ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-25.PDB
Scoring matrix: RVS167_FYN-SSH-25_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 15.26
Foldx random average score for Saccharomyces cerevisiae: 16.311

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1748968
Proteins after disorder filtering: 4670
 Total fragments: 137483
Proteins after pattern filtering: 2314
 Total fragments: 21236
Proteins after MINT filtering: 73
 Total fragments: 1195


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

15.26

-1.31

0.00
Best peptides

RYPRKPYLN

0.00

-7.36

-6.05
         
Interactors      
P38140

PMNIQPDLP

6.20

-7.30

-5.99

NIPPHPYPS

8.63

-6.92

-5.61

IQPDLPPRK

9.43

-11.10

-9.79
Q06604

KNKPKPTPP

7.31

-7.98

-6.67

VKPAPPVSR

8.09

-7.28

-5.97

PKPTPPSPP

8.26

-7.81

-6.50
Q12365

IVPREPLRN

7.15

-9.20

-7.89

PREPLRNEP

9.74

-9.27

-7.96

QIPFIPPQE

10.79

-7.58

-6.27
P40072

PPTTKPGTN

9.53

-6.14

-4.83

TPSASPMLD

11.97

-4.04

-2.73

ANTPSASPM

12.17

-4.33

-3.02
P40956

NPKNVPFPF

8.46

-6.41

-5.10

STPPLPRRR

8.62

-10.83

-9.52

ATTSTPPLP

9.58

-7.31

-6.00
Q06833

NRRPVPRRP

6.76

-11.46

-10.15

RRPSQPLNT

7.02

-7.34

-6.03

PRRPSQPLN

7.41

-2.85

-1.54
P40032

ILPNVPHSD

8.72

-7.03

-5.72

LRLFPSILP

9.88

-4.96

-3.65

FPSILPNVP

11.88

-6.64

-5.33
P32628

EPPIAPESA

10.82

-6.10

-4.79

PPIAPESAT

13.05

-3.04

-1.73

PIAPESATT

14.59

-1.46

-0.15
Q12242

GTKPCDVPN

9.99

-2.83

-1.52

KPCDVPNNG

10.49

-5.49

-4.18

TKPCDVPNN

13.03

-5.44

-4.13
P38266

IYPIEPSLD

5.16

-9.15

-7.84

SFPPPPLKP

5.73

-10.29

-8.98

IRKRAPTPP

6.46

-8.16

-6.85
P25333

KYPEGAPTS

9.75

-6.74

-5.43

AITPAPTPT

11.11

-5.88

-4.57

TAITPAPTP

12.51

-4.49

-3.18
P16603

RLPSNPSTP

8.12

-8.15

-6.84

ELPDAPPVV

8.81

-7.15

-5.84

PNPELPDAP

9.54

-8.21

-6.90
P39692

VMKLPPSPK

7.96

-6.49

-5.18

KLPPSPKQP

9.06

-9.09

-7.78

PSPKQPVIM

10.39

-7.29

-5.98
P38872

GTLPLPNPY

9.84

-8.55

-7.24

LPNLYPHGT

12.01

-4.07

-2.76

INCLPNLYP

14.20

-2.75

-1.44
P17555

GPPPRPKKP

6.76

-9.82

-8.51

PRPKKPSTL

6.91

-9.97

-8.66

APPPPPPAP

8.16

-8.04

-6.73
Q12344

PTTSSPPLP

9.45

-5.85

-4.54

SPKLPPRGK

9.67

-5.36

-4.05

SPPLPPRQN

9.91

-7.52

-6.21
P38289

EDPENPSFI

10.76

-7.93

-6.62

VPTNDPSGI

12.43

-3.89

-2.58

DVPTNDPSG

13.33

-2.13

-0.82
Q03780

KRSRPPPPP

7.38

-6.84

-5.53

IKRSRPPPP

7.73

-8.91

-7.60

SRPPPPPMD

7.90

-9.02

-7.71
P53316

PYIIPPQNP

6.77

-9.42

-8.11

MMPMFPSFG

8.02

-7.83

-6.52

FIPQVPPVP

8.07

-8.08

-6.77
P32190

RRPSTAPAR

9.55

-6.74

-5.43

GLRRPSTAP

