ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-19.PDB
Scoring matrix: RVS167_FYN-SSH-19_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 12.81
Foldx random average score for Saccharomyces cerevisiae: 11.931

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1534885
Proteins after disorder filtering: 4537
 Total fragments: 73933
Proteins after pattern filtering: 2165
 Total fragments: 10333
Proteins after MINT filtering: 69
 Total fragments: 540


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

12.81

-1.05

0.00
Best peptides

RIFMRGLLF

0.00

-6.50

-5.45
         
Interactors      
P38140

PDLPPRKIM

7.30

-8.79

-7.74

NIQPDLPPR

8.55

-6.13

-5.08

ANIPPHPYP

10.32

-7.94

-6.89
Q06604

GPRMPSRGR

5.65

-4.88

-3.83

PPSPPAKRI

6.71

-6.36

-5.31

PPLPTRRDH

7.76

-4.72

-3.67
Q12365

VPREPLRNE

9.37

-2.03

-0.98

VKDIPGKFP

9.78

-4.83

-3.78

DIPGKFPSP

10.97

-5.81

-4.76
P40072

DAAPPTTKP

9.84

-7.69

-6.64

PTTKPGTNS

10.17

-5.82

-4.77

APPTTKPGT

10.82

-1.81

-0.76
P40956

PPLPRRRAT

7.45

-6.35

-5.30

TSTPPLPRR

8.61

-6.67

-5.62

FWNPKNVPF

8.91

-5.71

-4.66
Q06833

RPVPRRPSQ

5.89

-5.26

-4.21

VPRRPSQPL

8.73

-2.80

-1.75

FPVPPSASN

8.87

-4.13

-3.08
P40032

LRLFPSILP

10.18

-8.55

-7.50

LPNVPHSDP

10.52

-4.60

-3.55

LFPSILPNV

11.25

-3.12

-2.07
P32628

PPIAPESAT

11.11

-2.79

-1.74

PIAPESATT

11.22

-4.89

-3.84
P22219

AVSPGETPY

10.77

-4.33

-3.28

PGETPYLIT

11.08

-6.20

-5.15

SAVSPGETP

11.09

-5.84

-4.79
P38266

PPLKPGQKT

6.47

-5.35

-4.30

PPKPFRHGL

6.63

-5.76

-4.71

NIYPIEPSL

7.16

-6.02

-4.97
P25333

DKYPEGAPT

9.36

-3.38

-2.33
P16603

NPSTPVIMI

10.34

-5.51

-4.46

FPNPELPDA

10.83

-2.13

-1.08

FRLPSNPST

11.19

-4.56

-3.51
P39692

PPSPKQPVI

7.57

-5.67

-4.62

MKLPPSPKQ

7.83

-7.13

-6.08

LPPSPKQPV

10.84

-2.61

-1.56
P38872

NCLPNLYPH

10.20

-3.89

-2.84
P17555

RPKKPSTLK

4.95

-6.84

-5.79

PPAPPASVF

7.31

-6.35

-5.30

SGPPPRPKK

8.29

-7.02

-5.97
Q12344

PPLPPRQNV

7.72

-5.66

-4.61

PKLPPRGKQ

7.86

-9.26

-8.21

TSSPPLPPR

10.33

-6.30

-5.25
P38289

DPENPSFIN

9.03

-4.07

-3.02

PENPSFINY

11.03

-4.79

-3.74
Q03780

DIPPRSPNR

5.86

-8.46

-7.41

PPPPMDMKS

8.59

-5.15

-4.10

PPPPPMDMK

8.77

-9.19

-8.14
P53316

