ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-18.PDB
Scoring matrix: RVS167_FYN-SSH-18_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 19.29
Foldx random average score for Saccharomyces cerevisiae: 16.167

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1373306
Proteins after disorder filtering: 4397
 Total fragments: 68099
Proteins after pattern filtering: 2162
 Total fragments: 12281
Proteins after MINT filtering: 71
 Total fragments: 660


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

19.29

-2.49

0.00
Best peptides

RPPIRPIWFW

0.00

1.59

4.08
         
Interactors      
P38140

IQPDLPPRKI

11.93

-3.54

-1.05

PMNIQPDLPP

13.71

-4.59

-2.10

QPDLPPRKIM

13.79

-6.38

-3.89
Q06604

LLPTRPNKAE

8.74

-5.78

-3.29

TPPSPPAKRI

12.36

-5.82

-3.33

YSNIPSSKPA

12.38

-5.94

-3.45
Q12365

IPFIPPQEDD

11.28

-6.82

-4.33

VKDIPGKFPS

12.14

-6.01

-3.52

IVPREPLRNE

14.08

-4.61

-2.12
P40072

PPTTKPGTNS

13.32

-6.18

-3.69

TPSASPMLDA

14.38

-5.01

-2.52

APPTTKPGTN

15.24

-3.81

-1.32
P40956

RFWNPKNVPF

10.70

-2.45

0.04

NPKNVPFPFD

12.16

-5.93

-3.44

WNPKNVPFPF

12.90

-5.31

-2.82
Q06833

PVPRRPSQPL

12.35

-4.20

-1.71

RPVPRRPSQP

12.83

-5.86

-3.37

FPVPPSASNM

13.02

-5.57

-3.08
P40032

FPSILPNVPH

7.54

-8.10

-5.61

LRLFPSILPN

12.72

-3.82

-1.33

LPNVPHSDPS

14.01

-7.39

-4.90
P32628

EPPIAPESAT

11.07

-6.96

-4.47
Q12242

KPCDVPNNGD

14.23

-4.59

-2.10
P38266

AVPILPPRNN

11.07

-5.96

-3.47

LKKKPPVVPK

11.29

-5.82

-3.33

LPPPKPFRHT

11.42

-7.07

-4.58
P25333

YPEGAPTSGA

15.99

-4.41

-1.92
P16603

RLPSNPSTPV

12.39

-5.35

-2.86

LPSNPSTPVI

13.58

-5.34

-2.85

SNPSTPVIMI

13.83

-2.96

-0.47
P39692

PSPKQPVIMS

13.83

-4.89

-2.40

KLPPSPKQPV

14.21

-4.69

-2.20

SPKQPVIMSG

14.31

-5.58

-3.09
P38872

LPNLYPHGTL

13.10

-5.03

-2.54

SINCLPNLYP

14.37

-3.67

-1.18

CLPNLYPHGT

14.75

-3.21

-0.72
P17555

RPKKPSTLKT

9.38

-7.78

-5.29

GPPPRPKKPS

12.45

-6.08

-3.59

KSGPPPRPKK

15.30

-4.36

-1.87
Q12344

SPKLPPRGKQ

13.33

-6.75

-4.26

SPPLPPRQNV

13.76

-7.27

-4.78

PLPPRQNVAT

14.59

-3.90

-1.41
P38289

DPENPSFINY

12.20

-5.51

-3.02

VPTNDPSGIL

13.67

-4.61

-2.12

MYDVPTNDPS

15.70

-4.04

-1.55
Q03780

RPPPPPMDMK

10.02

-7.32

-4.83

APDIPPRSPN

10.35

-7.87

-5.38

IPPRSPNRNA

11.45

-6.63

-4.14
P53316

MMPMFPSFGF

11.25

-4.94

-2.45

MPMFPSFGFI

11.33

-7.09

-4.60

IPQVPPVPYI

11.54

-7.56

-5.07
