTWDDPRLP

3.45

-6.92

-4.69

TWDDPRLPS

7.07

-6.23

-4.00

PRLPSSLDQ

8.91

-6.11

-3.88
P04051

QDRSLPHFP

6.00

-4.57

-2.34

DRSLPHFPK

6.80

-4.85

-2.62

LPHFPKNSK

7.76

-4.15

-1.92
P43603

FTAPTSPST

8.54

-5.31

-3.08

GRFTAPTSP

9.50

-2.52

-0.29
P15891

PPPPPRRAT

3.35

-8.22

-5.99

APPPPPRRA

4.46

-7.61

-5.38

SKKEPVKTP

4.56

-5.20

-2.97
P07278

STPPLPMHF

6.42

-8.70

-6.47

KTSTPPLPM

9.04

-6.48

-4.25
P06777

PNEPDDIET

7.97

-5.21

-2.98
P27999

SDPTLPRSD

5.71

-5.60

-3.37

IGSDPTLPR

8.03

-7.03

-4.80
Q12532

PFKPYINGG

9.01

-4.86

-2.63
Q12168

PPPLPPRAN

5.13

-6.40

-4.17

IPPPVPNRP

5.99

-6.06

-3.83

NRGPPPLPP

5.99

-5.55

-3.32
Q04322

DQAPLDRPQ

4.30

-7.20

-4.97

SPPLPPRAD

4.84

-7.08

-4.85

TSPPLPPRA

6.67

-6.42

-4.19
P08458

TNLPKRKPP

4.22

-5.57

-3.34

MTNLPKRKP

4.76

-7.62

-5.39

NLPKRKPPK

6.04

-7.06

-4.83
Q02209

KGPESKPNV

6.12

-6.50

-4.27

YKGPESKPN

8.89

-4.58

-2.35
P47029

ESSILPRDP

5.29

-6.12

-3.89

DGHPASFPK

5.81

-6.34

-4.11

KGPKLPNLP

6.65

-5.23

-3.00
P32793

PTHPSNMSN

8.03

-6.12

-3.89
P36006

KSNKKPKNP

5.41

-5.78

-3.55

IPIPPPPPP

5.54

-6.20

-3.97

PPPPPPMGQ

6.05

-6.39

-4.16
P32875

PSKPDPMEP

5.20

-6.78

-4.55

TNRTPSKPD

7.91

-4.11

-1.88

SKPDPMEPE

7.95

-5.34

-3.11
Q08412

KKKWQPLPP

4.67

-6.24

-4.01

EDVPPQLPT

5.43

-6.57

-4.34

KWQPLPPEP

5.93

-5.92

-3.69
Q06440

KDRTPKVEP

6.99

-5.02

-2.79

RTPKVEPSK

8.18

-5.85

-3.62

DRTPKVEPS

9.32

-3.22

-0.99
Q12496

SNIPKKRPF

4.21

-8.00

-5.77

PSNIPKKRP

6.53

-5.37

-3.14

PEIPSNIPK

7.18

-5.73

-3.50
P26570

MEPKSPILK

5.63

-7.23

-5.00

EPKSPILKT

6.05

-6.27

-4.04

TPSKPNLEV

7.91

-4.18

-1.95
P31374

LDFEQPRLP

3.22

-6.60

-4.37

PERPSFRQP

4.19

-6.11

-3.88

TKPPPPLDF

5.42

-8.79

-6.56
P38237

DLNDPFVPP

6.40

-4.38

-2.15

VPPPNVPKK

6.53

-7.69

-5.46

LNDPFVPPP

6.61

-6.28

-4.05
P34223

PDNEPKQGD

7.45

-3.65

-1.42

EQPMPDNEP

7.85

-5.52

-3.29

SPAEVPKNE

8.24

-4.30

-2.07
P53118

VENPHDLPS

8.16

-5.78

-3.55
P32389

MQNNHPFEP

7.24

-4.08

-1.85

HPFEPNFMG

8.01

-3.76

-1.53

MGSPSQFPA

8.19

-4.95

-2.72
P53933

TRRRPPPPP

4.56

-6.26

-4.03

RRPPPPPIP

4.86

-7.40

-5.17

RTRRRPPPP

