ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FYN-SSH-13.PDB
Scoring matrix: RVS167_FYN-SSH-13_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.52
Foldx random average score for Saccharomyces cerevisiae: 12.990

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1607984
Proteins after disorder filtering: 4634
 Total fragments: 80638
Proteins after pattern filtering: 2245
 Total fragments: 13773
Proteins after MINT filtering: 71
 Total fragments: 832


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

16.52

-2.86

0.00
Best peptides

RDWNRYWK

0.00

-6.89

-4.03
         
Interactors      
P38140

IPPHPYPS

8.90

-7.24

-4.38

QPDLPPRK

9.18

-9.50

-6.64

PDLPPRKI

9.56

-6.61

-3.75
Q06604

LLPTRPNK

7.36

-7.08

-4.22

LPTRPNKA

8.50

-9.56

-6.70

KPLLPTRP

8.92

-11.10

-8.24
Q12365

IPFIPPQE

7.70

-9.23

-6.37

VPREPLRN

10.61

-8.85

-5.99

QIPFIPPQ

11.82

-6.10

-3.24
P40072

PPTTKPGT

12.26

-5.48

-2.62

AAPPTTKP

12.86

-4.77

-1.91
P40956

NPKNVPFP

7.15

-9.18

-6.32

TPPLPRRR

8.65

-11.24

-8.38

PPLPRRRA

9.49

-8.07

-5.21
Q06833

RPVPRRPS

7.23

-8.65

-5.79

RRPVPRRP

7.65

-11.93

-9.07

RPSQPLNT

9.23

-8.56

-5.70
P40032

FPSILPNV

7.44

-7.08

-4.22

ILPNVPHS

9.34

-7.63

-4.77

LPNVPHSD

9.89

-7.30

-4.44
P32628

EPPIAPES

11.98

-6.63

-3.77

PPIAPESA

12.34

-5.48

-2.62
Q12242

KPCDVPNN

9.76

-6.63

-3.77
P38266

KPPVVPKK

6.77

-9.76

-6.90

VPPVVPKK

7.34

-9.27

-6.41

FPPPPLKP

7.71

-9.95

-7.09
P25333

YPEGAPTS

11.98

-6.78

-3.92

TPAPTPTA

12.14

-4.54

-1.68

DKYPEGAP

12.65

-2.66

0.20
P16603

LPSNPSTP

7.99

-7.30

-4.44

NPSTPVIM

8.54

-8.66

-5.80

LPDAPPVV

8.95

-8.21

-5.35
P39692

LPPSPKQP

9.48

-8.32

-5.46

MKLPPSPK

9.68

-5.99

-3.13

SPKQPVIM

10.39

-8.17

-5.31
P38872

CLPNLYPH

7.96

-4.65

-1.79

TLPLPNPY

10.26

-7.58

-4.72
P17555

GPPPRPKK

6.96

-8.19

-5.33

RPKKPSTL

8.97

-10.38

-7.52

PPPRPKKP

9.31

-9.74

-6.88
Q12344

SPPLPPRQ

9.63

-10.13

-7.27

SPKLPPRG

9.76

-9.16

-6.30

PLPPRQNV

10.25

-6.24

-3.38
P38289

DPENPSFI

9.03

-9.49

-6.63

YDVPTNDP

11.18

-3.37

-0.51

EDPENPSF

11.96

-3.57

-0.71
Q03780

RPPPPPMD

8.93

-12.67

-9.81

APDIPPRS

9.29

-9.49

-6.63

RSRPPPPP

10.22

-7.82

-4.96
P53316

VPPVPYII

7.17

-9.44

-6.58

IPQVPPVP

7.77