P32190

RPSTAPARET

10.34

-5.28

-2.79

RRPSTAPARE

14.94

-2.99

-0.50

GLRRPSTAPA

15.85

-3.37

-0.88
Q12389

LLEDPSQGPA

13.92

-5.34

-2.85

DPSQGPAANG

14.91

-4.66

-2.17
P13186

RPPIPAALPP

11.27

-7.51

-5.02

RNSSIPMSPN

13.06

-4.27

-1.78

SIPMSPNYGN

14.05

-4.46

-1.97
P12630

NPFCLPNSNT

12.82

-5.71

-3.22
P39940

WDDPRLPSSL

14.43

-2.05

0.44

DPRLPSSLDQ

15.55

-6.06

-3.57

TTWDDPRLPS

16.05

-4.05

-1.56
P04051

LPHFPKNSKT

12.76

-6.91

-4.42

QDRSLPHFPK

13.20

-3.51

-1.02

FQDRSLPHFP

13.62

-5.55

-3.06
P43603

TAPTSPSTSS

15.54

-3.26

-0.77

GRFTAPTSPS

15.76

-2.92

-0.43
P15891

RRATPEKKPK

12.94

-4.31

-1.82

APPPPPRRAT

13.38

-6.06

-3.57

KPEVPEDEPE

14.56

-7.18

-4.69
P07278

KTSTPPLPMH

14.68

-3.60

-1.11
P06777

LIPNEPDDIE

14.39

-1.90

0.59
P27999

SDPTLPRSDR

14.50

-2.28

0.21

DIGSDPTLPR

15.31

-2.91

-0.42
P47029

KHPTPPSLKA

10.42

-2.57

-0.08

LPRDPPSYKD

10.44

-7.15

-4.66

ILPRDPPSYK

11.51

-5.07

-2.58
Q12168

PVPNRPGGTT

12.36

-1.65

0.84

DDPYFPQFRS

13.78

-2.23

0.26

IPPPVPNRPG

13.88

-6.40

-3.91
Q04322

TPPTLPPRRI

10.71

-6.75

-4.26

TPSKSPTSAV

13.69

-6.02

-3.53

KNDQAPLDRP

15.43

-2.54

-0.05
P08458

NLPKRKPPKL

12.20

-5.95

-3.46

PKRKPPKLQG

12.70

-5.43

-2.94

VMTNLPKRKP

12.97

-3.24

-0.75
Q02209

GPESKPNVNF

12.87

-4.56

-2.07

PESKPNVNFM

13.72

-3.46

-0.97
Q12496

IPSNIPKKRP

12.58

-4.85

-2.36

PSNIPKKRPF

13.76

-5.99

-3.50

EIPSNIPKKR

15.40

-3.15

-0.66
P32793

HGPTHPSNMS

13.85

-4.33

-1.84

GPTHPSNMSN

13.92

-5.41

-2.92

SLGHGPTHPS

14.94

-3.90

-1.41
P36006

KPKNPGGLSG

12.28

-5.67

-3.18

GQPKDPKFEA

13.61

-2.14

0.35

IPPPPPPMGQ

14.18

-5.39

-2.90
P32875

VKTNRTPSKP

13.92

-4.69

-2.20

RTPSKPDPME

15.01

-3.46

-0.97

TPSKPDPMEP

15.30

-5.90

-3.41
Q08412

ELPTQPVRKN

11.16

-4.67

-2.18

VPPQLPTRTK

12.58

-4.38

-1.89

GKNSRPQQPE

14.00

-4.71

-2.22
Q06440

KDRTPKVEPS

14.27

-3.90

-1.41

KKDRTPKVEP

15.33

-3.41

-0.92
P38750

PPGVFPVRGM

12.67

-4.82

-2.33

FPHNAPASSP

13.31

-5.03

-2.54

APASSPAYTD

14.62

-3.34

-0.85
P26570

MEPKSPILKT

9.62

-4.11

-1.62

TPLNSPGLSK

12.15

-4.92

-2.43

DPTDSPNEWE

12.67

-6.12

-3.63
P31374

TPDDLPPLKE

11.75

-6.24

-3.75

ISPERPSFRQ

12.11

-3.83

-1.34

FRKTKPPPPL

12.88

-5.65

-3.16
P38237

NFQIPSKPEN

13.31

-1.80

0.69

PFVPPPNVPK

14.78

-3.87

-1.38

IPSKPENTVN

14.81

-5.79

-3.30
P34223

MPDNEPKQGD

12.92

-4.61

-2.12

