ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-25.PDB
Scoring matrix: RVS167_FMK-SSH-25_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 17.57
Foldx random average score for Saccharomyces cerevisiae: 16.675

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1680902
Proteins after disorder filtering: 4679
 Total fragments: 134930
Proteins after pattern filtering: 2309
 Total fragments: 20809
Proteins after MINT filtering: 73
 Total fragments: 1170


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

17.57

-1.90

0.00
Best peptides

HYPRLPYFF

0.00

-6.84

-4.94
         
Interactors      
P38140

IQPDLPPRK

5.48

-9.24

-7.34

NIPPHPYPS

8.33

-6.48

-4.58

PMNIQPDLP

8.73

-8.81

-6.91
Q06604

EKPLLPTRP

4.96

-9.57

-7.67

SPPPLPTRR

5.80

-9.03

-7.13

LLPTRPNKA

6.50

-8.44

-6.54
Q12365

IVPREPLRN

5.03

-8.40

-6.50

QIPFIPPQE

8.43

-7.90

-6.00

VKDIPGKFP

10.44

-5.95

-4.05
P40072

PPTTKPGTN

9.87

-6.32

-4.42

NTPSASPML

12.07

-5.40

-3.50

ANTPSASPM

12.15

-5.23

-3.33
P40956

STPPLPRRR

4.87

-9.05

-7.15

ATTSTPPLP

8.93

-6.87

-4.97

NPKNVPFPF

9.60

-6.25

-4.35
Q06833

PVPRRPSQP

5.85

-7.62

-5.72

NRRPVPRRP

6.59

-9.47

-7.57

RRPSQPLNT

7.64

-7.35

-5.45
P40032

ILPNVPHSD

8.81

-7.64

-5.74

FPSILPNVP

9.87

-5.96

-4.06

LRLFPSILP

11.59

-5.05

-3.15
P32628

EPPIAPESA

11.15

-5.62

-3.72

PIAPESATT

15.49

-2.04

-0.14

PPIAPESAT

16.59

-3.32

-1.42
Q12242

KPCDVPNNG

12.05

-5.60

-3.70

TKPCDVPNN

14.49

-4.01

-2.11

GTKPCDVPN

14.96

-3.95

-2.05
P38266

AVPILPPRN

4.34

-9.26

-7.36

SFPPPPLKP

5.34

-9.58

-7.68

LPPPKPFRH

5.75

-7.92

-6.02
P25333

KYPEGAPTS

11.11

-6.90

-5.00

AITPAPTPT

11.74

-5.05

-3.15

TPAPTPTAS

12.15

-4.46

-2.56
P16603

RLPSNPSTP

7.48

-7.79

-5.89

SNPSTPVIM

7.73

-8.25

-6.35

ELPDAPPVV

8.07

-7.12

-5.22
P39692

KLPPSPKQP

4.93

-9.01

-7.11

PSPKQPVIM

8.55

-7.10

-5.20

VMKLPPSPK

9.21

-6.81

-4.91
P38872

GTLPLPNPY

8.24

-8.20

-6.30

LPNLYPHGT

13.08

-5.35

-3.45

INCLPNLYP

13.93

-2.28

-0.38
P17555

GPPPRPKKP

5.88

-9.60

-7.70

PRPKKPSTL

6.56

-8.39

-6.49

PPPPPPAPP

8.25

-7.72

-5.82
Q12344

SSPPLPPRQ

6.49

-7.32

-5.42

SPPLPPRQN

7.55

-8.37

-6.47

TSPKLPPRG

7.56

-8.02

-6.12
P38289

EDPENPSFI

8.92

-8.06

-6.16

DPENPSFIN

12.46

-3.60

-1.70

VPTNDPSGI

13.43

-4.25

-2.35
Q03780

IPPRSPNRN

5.37

-6.94

-5.04

SRPPPPPMD

6.55

-8.50

-6.60

KRSRPPPPP

7.46

-7.97

-6.07
P53316

MMPMFPSFG

6.96

-8.35

-6.45

QVPPVPYII

7.22

-8.23

-6.33

FIPQVPPVP

7.67

-8.10

-6.20
P32190