5.04

-6.92

-4.69
P32790

PPIKPPRPT

4.47

-4.62

-2.39

LPPIKPPRP

6.08

-6.91

-4.68

EGPPPAMPA

6.44

-7.82

-5.59
P33400

STSPQILPP

6.18

-5.74

-3.51

ILPPLPVGI

6.63

-6.57

-4.34

PQILPPLPV

6.98

-4.99

-2.76
P23293

SHPQFPISP

5.68

-6.77

-4.54

NKVPLPLGP

6.07

-6.00

-3.77

AIPRGPKKD

6.61

-6.30

-4.07
Q04439

IPPPPPPPP

4.83

-7.21

-4.98

PPPPPPPPP

5.39

-7.44

-5.21

HSKKPAPPP

5.48

-5.43

-3.20
P33338

PARTPARTP

6.18

-7.15

-4.92

LSWSGPLTP

6.83

-4.24

-2.01

PTPPVVAEP

7.89

-6.27

-4.04
Q12446

PPPPPRRGP

2.37

-8.11

-5.88

PPPPPMRTT

3.41

-8.75

-6.52

PPPPPHRHV

4.04

-7.88

-5.65
P22219

SPGETPYLI

9.04

-4.09

-1.86

PDFPYNNSN

9.48

-3.67

-1.44
P53220

RNKPKPLWP

3.96

-7.59

-5.36
Q12373

KRPLSQPTT

7.25

-6.08

-3.85

SKRPLSQPT

7.83

-3.25

-1.02

GSKRPLSQP

9.52

-4.90

-2.67
P41695

LAHETPVKP

6.41

-4.62

-2.39

TPVKPSLTS

8.31

-4.32

-2.09

ETPVKPSLT

9.46

-4.15

-1.92
Q00916

SRLFKPRPP

4.10

-6.38

-4.15

FKPRPPLSY

5.86

-7.91

-5.68

RLFKPRPPL

7.30

-7.08

-4.85
P53901

MRPIPPLPT

5.82

-7.31

-5.08

SNDPIILPP

6.01

-5.92

-3.69

LPPIPTRDD

6.32

-6.91

-4.68
P38990

TNQPSPIRP

3.97

-6.10

-3.87

NQPSPIRPV

4.48

-5.62

-3.39

RNQNLPKIP

6.17

-5.52

-3.29
P47110

STPPRKPSP

5.45

-7.02

-4.79

ATSTPPRKP

6.77

-5.38

-3.15

TPPRKPSPV

7.01

-5.32

-3.09
P10566

TRPIPAIPM

6.50

-7.83

-5.60

PAIPMDLPD

6.80

-5.17

-2.94

RPIPAIPMD

6.85

-5.19

-2.96
P25693

NRPIPTIKP

6.90

-6.99

-4.76
Q07821

DSQRPGKKP

5.41

-5.68

-3.45
P25558

ELPNTPRSI

4.37

-7.44

-5.21

HPKSPVKKP

4.92

-5.03

-2.80

RHPKSPVKK

6.11

-6.43

-4.20
P40325

QPRPPPRPQ

3.81

-7.62

-5.39

QPPRPPRPA

4.73

-7.56

-5.33

QSRPHQRPS

4.93

-7.48

-5.25
P38750

RSPPGVFPV

4.40

-6.95

-4.72

PGVFPVRGM

6.29

-7.67

-5.44

LPHNLPHNH

8.29

-5.30

-3.07
P37370

SQMPKPRPF

3.63

-9.27

-7.04

PHMPSVRPA

4.41

-7.48

-5.25

KSPPPPPSP

4.68

-7.36

-5.13
Q08446

NSSHSPISP

7.43

-4.03

-1.80
P47129

PNPPPNRSQ

5.44

-7.63

-5.40

TLPNRKPNP

6.00

-5.60

-3.37

NRKPNPPPN

6.52

-6.74

-4.51
P53169

TANSVPIMP

6.87

-3.62

-1.39

IMPTLPPRP

7.53

-5.12

-2.89

VPIMPTLPP

7.63

-5.58

-3.35

 


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