ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-28.PDB
Scoring matrix: RVS167_FMK-SSH-28_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 16.55
Foldx random average score for Saccharomyces cerevisiae: 13.642

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1521600
Proteins after disorder filtering: 4208
 Total fragments: 48294
Proteins after pattern filtering: 2016
 Total fragments: 9653
Proteins after MINT filtering: 65
 Total fragments: 617


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

16.55

-2.33

0.00
Best peptides

RRTMWPMKRM

0.00

-9.81

-7.48
         
Interactors      
P38140

QPDLPPRKIM

9.59

-9.30

-6.97

IQPDLPPRKI

11.25

-6.37

-4.04

PDLPPRKIMI

11.64

-6.74

-4.41
Q06604

KPLLPTRPNK

8.36

-8.69

-6.36

KPTPPSPPAK

9.39

-8.73

-6.40

NEEKPLLPTR

9.79

-7.79

-5.46
Q12365

IPGKFPSPLT

9.90

-6.27

-3.94

IVPREPLRNE

11.28

-6.55

-4.22

IPFIPPQEDD

11.71

-7.21

-4.88
P40072

PPTTKPGTNS

12.73

-7.12

-4.79

PTTKPGTNSK

13.13

-6.64

-4.31
P40956

PPLPRRRATT

10.12

-7.77

-5.44

STPPLPRRRA

10.64

-5.93

-3.60

TSTPPLPRRR

11.09

-7.09

-4.76
Q06833

RRPVPRRPSQ

7.83

-8.80

-6.47

RRPSQPLNTL

8.24

-7.32

-4.99

FPVPPSASNM

9.65

-9.37

-7.04
P40032

RLFPSILPNV

10.40

-5.43

-3.10

FPSILPNVPH

11.01

-7.68

-5.35

LRLFPSILPN

12.53

-6.53

-4.20
P32628

EPPIAPESAT

12.86

-6.76

-4.43
P22219

PDFPYNNSNY

10.89

-7.16

-4.83

NPDFPYNNSN

13.63

-6.96

-4.63
P38266

LPPPKPFRHT

8.59

-9.33

-7.00

QPPPKPFRRS

8.59

-8.65

-6.32

MPPPKPFRHG

8.61

-8.24

-5.91
P25333

YPEGAPTSGA

12.69

-6.56

-4.23
P16603

LPSNPSTPVI

12.34

-7.89

-5.56

NPSTPVIMIG

12.34

-7.47

-5.14

NFPNPELPDA

12.53

-6.36

-4.03
P39692

PPSPKQPVIM

10.55

-8.85

-6.52

LPPSPKQPVI

11.45

-8.00

-5.67

PSPKQPVIMS

12.38

-4.00

-1.67
P38872

LPNLYPHGTL

11.09

-5.59

-3.26

CLPNLYPHGT

13.10

-5.61

-3.28

NCLPNLYPHG

13.21

-3.86

-1.53
P17555

KSGPPPRPKK

9.64

-6.88

-4.55

PRPKKPSTLK

9.69

-7.57

-5.24

RPKKPSTLKT

9.79

-8.37

-6.04
Q12344

TSPKLPPRGK

10.53

-6.01

-3.68

PPLPPRQNVA

11.74

-8.12

-5.79

PKLPPRGKQR

11.90

-6.43

-4.10
P38289

DPENPSFINY

10.47

-8.20

-5.87

EDPENPSFIN

12.12

-5.38

-3.05
Q03780

RPPPPPMDMK

6.30

-9.95

-7.62

RSRPPPPPMD

10.41

-6.65

-4.32

KRSRPPPPPM

11.01