-8.43

-5.57

VPYIIPPQ

8.80

-8.40

-5.54
P32190

RPSTAPAR

11.07

-8.65

-5.79

RRPSTAPA

11.75

-5.99

-3.13
Q12389

EDPSQGPA

11.96

-3.21

-0.35
P13186

RPPIPAAL

7.18

-10.50

-7.64

IPAALPPS

9.69

-6.13

-3.27

IPLTPLAT

10.27

-6.63

-3.77
P12630

NPFCLPNS

8.84

-4.82

-1.96

PFCLPNSN

12.07

-5.84

-2.98
P39940

WDDPRLPS

8.48

-4.62

-1.76

DDPRLPSS

10.40

-4.22

-1.36

DPRLPSSL

10.74

-6.96

-4.10
P04051

NPAMLPGS

9.27

-5.98

-3.12

LPHFPKNS

9.31

-8.12

-5.26

DRSLPHFP

10.72

-10.45

-7.59
P43603

RFTAPTSP

9.81

-6.88

-4.02

APTSPSTS

11.92

-6.06

-3.20
P15891

TPEKKPKE

9.34

-7.17

-4.31

RATPEKKP

9.56

-7.71

-4.85

QPPLPSRN

9.70

-10.63

-7.77
P07278

TPPLPMHF

10.77

-9.82

-6.96

TSTPPLPM

12.65

-4.28

-1.42
P06777

LIPNEPDD

10.56

-4.84

-1.98

IPNEPDDI

11.12

-6.63

-3.77
P27999

SDPTLPRS

10.14

-5.54

-2.68

DPTLPRSD

11.13

-7.39

-4.53
P47029

KLPNLPND

8.16

-4.82

-1.96

LPRDPPSY

9.32

-6.94

-4.08

LPNLPNDA

9.97

-7.93

-5.07
Q12168

IPPPVPNR

8.61

-8.41

-5.55

PPPLPPRA

9.37

-10.49

-7.63

VQHPVPKP

9.79

-5.88

-3.02
Q04322

APLDRPQL

8.83

-6.84

-3.98

PPTLPPRR

9.64

-10.19

-7.33

SPPLPPRA

9.67

-10.43

-7.57
P08458

LPKRKPPK

8.69

-8.66

-5.80

NLPKRKPP

9.96

-6.57

-3.71

PKRKPPKL

10.24

-6.85

-3.99
Q02209

YKGPESKP

8.50

-4.74

-1.88

GPESKPNV

10.92

-6.22

-3.36

PESKPNVN

12.84

-7.49

-4.63
Q12496

IPSNIPKK

4.83

-8.29

-5.43

IPKKRPFL

7.42

-10.25

-7.39

PSNIPKKR

10.72

-7.76

-4.90
P32793

GPTHPSNM

10.75

-7.00

-4.14
P36006

IPPPPPPM

9.24

-8.43

-5.57

IPIPPPPP

9.48

-7.79

-4.93

KPKNPGGL

9.76

-7.44

-4.58
P32875

KPDPMEPE

11.23

-7.61

-4.75

TNRTPSKP

11.30

-5.08

-2.22

RTPSKPDP

11.56

-5.85

-2.99
Q08412

WQPLPPEP

9.53

-7.22

-4.36

LPTQPVRK

9.92

-9.53

-6.67

PPQLPTRT

10.24

-9.17

-6.31
Q06440

TPKVEPSK

9.68

-5.56

-2.70

RTPKVEPS

12.40

-6.64

-3.78

DRTPKVEP

12.62

-5.57

-2.71
P38750

LPHNLPHN

8.57

-8.23

-5.37

PPILPRTT

10.39

-8.00

-5.14

FPHNAPAS

10.53

-5.50

-2.64
P26570

PKSPILKT

9.30

-5.84

-2.98

DPSTPSKP

10.04

-7.65

-4.79

MEPKSPIL

10.96

-7.15

-4.29
P31374

RKTKPPPP

9.22

-8.55

-5.69

ISPERPSF

9.88

-4.37

-1.51

TPDDLPPL

9.92

-5.66

-2.80
P38237

PPPNVPKK

6.76

-7.77

-4.91

NFQIPSKP

8.45

-7.76

-4.90

NDPFVPPP

9.41