LEVTDPSDPN

13.89

-2.61

-0.12

EQPMPDNEPK

14.51

-4.86

-2.37
P53118

SVENPHDLPS

15.31

-3.72

-1.23

ENPHDLPSHL

15.51

-3.11

-0.62
P32389

MQNNHPFEPN

12.24

-2.97

-0.48

NHPFEPNFMG

12.49

-2.43

0.06

FMGSPSQFPA

12.84

-5.05

-2.56
P53933

RPPPPPIPST

12.28

-5.44

-2.95

PPPIPSTQKP

12.41

-7.10

-4.61

APPPLPNRQL

12.67

-5.49

-3.00
P32790

LPPIKPPRPT

8.07

-9.68

-7.19

IKPPRPTSTT

13.83

-3.51

-1.02

PPIKPPRPTS

14.08

-4.94

-2.45
P33400

SPQILPPLPV

10.51

-6.15

-3.66

QPPNAPSYQS

10.94

-5.49

-3.00

SYVQPPNAPS

15.38

-2.17

0.32
P23293

FPISPSQGQH

11.78

-5.33

-2.84

HQGSRPSHPQ

12.26

-4.21

-1.72

QFPISPSQGQ

12.63

-3.88

-1.39
Q04439

KPAPPPPGMQ

12.27

-7.38

-4.89

NIPTPPQNRD

13.19

-2.79

-0.30

SKPKEPMFEA

13.22

-3.28

-0.79
P33338

RTPARTPTPT

15.52

-3.27

-0.78

TPARTPARTP

15.66

-4.02

-1.53

PTPTPPVVAE

15.89

-2.89

-0.40
Q12446

FPFPVPQQQF

11.62

-6.10

-3.61

RPVPPPPPMR

11.73

-7.89

-5.40

LPPASPEVRK

11.96

-6.43

-3.94
P22219

SPGETPYLIT

15.69

-3.48

-0.99

NPDFPYNNSN

15.80

-4.35

-1.86
P53220

TRNKPKPLWP

15.60

-3.95

-1.46
Q12373

RPLSQPTTSI

12.50

-4.76

-2.27
P41695

TPVKPSLTSN

14.35

-5.52

-3.03

LAHETPVKPS

14.57

-4.37

-1.88

ETPVKPSLTS

15.63

-2.60

-0.11
Q00916

RPTDYPYAKR

10.02

-6.37

-3.88

FKPRPPLSYK

10.22

-4.78

-2.29

LFKPRPPLSY

10.72

-3.43

-0.94
P53901

DPIILPPTFS

9.61

-7.62

-5.13

LPPIPTRDDM

11.00

-6.76

-4.27

MRPIPPLPTE

12.35

-4.09

-1.60
P38990

RNQNLPKIPN

11.31

-3.93

-1.44

LPSAPSSTRL

13.10

-5.95

-3.46

SVPNLPSAPS

14.48

-2.94

-0.45
P47110

SKPNSPKETD

14.35

0.02

2.51

ATSTPPRKPS

15.35

-3.53

-1.04

KPNSPKETDS

15.41

-5.72

-3.23
P10566

IPAIPMDLPD

11.96

-8.02

-5.53

TRPIPAIPMD

12.85

-5.50

-3.01

RPIPAIPMDL

14.46

-5.89

-3.40
Q07821

PDSQRPGKKP

13.50

-3.17

-0.68
P25558

RHPKSPVKKP

10.64

-3.78

-1.29

LPNTPRSINV

13.12

-7.20

-4.71

SPVKKPMTSE

13.16

-5.50

-3.01
P40325

LPWTYPPRFY

8.44

-7.94

-5.45

RPQQNPSLPW

9.22

-7.08

-4.59

RPHQRPSTMP

9.43

-8.20

-5.71
P37370

VPQNRPHMPS

8.41

-6.53

-4.04

RPHMPSVRPA

9.71

-9.67

-7.18

SPSINPPKQS

10.03

-7.37

-4.88
Q08446

NSSHSPISPL

14.59

-3.73

-1.24
P47129

RKPNPPPNRS

9.66

-3.42

-0.93

KPNPPPNRSQ

12.97

-5.54

-3.05

TLPNRKPNPP

13.62

-4.63

-2.14
P53169

IMPTLPPRPY

11.78

-4.97

-2.48

SVPIMPTLPP

13.65

-3.57

-1.08

TANSVPIMPT

14.43

-4.40

-1.91

 


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