ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-23.PDB
Scoring matrix: RVS167_FYN-SSH-23_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 12.05
Foldx random average score for Saccharomyces cerevisiae: 11.204

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1804243
Proteins after disorder filtering: 4790
 Total fragments: 108020
Proteins after pattern filtering: 2104
 Total fragments: 8021
Proteins after MINT filtering: 69
 Total fragments: 411


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

12.05

-0.56

0.00
Best peptides

YPMMPYY

0.00

-4.83

-4.27
         
Interactors      
P38140

IPPHPYP

6.05

-1.94

-1.38

QPDLPPR

6.73

-1.96

-1.40

IQPDLPP

10.70

-0.75

-0.19
Q06604

GPRMPSR

5.32

-5.33

-4.77

LPTRPNK

6.06

-4.65

-4.09

KPLLPTR

6.58

-3.78

-3.22
Q12365

VPREPLR

5.74

-3.75

-3.19

IVPREPL

6.84

-4.74

-4.18

IPGKFPS

8.94

-1.95

-1.39
P40072

TPSASPM

8.14

-2.42

-1.86

PTTKPGT

9.99

-1.36

-0.80

PSASPML

10.13

-1.78

-1.22
P40956

TPPLPRR

5.46

-1.16

-0.60

NPKNVPF

8.07

-2.38

-1.82

WNPKNVP

10.86

-6.43

-5.87
Q06833

VPRRPSQ

5.85

-4.48

-3.92

RPSQPLN

6.77

-3.29

-2.73

RRPSQPL

8.12

-4.05

-3.49
P40032

PSILPNV

7.73

-0.09

0.47

NVPHSDP

9.13

0.56

1.12

LFPSILP

9.20

-3.96

-3.40
P32628

PPIAPES

9.80

-2.08

-1.52
Q12242

TKPCDVP

9.26

-2.52

-1.96
P38266

YPIEPSL

4.20

-4.64

-4.08

VPILPPR

4.89

-4.47

-3.91

PPLKPGQ

6.73

-4.16

-3.60
P25333

YPEGAPT

9.00

-2.98

-2.42

ITPAPTP

9.94

-3.02

-2.46

KYPEGAP

10.94

-2.65

-2.09
P16603

LPDAPPV

7.65

-4.05

-3.49

LPSNPST

8.64

-1.83

-1.27

NPELPDA

8.83

0.13

0.69
P39692

SPKQPVI

8.09

-2.91

-2.35

LPPSPKQ

8.49

-3.42

-2.86

PSPKQPV

9.36

-1.37

-0.81
P38872

LPNLYPH

6.70

-1.80

-1.24

TLPLPNP

7.85

-0.84

-0.28

CLPNLYP

9.12

-1.58

-1.02
P17555

RPKKPST

5.57

-5.99

-5.43

PPPRPKK

6.86

-2.98

-2.42

PRPKKPS

9.05

-2.80

-2.24
Q12344

SPKLPPR

5.80

-2.24

-1.68

SPPLPPR

6.60

-0.89

-0.33

TSPKLPP

7.99

-2.89

-2.33
Q03780

IPPRSPN

7.77

-2.88

-2.32

PPRSPNR

8.63

-3.41

-2.85

RSRPPPP

11.20

-5.62

-5.06
P53316

IPPQNPA

8.99

-2.16

-1.60

FIPQVPP

9.69

-5.16

-4.60

MMPMFPS

10.06

-4.22

-3.66
P32190

RRPSTAP

8.92

-4.77

-4.21

PSTAPAR

10.41

-2.71

-2.15
Q12389

DPSQGPA

9.89

-0.81

-0.25
P13186

LPEREPP

6.50

-3.40

-2.84

IPMSPNY

6.60

-4.76

-4.20

NIPLTPL

7.46

-1.69

-1.13
P12630

NPFCLPN

9.12

-1.86

-1.30

PFCLPNS

9.62

-3.09

-2.53
P39940

DPRLPSS

7.09

-1.25

-0.69

DDPRLPS

9.55

-1.59

-1.03

PSSSPHS

10.66

-0.33

0.23
P04051

PAMLPGS

7.33

-2.35

-1.79

SLPHFPK

8.12

-0.08

0.48

NPAMLPG

8.72

-2.93

-2.37
P40325

RPPRPAA

6.65

-5.11

-4.55

RPHQRPS

6.85

-3.64

-3.08

NPSLPWT

6.92

0.10

0.66
P15891

TPEKKPK

7.20

-2.28

-1.72

QPPLPSR

7.80

-3.59

-3.03

PEKKPKE

8.01

-3.04

-2.48
P07278

TPPLPMH

6.41

-1.09

-0.53
P06777

IPNEPDD

9.47

-0.76

-0.20

LIPNEPD

9.67

-1.78

-1.22
P27999

DPTLPRS

8.11

0.32

0.88
P47029

GPKLPNL

6.66

-1.76

-1.20

LSPLGAP

6.85

-4.06

-3.50

LPNLPND

7.42

-2.57

-2.01
Q12168

PPPLPPR

6.78

-0.92

-0.36

PVPKPNI

8.69

-3.26

-2.70

VPNRPGG

9.11

-2.00

-1.44
Q04322

SPPLPPR

6.60

-0.89

-0.33

PPTLPPR

7.21