-5.78

-2.92
P34223

MPDNEPKQ

6.73

-7.05

-4.19

SPAEVPKN

9.96

-7.06

-4.20

PDNEPKQG

11.56

-6.03

-3.17
P53118

NPHDLPSH

9.35

-5.66

-2.80
P32389

HPFEPNFM

9.94

-10.57

-7.71

NHPFEPNF

12.97

-3.22

-0.36
P53933

RPPPPPIP

5.67

-11.64

-8.78

YPGNPTSR

7.81

-7.41

-4.55

RRPPPPPI

9.07

-8.51

-5.65
P32790

IKPPRPTS

7.80

-5.50

-2.64

LPPIKPPR

7.81

-10.91

-8.05

APLDPFKT

9.32

-7.31

-4.45
P33400

ILPPLPVG

8.51

-6.38

-3.52

LPPLPVGI

9.24

-8.39

-5.53

PPLPVGIS

9.84

-6.82

-3.96
P23293

RPSHPQFP

7.88

-11.20

-8.34

IPRGPKKD

9.11

-8.20

-5.34

FPISPSQG

10.17

-7.44

-4.58
Q04439

RPSPPTAA

8.97

-8.81

-5.95

IPPPPPPP

9.27

-8.15

-5.29

PPSSKPKE

9.95

-6.42

-3.56
P33338

TPTPPVVA

9.88

-7.35

-4.49

RTPARTPT

10.20

-5.87

-3.01

RTPTPTPP

11.56

-7.51

-4.65
Q12446

RPVPPPPP

8.32

-9.70

-6.84

LPPLPNQF

8.35

-9.78

-6.92

IPEIPSTQ

8.63

-8.20

-5.34
P22219

NPDFPYNN

9.52

-6.85

-3.99
P53220

NKPKPLWP

7.67

-8.96

-6.10
Q12373

RPLSQPTT

9.08

-7.38

-4.52

SKRPLSQP

11.16

-6.70

-3.84
P41695

HETPVKPS

12.53

-4.51

-1.65

AHETPVKP

12.66

-5.51

-2.65

ETPVKPSL

12.76

-5.11

-2.25
Q00916

LFKPRPPL

8.56

-5.92

-3.06

RLFKPRPP

9.47

-8.10

-5.24

KPRPPLSY

10.57

-6.96

-4.10
P53901

QPPLPPIP

7.56

-9.97

-7.11

NDPIILPP

7.78

-6.75

-3.89

LPPIPTRD

7.87

-11.25

-8.39
P38990

NQNLPKIP

8.57

-8.61

-5.75

PSPIRPVL

8.83

-6.31

-3.45

NLPKIPNS

10.11

-6.66

-3.80
P47110

TPPRKPSP

9.81

-6.64

-3.78

SKPNSPKE

10.32

-4.13

-1.27

TSTPPRKP

10.90

-6.12

-3.26
P10566

TRPIPAIP

7.85

-8.83

-5.97

IPAIPMDL

9.33

-7.34

-4.48

IPMDLPDY

10.12

-4.15

-1.29
P25693

RPIPTIKP

8.38

-8.77

-5.91
P25558

HPKSPVKK

8.79

-8.02

-5.16

PKSPVKKP

9.86

-5.99

-3.13

PNTPRSIN

10.33

-4.96

-2.10
P40325

RPPPRPQQ

6.07

-10.71

-7.85

RPHQRPST

7.91

-8.52

-5.66

RPSTMPAT

8.48

-9.34

-6.48
P37370

RPHMPSVR

6.01

-11.28

-8.42

MPKPRPFQ

6.66

-10.85

-7.99

APPIPDIP

7.71

-9.48

-6.62
P39743

YSNPLTSP

10.99

-4.04

-1.18

NPLTSPVA

11.88

-5.03

-2.17
P47129

RKPNPPPN

6.59

-7.73

-4.87

TLPNRKPN

7.79

-5.01

-2.15

LPNRKPNP

8.87

-8.14

-5.28
P53169

MPTLPPRP

7.57

-11.16

-8.30

IMPTLPPR

10.03

-6.38

-3.52

VPIMPTLP

11.11

-10.30

-7.44

 


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