ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-18.PDB
Scoring matrix: RVS167_FMK-SSH-18_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAAA
Foldx wt ligand score: 17.94
Foldx random average score for Saccharomyces cerevisiae: 14.961

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1372309
Proteins after disorder filtering: 4431
 Total fragments: 70055
Proteins after pattern filtering: 2177
 Total fragments: 12414
Proteins after MINT filtering: 71
 Total fragments: 680


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAAA

17.94

-2.30

0.00
Best peptides

FPFIRPIMFW

0.00

-1.85

0.45
         
Interactors      
P38140

IQPDLPPRKI

11.36

-2.39

-0.09

QPDLPPRKIM

11.48

-6.04

-3.74

PHPYPSSNQN

13.10

-0.44

1.86
Q06604

LLPTRPNKAE

7.72

-5.15

-2.85

YSNIPSSKPA

11.09

-5.36

-3.06

SFEKGPRMPS

11.51

-1.97

0.33
Q12365

IPFIPPQEDD

9.98

-5.84

-3.54

VKDIPGKFPS

11.34

-5.34

-3.04

IVPREPLRNE

14.28

-3.68

-1.38
P40072

PPTTKPGTNS

12.52

-5.73

-3.43

APPTTKPGTN

14.01

-4.24

-1.94

LDAAPPTTKP

14.28

-4.15

-1.85
P40956

RFWNPKNVPF

9.84

-1.76

0.54

NPKNVPFPFD

10.82

-5.11

-2.81

WNPKNVPFPF

12.34

-4.55

-2.25
Q06833

RPVPRRPSQP

11.64

-5.22

-2.92

PVPRRPSQPL

11.66

-4.99

-2.69

FPVPPSASNM

12.00

-5.04

-2.74
P40032

FPSILPNVPH

6.64

-7.89

-5.59

LRLFPSILPN

10.83

-3.98

-1.68

LPNVPHSDPS

12.84

-5.20

-2.90
P32628

EPPIAPESAT

9.96

-6.43

-4.13
Q12242

KPCDVPNNGD

12.90

-3.52

-1.22
P38266

LKKKPPVVPK

9.10

-4.94

-2.64

TPPRPPPSRS

10.02

-4.93

-2.63

PPPLKPGQKT

10.77

-7.07

-4.77
P25333

YPEGAPTSGA

14.61

-3.93

-1.63
P16603

RLPSNPSTPV

11.76

-4.36

-2.06

LPSNPSTPVI

12.30

-3.51

-1.21

NFRLPSNPST

12.68

-3.56

-1.26
P39692

PSPKQPVIMS

11.49

-4.02

-1.72

VMKLPPSPKQ

11.83

-5.42

-3.12

KLPPSPKQPV

13.48

-4.23

-1.93
P38872

LPNLYPHGTL

9.86

-4.10

-1.80

HGTLPLPNPY

13.46

-3.96

-1.66

CLPNLYPHGT

13.94

-1.89

0.41
P17555

RPKKPSTLKT

8.36

-6.74

-4.44

GPPPRPKKPS

11.75

-5.20

-2.90

KSGPPPRPKK

13.49

-3.61

-1.31
Q12344

SPKLPPRGKQ

10.54

-5.75

-3.45

SPPLPPRQNV

11.38

-6.09

-3.79

PLPPRQNVAT

13.16

-4.13

-1.83
P38289

DPENPSFINY

11.91

-4.61

-2.31

VPTNDPSGIL

12.43

-4.60

-2.30

HMYDVPTNDP

14.40

-1.86

0.44
Q03780

APDIPPRSPN

9.70

-6.48

-4.18

RPPPPPMDMK

9.92

-6.87

-4.57

IPPRSPNRNA

10.25