-2.49

-1.93

PLDRPQL

7.44

-6.14

-5.58
P08458

LPKRKPP

5.13

-5.90

-5.34

PKRKPPK

5.61

-4.71

-4.15

NLPKRKP

7.80

-3.19

-2.63
Q02209

PESKPNV

8.98

-1.35

-0.79

KGPESKP

10.30

-3.05

-2.49
Q12496

IPKKRPF

4.96

-4.37

-3.81

PKKRPFL

6.13

-5.40

-4.84

NIPKKRP

7.30

-2.69

-2.13
P32793

GPTHPSN

9.70

-0.01

0.55
P36006

PPPMGQP

8.14

-3.45

-2.89

GQPKDPK

8.26

-2.52

-1.96

PPMGQPK

8.56

-4.38

-3.82
P32875

TPSKPDP

7.44

-1.91

-1.35

PDPMEPE

8.49

-2.36

-1.80

RTPSKPD

9.63

-3.38

-2.82
Q08412

LPTQPVR

7.35

-4.35

-3.79

LPPEPLD

7.74

-2.65

-2.09

PPQLPTR

7.96

-2.60

-2.04
Q06440

RTPKVEP

6.70

-5.26

-4.70

PKVEPSK

8.72

-1.96

-1.40
P38750

PPILPRT

6.04

-0.87

-0.31

LPHNLPH

8.18

-2.01

-1.45

PHNLPHN

8.18

-1.93

-1.37
P26570

TPSKPNL

7.04

-1.78

-1.22

EPKSPIL

8.57

-2.87

-2.31

STPLNSP

8.74

-1.73

-1.17
P31374

PDDLPPL

6.54

-0.97

-0.41

QPRLPST

7.30

-4.82

-4.26

SPERPSF

7.50

-2.22

-1.66
P38237

IPSKPEN

7.42

-1.91

-1.35

PPPNVPK

9.55

-1.17

-0.61
P34223

SPAEVPK

8.66

-1.19

-0.63

MPDNEPK

9.62

-4.03

-3.47

PDNEPKQ

9.65

-1.92

-1.36
P53118

PHDLPSH

7.50

-1.16

-0.60

ENPHDLP

8.96

-0.20

0.36
P32389

HPFEPNF

8.65

-1.40

-0.84

SPSQFPA

9.45

-0.93

-0.37

GSPSQFP

10.76

-2.21

-1.65
P53933

LPMELPH

5.52

-4.97

-4.41

PPPLPNR

7.33

-1.55

-0.99

DLPMELP

7.93

-3.14

-2.58
P32790

PPIKPPR

6.11

-2.90

-2.34

PAPLDPF

7.31

-1.24

-0.68

APLDPFK

7.58

-2.93

-2.37
P33400

PQILPPL

6.37

-0.82

-0.26

LPPLPVG

7.32

-3.28

-2.72

TSPQILP

8.88

-2.62

-2.06
P23293

RPSHPQF

4.83

-2.20

-1.64

IPRGPKK

6.95

-4.15

-3.59

AIPRGPK

7.88

-2.90

-2.34
Q04439

SKPKEPM

6.91

-2.70

-2.14

KPKEPMF

7.11

-6.02

-5.46

SPSELPL

8.08

-0.96

-0.40
P33338

SGPLTPP

8.16

-0.29

0.27

RTPARTP

8.75

-5.12

-4.56

TPARTPT

8.75

-2.20

-1.64
Q12446

LPQLPNR

5.84

-2.39

-1.83

LPPLPNQ

6.19

-1.06

-0.50

PPRRGPA

7.51

-4.74

-4.18
P22219

SPGETPY

8.63

-1.97

-1.41

NPDFPYN

11.15

-0.99

-0.43
Q12373

RPLSQPT

7.31

-5.11

-4.55

KRPLSQP

9.01

-1.79

-1.23

PLSQPTT

10.25

-1.64

-1.08
P41695

TPVKPSL

7.37

-2.55

-1.99
Q00916

FKPRPPL

7.55

-5.12

-4.56

RPTDYPY

8.21

-3.55

-2.99
P53901

SPKLPPL

5.90

-1.92

-1.36

LPPLPTT

6.82

-1.21

-0.65

PIILPPT

7.38

-1.42

-0.86
P38990

SPIRPVL

6.66

-2.61

-2.05

VPNLPSA

8.29

-2.80

-2.24

LPSAPSS

8.80

-3.60

-3.04
P47110

PPRKPSP

6.47

-3.60

-3.04

TPPRKPS

8.27

-2.82

-2.26

SKPNSPK

9.58

-1.14

-0.58
P10566

PMDLPDY

6.31

-1.70

-1.14

AIPMDLP

8.00

-3.94

-3.38

IPMDLPD

9.12

-2.07

-1.51
P25558

RHPKSPV

6.69

-4.18

-3.62

SPVKKPM

6.96

-2.60

-2.04

PVKKPMT

7.60

-3.47

-2.91
P38289

DPENPSF

9.97

-0.39

0.17

EDPENPS

10.42

-0.62

-0.06

VPTNDPS

11.12

-0.69

-0.13
P37370

RPHMPSV

5.26

-4.86

-4.30

LAPLPPP

5.84

-2.70

-2.14

IPLAPLP

6.76

-5.78

-5.22
Q08446

SPISPLK

8.24

-1.70

-1.14
P39743

SNPLTSP

8.60

-0.81

-0.25

TIPEDNP

9.76

-1.54

-0.98
P47129

PPLLPPR

5.00

-3.65

-3.09

LPNRKPN

7.24

-3.90

-3.34

PNRKPNP

7.35

-3.27

-2.71
P53169

VPIMPTL

5.62

-4.38

-3.82

MPTLPPR

8.26

-2.86

-2.30

YSPAQPS

8.44

-4.33

-3.77

 


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