RRPSTAPAR

8.69

-6.71

-4.81

RPSTAPARE

12.05

-4.77

-2.87

GLRRPSTAP

12.68

-4.84

-2.94
Q12389

DPSQGPAAN

12.27

-4.37

-2.47

LEDPSQGPA

12.31

1.26

3.16

LLEDPSQGP

13.06

-4.13

-2.23
P13186

SIPMSPNYG

8.17

-7.10

-5.20

LPEREPPTY

8.73

-5.87

-3.97

NIPLTPLAT

9.38

-6.58

-4.68
P12630

NPFCLPNSN

9.99

-6.13

-4.23

SSNPFCLPN

13.11

-3.00

-1.10

PFCLPNSNT

14.17

-3.08

-1.18
P39940

DDPRLPSSL

8.07

-7.53

-5.63

TTWDDPRLP

10.01

-6.09

-4.19

PRLPSSLDQ

12.60

-3.62

-1.72
P04051

QDRSLPHFP

8.78

-6.45

-4.55

SLPHFPKNS

8.87

-7.43

-5.53

NPAMLPGSS

12.23

-4.60

-2.70
P43603

TAPTSPSTS

10.39

-4.95

-3.05

GRFTAPTSP

10.69

-5.64

-3.74

FTAPTSPST

14.34

-2.77

-0.87
P15891

AQPPLPSRN

4.17

-9.82

-7.92

AAPPPPPRR

7.37

-8.17

-6.27

APPPPPRRA

7.99

-6.96

-5.06
P07278

STPPLPMHF

4.74

-9.45

-7.55

KTSTPPLPM

10.86

-5.35

-3.45
P06777

LIPNEPDDI

10.21

-6.71

-4.81
P27999

SDPTLPRSD

9.67

-6.87

-4.97

DIGSDPTLP

11.50

-6.93

-5.03

PTLPRSDRE

12.26

-4.65

-2.75
P47029

ILPRDPPSY

6.31

-8.30

-6.40

KHPTPPSLK

6.67

-7.72

-5.82

KGPKLPNLP

7.15

-8.12

-6.22
Q12168

GPPPLPPRA

6.45

-8.64

-6.74

IPPPVPNRP

6.94

-8.84

-6.94

DDPYFPQFR

6.98

-6.63

-4.73
Q04322

TPPTLPPRR

5.88

-8.69

-6.79

TSPPLPPRA

6.85

-7.67

-5.77

SPPLPPRAD

10.18

-6.02

-4.12
P08458

LPKRKPPKL

7.66

-6.49

-4.59

PKRKPPKLQ

10.09

-7.08

-5.18

NLPKRKPPK

11.70

-3.93

-2.03
Q02209

GPESKPNVN

8.78

-6.15

-4.25

YKGPESKPN

11.55

-4.45

-2.55

IYKGPESKP

11.97

-5.78

-3.88
Q12496

IPSNIPKKR

9.79

-7.15

-5.25

NIPKKRPFL

11.37

-6.62

-4.72

SNIPKKRPF

13.43

-6.62

-4.72
P32793

HGPTHPSNM

9.30

-6.15

-4.25

SLGHGPTHP

10.83

-5.81

-3.91

PTHPSNMSN

14.64

-2.23

-0.33
P36006

PIPPPPPPM

7.51

-8.94

-7.04

GQPKDPKFE

7.69

-8.31

-6.41

NIPIPPPPP

7.88

-8.47

-6.57
P32875

RTPSKPDPM

6.51

-8.71

-6.81

KTNRTPSKP

7.97

-8.23

-6.33

PSKPDPMEP

11.73

-4.46

-2.56
Q08412

ELPTQPVRK

6.40

-8.39

-6.49

KWQPLPPEP

7.48

-7.91

-6.01

VPPQLPTRT

7.51

-6.98

-5.08
Q06440

RTPKVEPSK

12.26

-5.03

-3.13

DRTPKVEPS

14.90

-5.83

-3.93
P38750

LPHNLPHNH

10.25

-5.27

-3.37

APASSPAYT

10.72

-4.59

-2.69

TFPHNAPAS

11.36

-5.27

-3.37
P26570

MEPKSPILK

7.68

-6.97

-5.07

STPSKPNLE

8.06

-8.07

-6.17

PDPSTPSKP

8.20

-7.37

-5.47
P31374

KKPGTPVFP

5.48

-8.44

-6.54

FRKTKPPPP

6.33

-8.30

-6.40

ISPERPSFR

6.52

-8.50

-6.60
P38237

NDPFVPPPN

7.80

-8.03

-6.13

PFVPPPNVP

7.85

-7.52

-5.62

QIPSKPENT

8.67

-7.98

-6.08
P34223

MPDNEPKQG

10.39

-5.63

-3.73

PMPDNEPKQ