-7.90

-5.57
P53316

MMPMFPSFGF

8.97

-7.31

-4.98

MPMFPSFGFI

10.72

-7.35

-5.02

IPPQNPAANH

11.88

-6.84

-4.51
P32190

RRPSTAPARE

10.92

-5.70

-3.37

LRRPSTAPAR

12.72

-6.12

-3.79

RPSTAPARET

13.11

-6.24

-3.91
Q12389

EDPSQGPAAN

12.68

-4.63

-2.30
P13186

PLPEREPPTY

9.52

-7.10

-4.77

IPAALPPSDM

10.43

-8.10

-5.77

NSSIPMSPNY

10.82

-4.75

-2.42
P12630

NPFCLPNSNT

10.58

-5.93

-3.60

SSNPFCLPNS

11.91

-5.84

-3.51
P39940

DDPRLPSSLD

11.13

-5.75

-3.42

WDDPRLPSSL

11.29

-7.00

-4.67
P04051

RSLPHFPKNS

9.56

-5.03

-2.70

DRSLPHFPKN

10.78

-6.24

-3.91

NPAMLPGSSN

10.94

-7.14

-4.81
P43603

RFTAPTSPST

11.76

-5.10

-2.77
P15891

RATPEKKPKE

9.60

-5.35

-3.02

RRATPEKKPK

10.28

-6.93

-4.60

QPPLPSRNVA

10.50

-8.59

-6.26
P07278

KTSTPPLPMH

12.05

-7.21

-4.88

TSTPPLPMHF

12.42

-5.42

-3.09
P47129

RKPNPPPNRS

8.50

-9.00

-6.67

PPLLPPRNTM

9.95

-9.26

-6.93

GPPLLPPRNT

10.52

-6.17

-3.84
P27999

DPTLPRSDRE

10.85

-8.20

-5.87

SDPTLPRSDR

11.62

-5.71

-3.38

IGSDPTLPRS

12.82

-6.85

-4.52
P47029

HPTPPSLKAS

10.25

-7.40

-5.07

YDGHPASFPK

11.47

-5.66

-3.33

KLPNLPNDAN

11.55

-5.47

-3.14
Q12168

RGPPPLPPRA

10.05

-6.53

-4.20

DDPYFPQFRS

10.39

-4.61

-2.28

GPPPLPPRAN

11.15

-7.59

-5.26
P08458

NLPKRKPPKL

9.51

-7.59

-5.26

LPKRKPPKLQ

9.82

-7.47

-5.14

PKRKPPKLQG

11.47

-6.54

-4.21
Q02209

YKGPESKPNV

10.50

-5.02

-2.69

GPESKPNVNF

12.47

-6.13

-3.80

PESKPNVNFM

12.86

-6.79

-4.46
Q12496

SNIPKKRPFL

13.10

-5.17

-2.84

PSNIPKKRPF

13.59

-5.00

-2.67

EIPSNIPKKR

13.63

-5.37

-3.04
P36006

IPPPPPPMGQ

10.98

-8.66

-6.33

KKPKNPGGLS

11.70

-6.05

-3.72

PKDPKFEAAY

11.91

-6.75

-4.42
P32875

RTPSKPDPME

11.19

-4.33

-2.00

NRTPSKPDPM

13.29

-5.23

-2.90
Q08412

VPPQLPTRTK

9.59

-7.97

-5.64

EDVPPQLPTR

9.80

-7.63

-5.30

KKKWQPLPPE

11.23

-4.92

-2.59
Q06440

DRTPKVEPSK

10.40

-6.48

-4.15
P38750

RSPPGVFPVR

9.19

-7.00

-4.67

PPGVFPVRGM

10.65

-7.95

-5.62

LGLPHNLPHN

12.17

-5.98

-3.65
P26570

YSTPLNSPGL

10.40

-6.08

-3.75

PKSPILKTNN

10.87

-5.37

-3.04

TPSKPNLEVN

10.94

-7.07

-4.74
P31374

RKTKPPPPLD

7.29

-6.75

-4.42

ISPERPSFRQ

9.80

-6.34

-4.01

TKPPPPLDFE

10.58

-6.57

-4.24
P38237

IPSKPENTVN

10.77

-7.29

-4.96

FVPPPNVPKK