WMMPMFPSF

8.18

-7.27

-6.22

MPMFPSFGF

8.35

-3.66

-2.61

VPPVPYIIP

10.07

-5.54

-4.49
P32190

RRPSTAPAR

9.59

-4.48

-3.43

GLRRPSTAP

11.58

-6.54

-5.49
Q12389

EDPSQGPAA

11.24

-1.56

-0.51

LLEDPSQGP

11.41

-3.19

-2.14
P13186

RPPIPAALP

8.46

-5.32

-4.27

NNIPLTPLA

9.28

-6.28

-5.23

EPLPEREPP

9.46

-4.31

-3.26
P12630

DSSNPFCLP

10.67

-7.06

-6.01
P39940

PRLPSSLDQ

9.59

-5.11

-4.06

WDDPRLPSS

11.04

-5.08

-4.03

PSSSPHSQA

11.76

-4.06

-3.01
P04051

RSLPHFPKN

8.10

-6.66

-5.61

PHFPKNSKT

10.50

-5.27

-4.22

VNPAMLPGS

11.79

-2.18

-1.13
P43603

APTSPSTSS

10.57

-1.78

-0.73
P15891

RRATPEKKP

8.51

-7.98

-6.93

PPPPPRRAT

8.81

-6.31

-5.26

PPPPRRATP

8.89

-9.40

-8.35
P07278

TSTPPLPMH

10.21

-7.73

-6.68
P06777

IPNEPDDIE

11.38

-2.15

-1.10
P27999

PTLPRSDRE

10.66

-7.54

-6.49

IGSDPTLPR

11.49

-3.39

-2.34
P47029

HPTPPSLKA

5.81

-4.36

-3.31

PITSPMSNM

8.53

-6.05

-5.00

PRDPPSYKD

9.16

-7.49

-6.44
Q12168

PPLPPRANV

7.82

-5.12

-4.07

NDDPYFPQF

8.41

-6.76

-5.71

VPNRPGGTT

8.41

-2.44

-1.39
P08458

NLPKRKPPK

9.13

-7.23

-6.18

TNLPKRKPP

9.44

-7.29

-6.24

PITNPSSSS

11.29

-4.44

-3.39
Q02209

PESKPNVNF

9.24

-4.93

-3.88

YKGPESKPN

11.86

-3.42

-2.37
Q12496

NIPKKRPFL

7.41

-9.41

-8.36

SNIPKKRPF

7.99

-7.39

-6.34

EIPSNIPKK

10.68

-5.29

-4.24
P36006

MGQPKDPKF

6.73

-6.92

-5.87

KPKNPGGLS

6.79

-4.46

-3.41

PPPPMGQPK

6.93

-5.88

-4.83
P32875

TPSKPDPME

9.62

-4.31

-3.26

NRTPSKPDP

10.48

-5.72

-4.67
Q08412

DVPPQLPTR

8.19

-6.67

-5.62

QPLPPEPLD

8.21

-5.77

-4.72

PQLPTRTKS

9.10

-5.17

-4.12
Q06440

RTPKVEPSK

10.60

-4.10

-3.05

DRTPKVEPS

10.76

-5.22

-4.17

KDRTPKVEP

11.61

-6.08

-5.03
P38750

LRSPPGVFP

7.90

-8.27

-7.22

LGLPHNLPH

8.75

-5.62

-4.57

PILPRTTQD

8.77

-7.89

-6.84
P26570

PLNSPGLSK

7.87

-4.39

-3.34

TPSKPNLEV

9.46

-1.44

-0.39

DPSTPSKPN

9.73

-2.51

-1.46
P31374

NISPERPSF

7.23

-6.06

-5.01

SPERPSFRQ

8.30

-3.34

-2.29

KPPPPLDFE

9.34

-6.55

-5.50
P38237

FVPPPNVPK

9.21

-5.89

-4.84

VPPPNVPKK

9.51

-4.89

-3.84

NFQIPSKPE

11.04

-2.68

-1.63
P34223

QPMPDNEPK

9.85

-3.54

-2.49

ESSPAEVPK

11.42

-3.39

-2.34

PMPDNEPKQ

11.45

-4.69

-3.64
P53118

VENPHDLPS

10.56

-2.84

-1.79