10.93

-5.03

-3.13

LEVTDPSDP

11.46

-4.78

-2.88
P53118

NPHDLPSHL

9.91

-5.82

-3.92

PHDLPSHLG

11.68

-4.26

-2.36
P32389

NHPFEPNFM

5.04

-8.42

-6.52

MQNNHPFEP

11.18

-4.84

-2.94

FMGSPSQFP

12.07

-3.58

-1.68
P53933

RRPPPPPIP

4.82

-9.41

-7.51

APPPLPNRQ

6.69

-8.26

-6.36

KRVAPPPLP

7.39

-7.69

-5.79
P32790

LPPIKPPRP

5.60

-8.66

-6.76

PPPAMPARP

6.86

-9.20

-7.30

IKPPRPTST

7.75

-6.84

-4.94
P33400

ILPPLPVGI

6.96

-8.56

-6.66

SPQILPPLP

8.30

-7.49

-5.59

SYVQPPNAP

8.43

-6.76

-4.86
P23293

SRPSHPQFP

5.00

-7.37

-5.47

QFPISPSQG

7.29

-7.05

-5.15

NKVPLPLGP

7.73

-7.44

-5.54
Q04439

SKPKEPMFE

6.57

-8.69

-6.79

NIPPPPPPP

7.45

-9.20

-7.30

IPPPPPPPP

7.70

-8.14

-6.24
P33338

ARTPTPTPP

7.33

-8.00

-6.10

TPARTPART

9.57

-4.97

-3.07

TPTPTPPVV

9.79

-5.18

-3.28
Q12446

PLPQLPNRN

4.08

-9.96

-8.06

SLPPLPNQF

4.38

-10.99

-9.09

PLPDPPQHN

5.92

-8.37

-6.47
P22219

SPGETPYLI

10.79

-5.67

-3.77

AVSPGETPY

14.78

-2.62

-0.72

SAVSPGETP

15.65

-3.40

-1.50
P53220

RNKPKPLWP

7.40

-9.22

-7.32
Q12373

KRPLSQPTT

9.93

-1.28

0.62

SKRPLSQPT

12.19

-5.35

-3.45

RPLSQPTTS

12.96

-4.57

-2.67
P41695

ETPVKPSLT

7.65

-7.78

-5.88

LAHETPVKP

10.54

-5.62

-3.72

TPVKPSLTS

15.45

-1.12

0.78
Q00916

PRPPLSYKR

6.57

-7.38

-5.48

SRLFKPRPP

6.58

-7.76

-5.86

FKPRPPLSY

6.79

-7.60

-5.70
P53901

NQPPLPPIP

4.93

-8.99

-7.09

PLPPIPTRD

5.90

-8.74

-6.84

NSPKLPPLP

6.50

-8.26

-6.36
P38990

SVPNLPSAP

7.20

-8.04

-6.14

PSPIRPVLP

7.38

-8.01

-6.11

RNQNLPKIP

8.75

-9.10

-7.20
P47110

TPPRKPSPV

6.82

-6.95

-5.05

SKPNSPKET

8.10

-6.12

-4.22

ATSTPPRKP

10.31

-7.86

-5.96
P10566

STRPIPAIP

8.81

-7.44

-5.54

TRPIPAIPM

9.11

-7.10

-5.20

PIPAIPMDL

9.89

-7.19

-5.29
P25693

NRPIPTIKP

15.37

-5.78

-3.88
Q07821

DSQRPGKKP

13.69

-4.28

-2.38
P25558

RHPKSPVKK

5.53

-6.69

-4.79

ELPNTPRSI

7.85

-7.86

-5.96

SPVKKPMTS

10.80

-5.76

-3.86
P40325

SQPPRPPRP

4.52

-9.81

-7.91

PRPPRPAAN

4.82

-9.38

-7.48

SQPRPPPRP

5.48

-8.10

-6.20
P37370

NRPHMPSVR

5.74

-8.56

-6.66

SQMPKPRPF

6.02

-8.95

-7.05

SAPPIPDIP

6.69

-7.46

-5.56
Q08446

SHSPISPLK

10.67

-4.72

-2.82

NSSHSPISP

12.87

-3.00

-1.10
P39743

SNPLTSPVA

11.98

-4.41

-2.51

NATIPEDNP

15.16

-0.10

1.80
P47129

GPPLLPPRN

5.01

-8.81

-6.91

NRKPNPPPN

6.55

-7.23

-5.33

RKPNPPPNR

7.47

-7.26

-5.36
P53169

IMPTLPPRP

4.12

-9.72

-7.82

SVPIMPTLP

5.91

-9.28

-7.38

MPTLPPRPY

9.62

-6.36

-4.46

 


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