ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-8.PDB
Scoring matrix: RVS167_FMK-SSH-8_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 14.62
Foldx random average score for Saccharomyces cerevisiae: 12.763

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1937174
Proteins after disorder filtering: 4732
 Total fragments: 124518
Proteins after pattern filtering: 2318
 Total fragments: 18428
Proteins after MINT filtering: 73
 Total fragments: 1132


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

14.62

-2.33

0.00
Best peptides

RWPRLPRF

0.00

-9.15

-6.83
         
Interactors      
P38140

IQPDLPPR

5.62

-8.68

-6.35

QPDLPPRK

7.27

-7.96

-5.63

NIPPHPYP

8.67

-4.59

-2.26
Q06604

SPPPLPTR

4.45

-10.44

-8.11

KGPRMPSR

5.02

-10.55

-8.23

EKPLLPTR

5.89

-9.61

-7.28
Q12365

IVPREPLR

4.79

-7.22

-4.89

QIPFIPPQ

6.27

-5.42

-3.09

PREPLRNE

8.01

-5.92

-3.59
P40072

TPSASPML

8.64

-6.58

-4.25

PPTTKPGT

9.20

-7.22

-4.89

APPTTKPG

10.40

-6.36

-4.04
P40956

STPPLPRR

5.44

-7.35

-5.02

WNPKNVPF

7.62

-7.03

-4.71

FWNPKNVP

8.05

-4.34

-2.01
Q06833

PVPRRPSQ

4.45

-7.05

-4.72

RRPSQPLN

7.70

-7.41

-5.09

PRRPSQPL

7.77

-5.46

-3.13
P40032

FPSILPNV

7.87

-7.57

-5.25

VPHSDPSA

8.49

-5.36

-3.04

SILPNVPH

11.27

-3.64

-1.31
P32628

EPPIAPES

9.91

-7.14

-4.81

PPIAPESA

10.66

-4.68

-2.35
Q12242

KPCDVPNN

9.83

-7.56

-5.23

TKPCDVPN

11.93

-5.18

-2.85

GTKPCDVP

12.08

-2.06

0.27
P38266

AVPILPPR

4.71

-7.86

-5.54

MPPPKPFR

4.96

-9.81

-7.49

QPPPKPFR

4.96

-9.61

-7.28
P25333

TPAPTPTA

10.03

-6.59

-4.26

AITPAPTP

10.06

-4.31

-1.98

YPEGAPTS

11.07

-5.63

-3.30
P16603

PNPELPDA

7.21

-5.99

-3.67

SNPSTPVI

7.59

-5.76

-3.43

LPDAPPVV

9.01

-5.77

-3.44
P39692

PSPKQPVI

8.31

-7.00

-4.67

VMKLPPSP

8.84

-7.31

-4.98

PPSPKQPV

9.29

-5.11

-2.79
P38872

GTLPLPNP

8.49

-8.17

-5.84

LPNLYPHG

10.29

-5.61

-3.29

TLPLPNPY

12.00

-6.80

-4.47
P17555

GPPPRPKK

4.68

-10.09

-7.76

PRPKKPST

6.36

-8.37

-6.04

PPPPPPAP

7.60

-8.91

-6.59
Q12344

SSPPLPPR

5.66

-9.21

-6.89

TSPKLPPR

5.92

-8.76

-6.43

SPPLPPRQ

7.44

-8.48

-6.16
P38289

EDPENPSF

6.25

-7.00

-4.67

VPTNDPSG

10.16

-5.68

-3.35

DVPTNDPS

10.50

-1.97

0.36
Q03780

SRPPPPPM

4.80

-9.17

-6.84

IPPRSPNR

5.81

-10.14

-7.82

PPPPPMDM

6.57

-9.27

-6.94
P53316

MMPMFPSF

5.58

-8.68

-6.35

QVPPVPYI

5.78

-7.04

-4.71

VPYIIPPQ

7.61

-8.43

-6.10
P32190

RPSTAPAR

8.69

-7.16

-4.84

RRPSTAPA