10.82

-7.62

-5.29

NDPFVPPPNV

11.44

-6.20

-3.87
P34223

EQPMPDNEPK

13.08

-6.80

-4.47
P53118

NPHDLPSHLG

12.76

-5.28

-2.95

VENPHDLPSH

12.80

-6.89

-4.56
P32389

NNHPFEPNFM

10.76

-5.27

-2.94

HPFEPNFMGS

11.52

-7.18

-4.85

QNNHPFEPNF

12.36

-5.88

-3.55
P53933

RVAPPPLPNR

8.53

-8.31

-5.98

RPPPPPIPST

8.77

-9.03

-6.70

RRPPPPPIPS

10.90

-7.13

-4.80
P32790

IKPPRPTSTT

9.79

-7.63

-5.30

PPAMPARPTA

10.21

-8.26

-5.93

PPIKPPRPTS

11.10

-7.45

-5.12
P33400

ILPPLPVGIS

10.68

-6.65

-4.32

PQILPPLPVG

12.04

-6.42

-4.09

YVQPPNAPSY

12.22

-7.80

-5.47
P23293

RPSHPQFPIS

8.54

-7.60

-5.27

NKVPLPLGPQ

11.50

-5.39

-3.06

VPLPLGPQSR

11.77

-7.28

-4.95
Q04439

RPSPPTAATR

9.38

-8.38

-6.05

APPPPGMQNK

9.51

-9.28

-6.95

KKPAPPPPGM

9.74

-8.08

-5.75
P33338

RTPTPTPPVV

11.77

-6.30

-3.97

VTPARTPART

11.91

-5.96

-3.63

RTPARTPTPT

12.64

-4.90

-2.57
Q12446

RPLPQLPNRN

7.82

-7.17

-4.84

RPVPPPPPMR

8.47

-9.29

-6.96

NRPLPQLPNR

8.55

-7.79

-5.46
Q04322

TPPTLPPRRI

11.28

-8.94

-6.61

DQAPLDRPQL

12.30

-5.36

-3.03

TSPPLPPRAD

12.49

-5.83

-3.50
Q12373

RPLSQPTTSI

11.42

-5.89

-3.56

SKRPLSQPTT

11.98

-4.58

-2.25

KRPLSQPTTS

12.49

-5.74

-3.41
P41695

TPVKPSLTSN

12.19

-7.46

-5.13

HETPVKPSLT

12.92

-5.10

-2.77

ETPVKPSLTS

13.10

-3.45

-1.12
P53901

MRPIPPLPTE

6.88

-8.73

-6.40

NDPIILPPTF

8.65

-7.30

-4.97

LPPIPTRDDM

9.16

-9.84

-7.51
P38990

NQNLPKIPNS

11.51

-5.83

-3.50

NQPSPIRPVL

11.87

-6.08

-3.75

RNQNLPKIPN

12.04

-5.96

-3.63
Q00916

FKPRPPLSYK

6.96

-8.87

-6.54

RPTDYPYAKR

7.44

-7.48

-5.15

RLFKPRPPLS

8.61

-7.31

-4.98
P10566

TRPIPAIPMD

11.14

-7.13

-4.80

RPIPAIPMDL

12.70

-7.43

-5.10

PAIPMDLPDY

13.30

-7.38

-5.05
P25558

SPVKKPMTSE

10.42

-6.93

-4.60

PNTPRSINVT

10.84

-4.90

-2.57

KSPVKKPMTS

10.99

-5.54

-3.21
P40325

RPPRPAANLA

9.36

-8.77

-6.44

QPPRPPRPAA

10.08

-8.58

-6.25

LPWTYPPRFY

10.22

-7.74

-5.41
P37370

MPKPRPFQNK

7.51

-9.18

-6.85

RPSPISPSIN

8.93

-9.53

-7.20

LPPPPPPSVA

9.71

-8.96

-6.63
P39743

YSNPLTSPVA

9.40

-5.50

-3.17
P53169

ANSVPIMPTL

11.35

-6.09

-3.76

IMPTLPPRPY

11.66

-7.51

-5.18

VPIMPTLPPR

11.83

-8.65

-6.32

 


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