ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-23.PDB
Scoring matrix: RVS167_FMK-SSH-23_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 10.21
Foldx random average score for Saccharomyces cerevisiae: 9.697

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1885481
Proteins after disorder filtering: 4927
 Total fragments: 124580
Proteins after pattern filtering: 2175
 Total fragments: 8750
Proteins after MINT filtering: 70
 Total fragments: 420


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

10.21

-0.57

0.00
Best peptides

MPLMPWF

0.00

-4.81

-4.24
         
Interactors      
P38140

QPDLPPR

7.79

-3.20

-2.63

IPPHPYP

7.91

-2.77

-2.20

IQPDLPP

8.68

-2.04

-1.47
Q06604

GPRMPSR

4.81

-4.51

-3.94

KPLLPTR

5.66

-5.86

-5.29

LPTRPNK

5.68

-4.61

-4.04
Q12365

VPREPLR

4.76

-4.42

-3.85

IVPREPL

6.06

-3.35

-2.78

IPGKFPS

7.84

-2.78

-2.21
P40072

TPSASPM

6.87

-2.38

-1.81

PSASPML

7.97

-1.93

-1.36

PTTKPGT

8.88

-2.35

-1.78
P40956

NPKNVPF

5.98

-2.38

-1.81

WNPKNVP

7.22

-3.43

-2.86

TPPLPRR

7.36

-3.47

-2.90
Q06833

RPSQPLN

5.14

-3.74

-3.17

VPRRPSQ

5.23

-4.12

-3.55

RRPSQPL

6.09

-3.74

-3.17
P40032

LFPSILP

7.16

-3.71

-3.14

ILPNVPH

7.27

-2.13

-1.56

VPHSDPS

8.77

-1.72

-1.15
P32628

PPIAPES

7.88

-3.80

-3.23
Q12242

KPCDVPN

8.41

-2.27

-1.70

TKPCDVP

8.66

-2.61

-2.04
P38266

YPIEPSL

4.28

-4.32

-3.75

KDPKSFP

5.25

-4.19

-3.62

PPLKPGQ

5.53

-4.79

-4.22
P25333

KYPEGAP

7.32

-3.00

-2.43

ITPAPTP

7.97

-3.10

-2.53

YPEGAPT

8.14

-1.15

-0.58
P16603

LPDAPPV

5.90

-3.29

-2.72

LPSNPST

6.63

-2.98

-2.41

RLPSNPS

8.06

-2.89

-2.32
P39692

LPPSPKQ

6.72

-3.07

-2.50

SPKQPVI

6.85

-3.14

-2.57

PSPKQPV

8.22

-2.32

-1.75
P38872

CLPNLYP

7.05

-2.72

-2.15

LPNLYPH

7.74

-3.65

-3.08

TLPLPNP

9.11

-2.90

-2.33
P17555

RPKKPST

4.50

-5.76

-5.19

PPPRPKK

6.52

-3.02

-2.45

AAPAPPP

7.96

-2.73

-2.16
Q12344

TSPKLPP

6.99

-3.27

-2.70

SPKLPPR

7.68

-3.85

-3.28

SPPLPPR

8.54

-2.52

-1.95
P38289

DPENPSF

8.04

-1.26

-0.69

VPTNDPS

9.15

-0.86

-0.29

EDPENPS

9.21

-1.49

-0.92
Q03780

PPRSPNR

6.95

-1.75

-1.18

IPPRSPN

7.09

-3.17

-2.60

SAPDIPP

9.50

-1.26

-0.69
P53316

MMPMFPS

5.77

-4.43

-3.86

MPMFPSF

6.78

-3.88

-3.31

FIPQVPP

7.46

-3.11

-2.54
P32190

RRPSTAP

7.11

-3.93

-3.36

PSTAPAR

8.90

-2.70

-2.13
Q12389

DPSQGPA

8.46

-1.55

-0.98

PSQGPAA

9.29

-0.47

0.10

EDPSQGP

9.33

-1.82

-1.25
P13186

LPEREPP

5.83

-4.28

-3.71

IPMSPNY

5.98

-4.01

-3.44

PEREPPT

6.98

-3.07

-2.50
P12630

NPFCLPN

7.98

-2.33

-1.76
P39940

DPRLPSS

8.49

-3.16

-2.59

DDPRLPS

8.91

-2.00

-1.43
P04051

NPAMLPG

7.54

-2.75

-2.18

VNPAMLP

8.01

-3.43

-2.86

PAMLPGS

8.83

-4.72

-4.15
P43603

APTSPST

9.48

-1.48

-0.91
P15891

TPEKKPK

6.53

-2.96

-2.39

PEKKPKE

7.03

-4.00

-3.43

TPSKSPA

7.04

-2.38

-1.81
P07278

TPPLPMH

7.31

-3.56

-2.99
P06777

LIPNEPD

7.83

-2.51

-1.94

IPNEPDD

8.17

-1.39

-0.82
P27999

DPTLPRS

9.51

-2.54

-1.97
P47029

LPRDPPS

6.23

-3.63

-3.06

KGPKLPN

6.70

-3.27

-2.70

ILPRDPP

6.75

-3.56

-2.99
Q12168

PVPKPNI

7.62

-2.45

-1.88

VPNRPGG

8.37

-2.17

-1.60

PPPLPPR

8.70

-3.41

-2.84
Q04322

PLDRPQL