11.04

-5.69

-4.38

PSTAPARET

13.25

-3.51

-2.20
Q12389

DPSQGPAAN

11.70

-3.71

-2.40

LLEDPSQGP

13.00

-3.75

-2.44

LEDPSQGPA

13.94

-0.06

1.25
P13186

RPPIPAALP

8.21

-7.41

-6.10

LPEREPPTY

8.27

-5.82

-4.51

PLPEREPPT

9.01

-6.05

-4.74
P12630

NPFCLPNSN

11.06

-6.46

-5.15

PFCLPNSNT

12.02

-3.16

-1.85

SSNPFCLPN

12.15

-4.18

-2.87
P39940

TTWDDPRLP

8.81

-6.42

-5.11

DDPRLPSSL

9.64

-7.50

-6.19

TWDDPRLPS

11.63

-4.35

-3.04
P04051

SLPHFPKNS

8.28

-7.33

-6.02

QDRSLPHFP

10.76

-8.72

-7.41

PHFPKNSKT

12.41

-4.40

-3.09
P43603

GRFTAPTSP

10.60

-6.13

-4.82

TAPTSPSTS

12.41

-4.87

-3.56

FTAPTSPST

15.61

-2.74

-1.43
P15891

DEAAQPPLP

7.89

-5.78

-4.47

TPEKKPKEN

7.99

-6.16

-4.85

AQPPLPSRN

8.00

-10.70

-9.39
P07278

STPPLPMHF

9.12

-9.40

-8.09

KTSTPPLPM

11.43

-5.27

-3.96
P06777

LIPNEPDDI

10.09

-6.76

-5.45

PNEPDDIET

13.79

-1.70

-0.39

IPNEPDDIE

15.41

-1.30

0.01
P27999

DIGSDPTLP

11.17

-5.99

-4.68

SDPTLPRSD

12.02

-7.01

-5.70

DPTLPRSDR

12.54

-2.52

-1.21
P47029

ILPRDPPSY

6.38

-7.82

-6.51

KHPTPPSLK

7.35

-8.14

-6.83

KGPKLPNLP

8.37

-8.67

-7.36
Q12168

PPPLPPRAN

8.05

-7.31

-6.00

TNRGPPPLP

8.47

-7.76

-6.45

DDPYFPQFR

8.87

-7.51

-6.20
Q04322

SPPLPPRAD

10.13

-6.16

-4.85

TPPTLPPRR

10.26

-9.99

-8.68

TSPPLPPRA

10.74

-9.04

-7.73
P08458

LPKRKPPKL

6.76

-7.26

-5.95

PKRKPPKLQ

7.26

-8.00

-6.69

TNLPKRKPP

10.45

-4.69

-3.38
Q02209

IYKGPESKP

8.82

-5.47

-4.16

GPESKPNVN

9.73

-6.10

-4.79

YKGPESKPN

11.88

-4.20

-2.89
Q12496

IPSNIPKKR

9.78

-6.97

-5.66

NIPKKRPFL

9.94

-5.62

-4.31

SNIPKKRPF

12.88

-4.65

-3.34
P32793

HGPTHPSNM

9.42

-5.91

-4.60

SLGHGPTHP

13.41

-5.58

-4.27

PTHPSNMSN

15.26

-2.24

-0.93
P36006

PIPPPPPPM

7.34

-8.66

-7.35

ANIPIPPPP

7.72

-8.60

-7.29

NIPIPPPPP

8.01

-8.28

-6.97
P32875

RTPSKPDPM

7.10

-8.25

-6.94

PSKPDPMEP

9.36

-4.71

-3.40

KTNRTPSKP

9.54

-7.42

-6.11
Q08412

KKKWQPLPP

6.22

-7.43

-6.12

KWQPLPPEP

7.64

-8.22

-6.91

DEDVPPQLP

7.87

-7.03

-5.72
Q06440

RTPKVEPSK

10.42

-3.71

-2.40

DRTPKVEPS

13.64

-4.27

-2.96
P38750

TFPHNAPAS

11.07

-5.04

-3.73

LPHNLPHNH

11.81

-6.26

-4.95

LRSPPGVFP

12.38

-6.35

-5.04
P26570

STPSKPNLE

7.71

-7.73

-6.42

MEPKSPILK

9.04

-6.70

-5.39

SNVPDPSTP

10.02

-5.06

-3.75
P31374

FRKTKPPPP

5.93

-8.95

-7.64

TKPPPPLDF

7.05

-8.42

-7.11

KTKPPPPLD

7.37

-7.29

-5.98
P38237

NDPFVPPPN

7.69

-7.82

-6.51

PFVPPPNVP

7.95

-7.91

-6.60

QIPSKPENT

9.03

-7.50

-6.19
P34223

PMPDNEPKQ

9.61

-5.08

-3.77

EQPMPDNEP

10.51

