ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-9.PDB
Scoring matrix: RVS167_FMK-SSH-9_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.01
Foldx random average score for Saccharomyces cerevisiae: 11.102

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1548210
Proteins after disorder filtering: 4550
 Total fragments: 67350
Proteins after pattern filtering: 2166
 Total fragments: 12122
Proteins after MINT filtering: 71
 Total fragments: 777


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.01

-3.46

0.00
Best peptides

YRYIHPWK

0.00

-6.48

-3.02
         
Interactors      
P38140

QPDLPPRK

7.42

-7.70

-4.24

MNIQPDLP

8.16

-8.62

-5.16

NIPPHPYP

8.37

-5.77

-2.31
Q06604

LLPTRPNK

6.73

-8.09

-4.63

LPTRPNKA

7.83

-8.49

-5.03

FEKGPRMP

8.00

-9.10

-5.64
Q12365

IPFIPPQE

6.94

-8.98

-5.52

VPREPLRN

7.40

-7.69

-4.23

IVPREPLR

9.65

-6.58

-3.12
P40072

TPSASPML

9.87

-3.69

-0.23

APPTTKPG

10.78

-4.71

-1.25
P40956

TPPLPRRR

9.21

-7.12

-3.66

PPLPRRRA

9.23

-9.16

-5.70

NPKNVPFP

9.34

-5.06

-1.60
Q06833

RRPVPRRP

3.84

-11.31

-7.85

RRPSQPLN

6.75

-6.17

-2.71

RPSQPLNT

7.83

-5.99

-2.53
P40032

FPSILPNV

6.55

-4.72

-1.26

RLFPSILP

7.41

-7.73

-4.27

LPNVPHSD

9.15

-7.12

-3.66
P32628

EPPIAPES

8.85

-5.71

-2.25
Q12242

KPCDVPNN

10.19

-4.36

-0.90
P38266

KPPVVPKK

5.00

-8.19

-4.73

VPPVVPKK

5.91

-10.00

-6.54

FPPPPLKP

6.18

-8.20

-4.74
P25333

YPEGAPTS

9.84

-6.25

-2.79
P53169

ANSVPIMP

7.97

-8.68

-5.22

MPTLPPRP

8.15

-9.20

-5.74

VPIMPTLP

8.32

-6.31

-2.85
P39692

KLPPSPKQ

8.39

-6.62

-3.16

LPPSPKQP

8.39

-8.26

-4.80

MKLPPSPK

9.25

-7.26

-3.80
P38872

CLPNLYPH

10.34

-5.51

-2.05
P17555

GPPPRPKK

7.57

-7.74

-4.28

RPKKPSTL

7.62

-7.35

-3.89

PPPRPKKP

7.78

-7.89

-4.43
Q12344

SPPLPPRQ

9.62

-7.63

-4.17

SPKLPPRG

10.29

-5.75

-2.29

TSPKLPPR

10.68

-5.70

-2.24
P38289

DPENPSFI

8.68

-6.37

-2.91

YDVPTNDP

10.23

-4.99

-1.53

EDPENPSF

11.01

-3.84

-0.38
Q03780

RPPPPPMD

6.13

-10.42

-6.96

APDIPPRS

6.66

-9.48

-6.02

PPPPMDMK

6.84

-8.62

-5.16
P53316

VPYIIPPQ

7.30

-9.87

-6.41

VPPVPYII

7.33

-7.04

-3.58

MPMFPSFG

7.58

-6.40

-2.94
P32190

RPSTAPAR

8.80

-7.24

-3.78

RRPSTAPA