10.60

-5.11

-2.79

LRRPSTAP

10.65

-2.39

-0.06
Q12389

LEDPSQGP

11.18

-3.37

-1.04

DPSQGPAA

11.33

-5.15

-2.83
P13186

APSYVPNR

6.62

-8.60

-6.27

NNIPLTPL

6.82

-5.95

-3.63

LPEREPPT

7.13

-6.82

-4.50
P12630

NPFCLPNS

9.16

-7.85

-5.52

SNPFCLPN

10.82

-5.47

-3.14

SSNPFCLP

12.29

-3.29

-0.96
P39940

DDPRLPSS

6.95

-8.21

-5.89

TWDDPRLP

8.94

-5.98

-3.66

DPRLPSSL

10.05

-6.20

-3.88
P04051

SVNPAMLP

9.17

-4.58

-2.25

NPAMLPGS

9.76

-7.91

-5.59

PHFPKNSK

10.09

-4.59

-2.26
P43603

TAPTSPST

10.16

-4.99

-2.67
P15891

AQPPLPSR

4.65

-9.02

-6.69

APPPPPRR

5.67

-10.60

-8.27

AAPPPPPR

6.55

-8.74

-6.42
P07278

STPPLPMH

6.53

-6.69

-4.37

TPPLPMHF

6.90

-8.48

-6.16

KTSTPPLP

11.64

-5.09

-2.76
P06777

PNEPDDIE

10.02

-0.98

1.35

LIPNEPDD

10.34

-2.62

-0.29

IPNEPDDI

10.39

-3.22

-0.90
P27999

SDPTLPRS

8.77

-8.51

-6.18

PTLPRSDR

10.63

-4.94

-2.62

GSDPTLPR

11.08

-6.17

-3.84
P47029

KGPKLPNL

5.55

-9.03

-6.70

LPRDPPSY

7.16

-8.48

-6.16

KHPTPPSL

7.74

-7.66

-5.34
Q12168

GPPPLPPR

3.81

-10.87

-8.54

IPPPVPNR

5.51

-10.02

-7.69

HPVPKPNI

6.12

-8.94

-6.61
Q04322

TPPTLPPR

5.10

-10.65

-8.32

TSPPLPPR

5.69

-9.30

-6.98

APLDRPQL

6.68

-8.26

-5.93
P08458

LPKRKPPK

4.96

-9.46

-7.14

PKRKPPKL

6.96

-7.67

-5.34

TNLPKRKP

9.05

-8.10

-5.77
Q02209

GPESKPNV

8.34

-7.14

-4.81

KGPESKPN

11.00

-4.28

-1.96

YKGPESKP

12.61

-2.76

-0.43
Q12496

IPKKRPFL

5.39

-8.29

-5.96

NIPKKRPF

6.48

-3.26

-0.93

SNIPKKRP

7.64

-6.61

-4.29
P32793

HGPTHPSN

10.17

-5.42

-3.09

GPTHPSNM

11.20

-4.91

-2.59
P36006

GQPKDPKF

4.68

-7.14

-4.81

IPPPPPPM

5.27

-9.75

-7.42

ANIPIPPP

6.36

-7.84

-5.51
P32875

KPDPMEPE

6.82

-4.59

-2.26

RTPSKPDP

9.08

-6.51

-4.18

PSKPDPME

9.21

-4.36

-2.04
Q08412

KWQPLPPE

3.81

-8.40

-6.08

VPPQLPTR

5.65

-9.65

-7.33

QPLPPEPL

7.47

-5.01

-2.68
Q06440

TPKVEPSK

7.74

-7.56

-5.23

RTPKVEPS

9.87

-3.22

-0.90

DRTPKVEP

10.84

-4.51

-2.18
P38750

LPHNLPHN

7.49

-7.66

-5.34

APASSPAY

8.59

-5.89

-3.56

PPGVFPVR

9.53

-5.64

-3.31
P26570

STPSKPNL

7.43

-5.34

-3.01

MEPKSPIL

7.51

-6.75

-4.42

PDPSTPSK

8.64

-6.24

-3.92
P31374

TPDDLPPL

5.04

-8.27

-5.94

EQPRLPST

5.64

-8.48

-6.16

ISPERPSF

6.04

-6.73

-4.41
P38237

PPPNVPKK

6.80

-10.15

-7.83

NDPFVPPP

8.23

-7.33

-5.00

QIPSKPEN

8.65

-4.39

-2.06
P34223

PMPDNEPK

6.79

-5.18

-2.85

MPDNEPKQ

7.64

-5.99

-3.67

SPAEVPKN

9.41

-7.38

-5.05