-5.61

-4.30

SPAEVPKNE

10.60

-5.10

-3.79
P53118

PHDLPSHLG

12.01

-4.40

-3.09

VENPHDLPS

13.88

-0.88

0.43

NPHDLPSHL

14.13

-8.17

-6.86
P32389

NHPFEPNFM

7.31

-8.47

-7.16

MQNNHPFEP

9.79

-5.20

-3.89

NNHPFEPNF

12.20

-1.80

-0.49
P53933

KRVAPPPLP

5.08

-10.45

-9.14

TRRRPPPPP

5.88

-8.19

-6.88

RRPPPPPIP

6.50

-9.34

-8.03
P32790

IKPPRPTST

7.87

-7.41

-6.10

LPPIKPPRP

7.92

-9.94

-8.63

PPPAMPARP

8.99

-9.41

-8.10
P33400

SYVQPPNAP

7.72

-7.71

-6.40

SPQILPPLP

8.04

-8.51

-7.20

ILPPLPVGI

8.56

-9.21

-7.90
P23293

SRPSHPQFP

7.07

-8.42

-7.11

NKVPLPLGP

8.57

-8.30

-6.99

SHPQFPISP

8.83

-6.25

-4.94
Q04439

SKKPAPPPP

6.95

-7.87

-6.56

NIPPPPPPP

7.58

-8.83

-7.52

IPPPPPPPP

7.76

-8.88

-7.57
P33338

ARTPTPTPP

8.48

-7.79

-6.48

ARTPARTPT

11.13

-3.06

-1.75

TPTPTPPVV

11.43

-6.37

-5.06
Q12446

NRPVPPPPP

6.18

-8.53

-7.22

RLPAPPPPP

6.24

-8.67

-7.36

SAPIPPTLP

7.22

-7.94

-6.63
P22219

SPGETPYLI

11.57

-5.47

-4.16

AVSPGETPY

12.92

-3.29

-1.98

PDFPYNNSN

14.17

-2.47

-1.16
P53220

RNKPKPLWP

7.45

-9.71

-8.40
Q12373

KRPLSQPTT

10.78

-1.12

0.19

RPLSQPTTS

11.77

-4.38

-3.07

SKRPLSQPT

12.37

-5.86

-4.55
P41695

ETPVKPSLT

6.85

-8.25

-6.94

LAHETPVKP

12.83

-6.32

-5.01

TPVKPSLTS

15.36

-2.33

-1.02
Q00916

LFKPRPPLS

4.81

-9.38

-8.07

SRLFKPRPP

6.22

-9.06

-7.75

FKPRPPLSY

6.55

-8.77

-7.46
P53901

AMRPIPPLP

4.03

-10.67

-9.36

MRPIPPLPT

7.55

-7.73

-6.42

NSPKLPPLP

7.62

-8.60

-7.29
P38990

PSPIRPVLP

6.71

-8.16

-6.85

SVPNLPSAP

8.82

-8.48

-7.17

SVSSVPNLP

9.38

-6.92

-5.61
P47110

TPPRKPSPV

7.32

-7.16

-5.85

SKPNSPKET

8.92

-6.51

-5.20

ATSTPPRKP

11.39

-7.16

-5.85
P10566

TRPIPAIPM

8.06

-7.06

-5.75

PIPAIPMDL

9.25

-7.50

-6.19

STRPIPAIP

9.27

-7.79

-6.48
P25693

NRPIPTIKP

15.80

-6.21

-4.90
Q07821

DSQRPGKKP

13.02

-5.04

-3.73
P25558

RHPKSPVKK

9.08

-7.73

-6.42

ELPNTPRSI

9.63

-7.38

-6.07

SPVKKPMTS

10.67

-5.60

-4.29
P40325

PRPPRPAAN

4.97

-9.32

-8.01

SQPPRPPRP

7.28

-11.38

-10.07

SQPRPPPRP

7.69

-10.03

-8.72
P37370

SQMPKPRPF

5.98

-9.02

-7.71

NRPHMPSVR

6.39

-8.65

-7.34

PAPPPPPLP

6.41

-8.82

-7.51
Q08446

SHSPISPLK

10.72

-5.52

-4.21

NSSHSPISP

14.14

-3.00

-1.69
P39743

NATIPEDNP

11.83

-2.26

-0.95

SNPLTSPVA

14.79

-3.63

-2.32
P47129

NRKPNPPPN

5.60

-6.92

-5.61

RKPNPPPNR

6.29

-7.28

-5.97

LPNRKPNPP

8.29

-6.69

-5.38
P53169

SVPIMPTLP

5.21

-9.12

-7.81

IMPTLPPRP

8.80

-11.90

-10.59

MPTLPPRPY

9.30

-6.38

-5.07

 


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