9.20

-4.31

-0.85

LRRPSTAP

9.76

-3.84

-0.38
P13186

RPPIPAAL

6.18

-9.91

-6.45

PSYVPNRV

8.45

-9.62

-6.16

QNNIPLTP

9.06

-7.83

-4.37
P12630

NPFCLPNS

10.91

-5.06

-1.60
P39940

WDDPRLPS

8.93

-7.04

-3.58

TWDDPRLP

9.34

-8.20

-4.74

DDPRLPSS

10.10

-5.32

-1.86
P04051

RSLPHFPK

7.44

-6.76

-3.30

DRSLPHFP

9.09

-6.97

-3.51

LPHFPKNS

9.10

-6.91

-3.45
P43603

RFTAPTSP

10.36

-7.71

-4.25
P15891

APPPPPRR

7.80

-8.26

-4.80

TPEKKPKE

8.62

-5.23

-1.77

PPPPPRRA

8.67

-8.63

-5.17
P07278

KTSTPPLP

7.70

-6.92

-3.46

STPPLPMH

10.05

-7.02

-3.56

TPPLPMHF

10.81

-4.88

-1.42
P06777

IPNEPDDI

9.73

-6.72

-3.26
P27999

SDPTLPRS

8.48

-7.21

-3.75

IGSDPTLP

9.79

-5.88

-2.42
P47029

LPRDPPSY

6.98

-6.20

-2.74

HPTPPSLK

7.85

-7.15

-3.69

PRDPPSYK

7.91

-7.13

-3.67
Q12168

PPPVPNRP

7.28

-9.78

-6.32

DPYFPQFR

7.74

-7.79

-4.33

NRGPPPLP

8.57

-6.78

-3.32
Q04322

APLDRPQL

8.82

-6.00

-2.54

PPTLPPRR

9.44

-8.65

-5.19

SPPLPPRA

9.48

-7.76

-4.30
P08458

LPKRKPPK

7.10

-6.94

-3.48

PKRKPPKL

7.62

-7.50

-4.04

NLPKRKPP

9.20

-7.76

-4.30
Q02209

YKGPESKP

9.64

-6.50

-3.04

PESKPNVN

11.03

-6.82

-3.36
Q12496

IPKKRPFL

6.15

-9.18

-5.72

IPSNIPKK

6.49

-7.48

-4.02

PSNIPKKR

8.42

-10.12

-6.66
P32793

HGPTHPSN

10.73

-5.54

-2.08
P36006

QPKDPKFE

8.09

-7.53

-4.07

PPPPPPMG

8.38

-7.55

-4.09

GQPKDPKF

8.63

-6.90

-3.44
P32875

TNRTPSKP

9.52

-7.88

-4.42

KPDPMEPE

9.57

-5.94

-2.48

RTPSKPDP

9.89

-4.70

-1.24
Q08412

LPTQPVRK

6.11

-6.40

-2.94

KNSRPQQP

8.78

-7.42

-3.96

LPPEPLDT

8.79

-5.13

-1.67
Q06440

RTPKVEPS

8.91

-6.73

-3.27
P38750

LGLPHNLP

9.20

-4.84

-1.38

LPHNLPHN

9.78

-4.82

-1.36

RSPPGVFP

10.03

-6.98

-3.52
P26570

MEPKSPIL

8.17

-5.84

-2.38

EPKSPILK

8.45

-6.67

-3.21

DPSTPSKP

8.93

-6.42

-2.96
P31374

KPGTPVFP

6.85

-6.96

-3.50

RKTKPPPP

7.53

-9.91

-6.45

PDDLPPLK

7.91

-8.56

-5.10
P38237

PPPNVPKK

8.01

-7.68

-4.22

NFQIPSKP

8.66

-7.35

-3.89

PPNVPKKD

8.75

-7.90

-4.44
P34223

PDNEPKQG

9.77

-6.79

-3.33

SPAEVPKN

9.96

-4.79

-1.33

MPDNEPKQ

10.63

-5.98

-2.52
P53118

VENPHDLP

8.42

-6.16

-2.70

NPHDLPSH

10.46

-4.48

-1.02
P32389

HPFEPNFM

7.63

-9.53

-6.07

MGSPSQFP