SVENPHDLP

10.62

-7.51

-6.46
P32389

NNHPFEPNF

9.05

-4.35

-3.30

HPFEPNFMG

10.46

-4.85

-3.80

PFEPNFMGS

10.57

-3.27

-2.22
P53933

PPLPNRQLP

7.31

-7.49

-6.44

NDLPMELPH

8.89

-5.02

-3.97

PPPIPSTQK

9.20

-4.70

-3.65
P32790

APAPLDPFK

8.72

-6.09

-5.04

PIKPPRPTS

9.20

-6.96

-5.91

PPAMPARPT

9.24

-4.04

-2.99
P33400

HSTSPQILP

9.37

-6.14

-5.09

QILPPLPVG

9.69

-6.40

-5.35

VQPPNAPSY

10.61

-4.46

-3.41
P23293

GAIPRGPKK

6.26

-7.29

-6.24

VPLPLGPQS

7.27

-2.39

-1.34

FPISPSQGQ

8.18

-2.42

-1.37
Q04439

APPPPGMQN

6.55

-4.19

-3.14

PPPPPSSKP

8.54

-8.96

-7.91

SSKPKEPMF

8.94

-7.90

-6.85
P33338

ARTPARTPT

10.46

-4.64

-3.59

TPTPPVVAE

11.08

-2.62

-1.57
Q12446

RPLPQLPNR

5.84

-4.30

-3.25

PPPPPRRGP

7.20

-7.55

-6.50

PPPPPHRHV

7.27

-7.88

-6.83
Q04322

DQAPLDRPQ

9.16

-4.55

-3.50

NDQAPLDRP

11.56

-6.68

-5.63

SSTPPTLPP

11.67

-6.77

-5.72
Q12373

GSKRPLSQP

11.12

-6.93

-5.88

SKRPLSQPT

11.83

-3.65

-2.60
P41695

HETPVKPSL

9.11

-3.83

-2.78

TPVKPSLTS

9.50

-2.83

-1.78

PVKPSLTSN

10.86

-4.53

-3.48
Q00916

KPRPPLSYK

6.89

-5.10

-4.05

PRPPLSYKR

7.41

-7.59

-6.54

RLFKPRPPL

8.21

-6.72

-5.67
P53901

RPIPPLPTE

7.98

-4.68

-3.63

PPIPTRDDM

8.83

-4.78

-3.73

PPLPTESEY

9.36

-4.45

-3.40
P38990

QPSPIRPVL

7.17

-3.99

-2.94

LPSAPSSTR

9.22

-2.93

-1.88

EIPSPAKNP

9.43

-5.94

-4.89
P47110

KPNSPKETD

10.14

-2.37

-1.32

TSTPPRKPS

10.78

-4.71

-3.66

GSKPNSPKE

10.82

-4.39

-3.34
P10566

AIPMDLPDY

9.81

-5.10

-4.05

IPAIPMDLP

10.14

-4.03

-2.98

PAIPMDLPD

11.11

-4.81

-3.76
P25693

NRPIPTIKP

10.23

-7.75

-6.70
Q07821

DSQRPGKKP

6.80

-7.02

-5.97
P25558

HPKSPVKKP

9.03

-4.15

-3.10

LPNTPRSIN

9.07

-5.17

-4.12

PNTPRSINV

9.15

-6.19

-5.14
P40325

RPPRPAANL

7.64

-4.28

-3.23

PRPPPRPQQ

8.25

-7.94

-6.89

HQSRPHQRP

8.40

-7.98

-6.93
P37370

RPSPISPSI

6.86

-2.69

-1.64

AVTPGGPLP

7.50

-6.98

-5.93

RPHMPSVRP

7.55

-6.70

-5.65
Q08446

SHSPISPLK

9.45

-6.16

-5.11
P47129

PLLPPRNTM

10.06

-7.89

-6.84

PNPPPNRSQ

10.10

-5.59

-4.54

NTLPNRKPN

10.62

-4.98

-3.93
P53169

PIMPTLPPR

8.42

-6.53

-5.48

VPIMPTLPP

8.68

-4.37

-3.32

NSVPIMPTL

9.62

-4.96

-3.91

 


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