-5.75

-3.45
P53316

IPQVPPVPYI

9.88

-5.44

-3.14

MPMFPSFGFI

10.14

-6.48

-4.18

MMPMFPSFGF

10.28

-4.60

-2.30
P32190

RPSTAPARET

10.34

-4.76

-2.46

RRPSTAPARE

13.42

-3.38

-1.08

SGLRRPSTAP

13.75

-2.63

-0.33
Q12389

LLEDPSQGPA

12.90

-5.13

-2.83

DPSQGPAANG

13.86

-4.25

-1.95
P13186

RPPIPAALPP

11.07

-6.41

-4.11

PAALPPSDMT

12.82

-5.19

-2.89

NSSIPMSPNY

13.18

-4.52

-2.22
P12630

NPFCLPNSNT

11.43

-5.20

-2.90
P39940

WDDPRLPSSL

12.48

-3.53

-1.23

DPRLPSSLDQ

12.76

-4.25

-1.95
P04051

LPHFPKNSKT

10.57

-5.23

-2.93

NPAMLPGSSN

11.46

-5.62

-3.32

FQDRSLPHFP

12.40

-5.38

-3.08
P43603

GRFTAPTSPS

13.64

-2.64

-0.34

TAPTSPSTSS

14.15

-2.42

-0.12
P15891

RRATPEKKPK

12.07

-3.47

-1.17

APPPPPRRAT

13.10

-5.00

-2.70

QPPLPSRNVA

13.11

-6.00

-3.70
P07278

KTSTPPLPMH

13.87

-3.99

-1.69

TSTPPLPMHF

14.80

-1.69

0.61
P06777

LIPNEPDDIE

14.63

-1.38

0.92

IPNEPDDIET

14.93

-3.88

-1.58
P27999

SDPTLPRSDR

13.28

-3.67

-1.37

DPTLPRSDRE

13.50

-5.65

-3.35
P47029

LPRDPPSYKD

9.30

-4.76

-2.46

ILPRDPPSYK

9.44

-4.37

-2.07

KHPTPPSLKA

9.53

-1.89

0.41
Q12168

PPPLPPRANV

11.74

-6.65

-4.35

HPVPKPNIDD

11.86

-4.07

-1.77

PVPNRPGGTT

12.31

-3.44

-1.14
Q04322

TPPTLPPRRI

10.41

-5.66

-3.36

TPSKSPTSAV

11.79

-5.20

-2.90
P08458

NLPKRKPPKL

9.36

-5.76

-3.46

PKRKPPKLQG

11.04

-3.15

-0.85

TPITNPSSSS

12.64

-3.95

-1.65
Q02209

GPESKPNVNF

12.04

-4.43

-2.13

PESKPNVNFM

12.52

-3.08

-0.78
Q12496

IPSNIPKKRP

12.32

-3.99

-1.69

PSNIPKKRPF

13.07

-5.01

-2.71
P32793

HGPTHPSNMS

11.27

-3.86

-1.56

GPTHPSNMSN

12.76

-3.49

-1.19

SLGHGPTHPS

14.27

-2.78

-0.48
P36006

KPKNPGGLSG

11.43

-4.48

-2.18

KSNKKPKNPG

12.53

-4.57

-2.27

IPPPPPPMGQ

12.83

-4.28

-1.98
P32875

VKTNRTPSKP

11.97

-3.96

-1.66

TPSKPDPMEP

13.76

-4.55

-2.25

RTPSKPDPME

14.36

-4.20

-1.90
Q08412

ELPTQPVRKN

10.73

-4.38

-2.08

VPPQLPTRTK

11.94

-4.34

-2.04

GKNSRPQQPE

12.24

-2.79

-0.49
Q06440

KDRTPKVEPS

13.05

-4.84

-2.54

KKDRTPKVEP

13.37

-3.26

-0.96
P38750

HLGLPHNLPH

10.85

-6.27

-3.97

PPGVFPVRGM

12.05

-4.73

-2.43

FPHNAPASSP

12.06

-4.56

-2.26
P26570

MEPKSPILKT

9.20

-2.96

-0.66

DPTDSPNEWE

11.02

-4.92

-2.62

TPLNSPGLSK

11.28

-3.99

-1.69
P31374

FPNLDPTHSQ

10.27

-6.15

-3.85

FRKTKPPPPL

10.63