10.60

-3.95

-0.49

QNNHPFEP

10.97

-6.19

-2.73
P53933

RPPPPPIP

6.51

-10.25

-6.79

RRRPPPPP

6.86

-9.34

-5.88

RRPPPPPI

6.96

-8.79

-5.33
P32790

LPPIKPPR

6.30

-8.08

-4.62

PPIKPPRP

7.67

-7.87

-4.41

PPAMPARP

7.97

-7.52

-4.06
P33400

ILPPLPVG

9.57

-5.87

-2.41

LPPLPVGI

9.90

-7.95

-4.49

SPQILPPL

9.94

-5.80

-2.34
P23293

RPSHPQFP

6.55

-9.15

-5.69

SRPSHPQF

8.46

-4.76

-1.30

FPISPSQG

8.92

-5.29

-1.83
Q04439

KPKEPMFE

7.12

-7.25

-3.79

APPPPGMQ

8.58

-7.77

-4.31

IPPPPPPP

8.86

-7.93

-4.47
P33338

RTPTPTPP

8.82

-7.55

-4.09

PARTPART

9.21

-8.32

-4.86

RTPARTPT

9.81

-7.18

-3.72
Q12446

FPFPIPEI

7.28

-4.09

-0.63

VPPPPPMR

7.30

-7.03

-3.57

RLPAPPPP

7.80

-8.00

-4.54
P22219

SPGETPYL

9.95

-4.17

-0.71

PGETPYLI

10.18

-6.41

-2.95

NPDFPYNN

11.02

-6.35

-2.89
P53220

NKPKPLWP

7.21

-6.25

-2.79
Q12373

RPLSQPTT

9.55

-6.10

-2.64

KRPLSQPT

10.30

-5.18

-1.72

SKRPLSQP

10.78

-6.07

-2.61
P41695

AHETPVKP

8.59

-5.86

-2.40

TPVKPSLT

9.31

-5.24

-1.78

ETPVKPSL

10.17

-5.14

-1.68
Q00916

FKPRPPLS

5.48

-9.27

-5.81

RLFKPRPP

7.04

-8.45

-4.99

YKRPTDYP

7.20

-6.50

-3.04
P53901

MRPIPPLP

4.34

-9.49

-6.03

LPPIPTRD

5.97

-9.19

-5.73

NDPIILPP

7.76

-6.89

-3.43
P38990

VSSVPNLP

8.35

-7.94

-4.48

PSPIRPVL

8.58

-7.33

-3.87

SPIRPVLP

9.06

-6.88

-3.42
P47110

PPRKPSPV

9.35

-8.92

-5.46

KPNSPKET

9.93

-4.77

-1.31

TPPRKPSP

10.02

-6.60

-3.14
P10566

TRPIPAIP

7.49

-7.59

-4.13

IPAIPMDL

8.17

-5.35

-1.89

IPMDLPDY

9.11

-3.58

-0.12
P25693

RPIPTIKP

8.13

-7.21

-3.75
P25558

RHPKSPVK

5.81

-5.99

-2.53

HPKSPVKK

8.44

-8.59

-5.13

SPVKKPMT

8.71

-5.71

-2.25
P40325

QPPRPPRP

6.52

-8.23

-4.77

RPPPRPQQ

6.90

-7.56

-4.10

QPRPPPRP

7.38

-7.23

-3.77
P37370

APPIPGMG

6.35

-8.54

-5.08

APPIPDIP

7.12

-7.87

-4.41

RPHMPSVR

7.26

-11.35

-7.89
Q08446

HSPISPLK

6.02

-6.93

-3.47
P39743

YSNPLTSP

10.48

-6.55

-3.09

NPLTSPVA

10.90

-3.12

0.34
P47129

LPNRKPNP

8.31

-5.48

-2.02

RKPNPPPN

8.42

-7.53

-4.07

KPNPPPNR

9.28

-6.33

-2.87
P16603

LPDAPPVV

9.05

-4.59

-1.13

NFPNPELP

9.33

-6.51

-3.05

LPSNPSTP

9.36

-6.87

-3.41

 


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