6.60

-2.73

-2.16

TPSKSPT

6.78

-2.49

-1.92

APLDRPQ

7.05

-2.74

-2.17
P08458

LPKRKPP

4.68

-5.73

-5.16

PKRKPPK

4.80

-3.22

-2.65

NLPKRKP

6.34

-3.94

-3.37
Q02209

KGPESKP

6.66

-3.23

-2.66

PESKPNV

7.85

-1.82

-1.25
Q12496

IPKKRPF

4.03

-4.52

-3.95

PKKRPFL

5.26

-5.36

-4.79

NIPKKRP

6.12

-3.18

-2.61
P36006

PPMGQPK

6.69

-4.54

-3.97

QPKDPKF

6.74

-2.62

-2.05

KPKNPGG

6.91

-3.56

-2.99
P32875

TPSKPDP

6.15

-2.88

-2.31

PDPMEPE

7.59

-2.42

-1.85

RTPSKPD

7.91

-2.67

-2.10
Q08412

LPPEPLD

6.47

-3.11

-2.54

LPTQPVR

6.54

-4.22

-3.65

VPPQLPT

7.64

-2.36

-1.79
Q06440

RTPKVEP

5.87

-4.62

-4.05

PKVEPSK

7.91

-4.02

-3.45
P38750

LPHNLPH

5.85

-2.85

-2.28

PPILPRT

7.40

-4.61

-4.04

FPHNAPA

7.95

-1.38

-0.81
P26570

MEPKSPI

5.08

-4.60

-4.03

TPSKPNL

5.61

-2.71

-2.14

EPKSPIL

6.24

-3.48

-2.91
P31374

SPERPSF

6.92

-2.61

-2.04

QPRLPST

7.69

-2.94

-2.37

ISPERPS

7.90

-1.78

-1.21
P38237

IPSKPEN

6.24

-2.75

-2.18

PPPNVPK

7.99

-2.78

-2.21

QIPSKPE

9.63

-1.28

-0.71
P34223

MPDNEPK

4.73

-3.81

-3.24

SPAEVPK

7.92

-1.73

-1.16

PDNEPKQ

8.60

-1.98

-1.41
P53118

PHDLPSH

8.67

-2.33

-1.76

NPHDLPS

9.06

0.19

0.76
P32389

HPFEPNF

6.44

-2.11

-1.54

SPSQFPA

8.09

-1.51

-0.94

GSPSQFP

8.78

-2.55

-1.98
P53933

LPMELPH

3.98

-4.92

-4.35

DLPMELP

6.75

-3.82

-3.25

YPGNPTS

8.73

-1.43

-0.86
P32790

PPIKPPR

5.34

-4.81

-4.24

APLDPFK

5.64

-3.24

-2.67

MPARPTA

6.68

-3.88

-3.31
P33400

TSPQILP

7.40

-3.13

-2.56

PQILPPL

7.62

-5.35

-4.78

PPNAPSY

8.83

-1.74

-1.17
P23293

IPRGPKK

4.92

-3.02

-2.45

LPLGPQS

5.92

-4.16

-3.59

RPSHPQF

6.76

-2.05

-1.48
Q04439

KPKEPMF

3.48

-4.93

-4.36

KKPAPPP

6.20

-3.77

-3.20

SKPKEPM

6.67

-2.79

-2.22
P33338

RTPARTP

6.97

-4.33

-3.76

TPARTPT

8.08

-2.33

-1.76

TPARTPA

8.34

-2.26

-1.69
Q12446

RLPAPPP

5.79

-4.41

-3.84

RGPAPPP

5.96

-4.26

-3.69

LPQLPNR

6.50

-3.98

-3.41
P22219

SPGETPY

9.02

-1.42

-0.85

VSPGETP

9.05

-1.60

-1.03
Q12373

RPLSQPT

5.15

-4.16

-3.59

KRPLSQP

7.96

-3.61

-3.04

PLSQPTT

8.62

-1.47

-0.90
P41695

TPVKPSL

6.10

-3.48

-2.91
Q00916

FKPRPPL

5.75

-3.42

-2.85

RPTDYPY

7.69

-2.84

-2.27
P53901

NSPKLPP

6.78

-3.25

-2.68

SPKLPPL

7.22

-4.23

-3.66

QPPLPPI

8.22

-2.47

-1.90
P38990

SPIRPVL

5.79

-4.79

-4.22

LPSAPSS

6.85

-3.00

-2.43

NLPKIPN

7.53

-2.58

-2.01
P47110

PPRKPSP

5.34

-4.15

-3.58

KPNSPKE

7.58

-2.68

-2.11

TPPRKPS

7.80

-2.62

-2.05
P10566

AIPMDLP

7.04

-3.71

-3.14

IPMDLPD

7.06

-2.32

-1.75

PIPAIPM

8.45

-2.34

-1.77
Q07821

QRPGKKP

8.42

-1.99

-1.42
P25558

RHPKSPV

5.68

-4.28

-3.71

PVKKPMT

6.46

-4.08

-3.51

SPVKKPM

6.75

-3.47

-2.90
P40325

RPHQRPS

5.72

-2.93

-2.36

RPQQNPS

5.82

-3.19

-2.62

RPPRPAA

6.00

-3.93

-3.36
P37370

IPLAPLP

4.37

-5.55

-4.98

RPHMPSV

4.44

-4.16

-3.59

PTLAPPL

5.84

-4.70

-4.13
Q08446

SPISPLK

6.33

-3.69

-3.12
P39743

TIPEDNP

8.63

-2.31

-1.74
P47129

RKPNPPP

5.81

-3.77

-3.20

PNRKPNP

6.14

-4.38

-3.81

PPLLPPR

6.69

-6.32

-5.75
P53169

VPIMPTL

4.47

-5.09

-4.52

MPTLPPR

6.64

-4.48

-3.91

YSPAQPS

7.96

-2.24

-1.67

 


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