P53118

NPHDLPSH

6.51

-7.90

-5.58

PHDLPSHL

11.11

-3.47

-1.15

VENPHDLP

11.58

-1.48

0.85
P32389

NHPFEPNF

6.16

-8.99

-6.67

NNHPFEPN

8.51

-2.49

-0.17

PPSPAETR

8.95

-4.03

-1.71
P53933

APPPLPNR

4.28

-10.71

-8.39

RRPPPPPI

5.52

-8.44

-6.11

TRRRPPPP

6.55

-7.36

-5.04
P32790

LPPIKPPR

5.60

-10.16

-7.84

PPPAMPAR

5.66

-10.65

-8.32

APAPLDPF

6.93

-6.20

-3.88
P33400

SPQILPPL

4.96

-8.47

-6.15

QPPNAPSY

6.96

-8.68

-6.35

PQILPPLP

9.74

-6.81

-4.48
P23293

SRPSHPQF

5.99

-8.48

-6.16

AIPRGPKK

6.80

-5.26

-2.93

QFPISPSQ

8.63

-7.13

-4.80
Q04439

SKPKEPMF

5.42

-9.33

-7.00

PAPPPPGM

6.57

-8.38

-6.06

NNIPTPPQ

6.76

-6.83

-4.50
P33338

TPARTPAR

6.88

-9.09

-6.76

TPTPTPPV

8.19

-6.62

-4.29

ARTPTPTP

8.22

-6.74

-4.42
Q12446

APPPPPAF

5.00

-10.22

-7.90

PVPPPPPM

5.29

-8.18

-5.85

APPPPPRR

5.67

-10.60

-8.27
P22219

SPGETPYL

8.67

-5.99

-3.67

VSPGETPY

10.50

-3.06

-0.73

AVSPGETP

10.57

-2.47

-0.15
P53220

NKPKPLWP

12.17

-5.98

-3.66
Q12373

RPLSQPTT

9.59

-7.55

-5.22

SKRPLSQP

9.96

-6.91

-4.59

KRPLSQPT

10.09

-4.58

-2.25
P41695

ETPVKPSL

7.05

-6.25

-3.92

HETPVKPS

10.68

-3.66

-1.34

TPVKPSLT

11.93

-5.11

-2.79
Q00916

LFKPRPPL

5.41

-8.06

-5.74

PRPPLSYK

7.11

-7.75

-5.42

FKPRPPLS

8.11

-6.84

-4.51
P53901

AMRPIPPL

4.23

-8.95

-6.62

NQPPLPPI

5.06

-9.08

-6.75

NSPKLPPL

5.64

-8.72

-6.40
P38990

PSPIRPVL

7.30

-7.76

-5.43

SVPNLPSA

7.47

-6.52

-4.19

QPSPIRPV

8.92

-5.99

-3.67
P47110

TPPRKPSP

5.62

-10.05

-7.73

STPPRKPS

9.44

-3.48

-1.15

SKPNSPKE

9.61

-6.98

-4.66
P10566

IPMDLPDY

6.26

-8.89

-6.57

RPIPAIPM

9.12

-7.06

-4.73

PIPAIPMD

9.32

-3.52

-1.19
P25693

RPIPTIKP

10.74

-6.74

-4.42
Q07821

SQRPGKKP

10.41

-4.18

-1.85
P25558

SPVKKPMT

7.65

-7.76

-5.43

KSPVKKPM

7.90

-6.51

-4.18

RHPKSPVK

8.02

-7.80

-5.47
P40325

PWTYPPRF

4.04

-9.94

-7.61

SQPPRPPR

4.94

-9.21

-6.89

RPPPRPQQ

5.29

-9.40

-7.08
P37370

AAPPLPTF

4.18

-9.95

-7.62

SAPPIPGM

5.35

-9.62

-7.29

PPPPPPAL

5.76

-9.77

-7.44
Q08446

HSPISPLK

9.35

-6.35

-4.02

SHSPISPL

9.69

-5.40

-3.08
P39743

YSNPLTSP

10.57

-5.16

-2.84

SNPLTSPV

10.72

-3.11

-0.78

NPLTSPVA

11.25

-5.90

-3.58
P47129

GPPLLPPR

4.76

-10.62

-8.29

LPNRKPNP

6.37

-7.27

-4.94

KPNPPPNR

6.77

-7.56

-5.23
P53169

IMPTLPPR

4.54

-10.23

-7.91

SVPIMPTL

5.37

-7.66

-5.34

MPTLPPRP

9.45

-8.58

-6.25

 


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