-5.20

-2.90

ISPERPSFRQ

10.67

-1.73

0.57
P38237

NFQIPSKPEN

11.46

-3.91

-1.61

IPSKPENTVN

13.18

-5.56

-3.26

PFVPPPNVPK

13.33

-2.61

-0.31
P34223

MPDNEPKQGD

12.18

-3.96

-1.66

LEVTDPSDPN

13.06

-1.77

0.53

EQPMPDNEPK

13.21

-4.05

-1.75
P53118

PHDLPSHLGS

13.60

-0.81

1.49
P32389

NHPFEPNFMG

10.35

-2.67

-0.37

MQNNHPFEPN

12.02

-3.66

-1.36

FMGSPSQFPA

12.47

-4.56

-2.26
P53933

PPPIPSTQKP

11.27

-6.75

-4.45

RPPPPPIPST

11.48

-4.80

-2.50

RRPPPPPIPS

11.79

-4.27

-1.97
P32790

LPPIKPPRPT

7.67

-7.32

-5.02

IKPPRPTSTT

11.69

-3.16

-0.86

PPIKPPRPTS

12.22

-4.21

-1.91
P33400

SPQILPPLPV

9.96

-6.17

-3.87

QPPNAPSYQS

10.00

-4.72

-2.42

SYVQPPNAPS

14.31

-2.71

-0.41
P23293

HQGSRPSHPQ

9.98

-2.87

-0.57

FPISPSQGQH

10.55

-4.68

-2.38

QFPISPSQGQ

11.19

-1.09

1.21
Q04439

KPAPPPPGMQ

10.95

-6.84

-4.54

SKPKEPMFEA

12.40

-3.43

-1.13

RHSKKPAPPP

12.73

-2.50

-0.20
P33338

TPARTPARTP

14.23

-4.35

-2.05

TPARTPTPTP

14.89

-3.60

-1.30
Q12446

RPVPPPPPMR

10.12

-7.07

-4.77

FPFPVPQQQF

10.51

-4.47

-2.17

IPEIPSTQSA

10.78

-5.66

-3.36
P22219

NPDFPYNNSN

13.26

-3.58

-1.28
P53220

TRNKPKPLWP

13.06

-3.75

-1.45
Q12373

RPLSQPTTSI

11.58

-3.82

-1.52

KRPLSQPTTS

13.04

-3.55

-1.25
P41695

TPVKPSLTSN

12.56

-4.27

-1.97

LAHETPVKPS

13.79

-3.75

-1.45
Q00916

FKPRPPLSYK

7.87

-5.77

-3.47

RPTDYPYAKR

9.23

-6.18

-3.88

LFKPRPPLSY

9.32

-1.05

1.25
P53901

DPIILPPTFS

8.62

-7.17

-4.87

MRPIPPLPTE

10.09

-5.02

-2.72

LPPIPTRDDM

10.24

-5.38

-3.08
P38990

RNQNLPKIPN

11.81

-4.13

-1.83

LPSAPSSTRL

12.08

-4.21

-1.91

NLPSAPSSTR

12.88

-2.36

-0.06
P47110

SKPNSPKETD

12.91

-0.56

1.74

KPNSPKETDS

14.19

-4.47

-2.17

NGGSKPNSPK

14.28

-2.55

-0.25
P10566

TRPIPAIPMD

10.81

-3.77

-1.47

IPAIPMDLPD

11.13

-6.84

-4.54

RPIPAIPMDL

13.57

-4.38

-2.08
Q07821

PDSQRPGKKP

12.18

-4.91

-2.61
P25558

RHPKSPVKKP

9.67

-2.78

-0.48

SPVKKPMTSE

12.10

-4.34

-2.04

LPNTPRSINV

12.14

-5.01

-2.71
P40325

LPWTYPPRFY

8.13

-6.23

-3.93

RPHQRPSTMP

8.30

-6.54

-4.24

RPQQNPSLPW

9.00

-5.96

-3.66
P37370

VPQNRPHMPS

7.30

-3.85

-1.55

SPSINPPKQS

9.18

-6.39

-4.09

RPHMPSVRPA

9.22

-8.72

-6.42
Q08446

NSSHSPISPL

13.09

-2.69

-0.39
P47129

RKPNPPPNRS

8.72

-2.81

-0.51

PPLLPPRNTM

11.28

-4.70

-2.40

LPNRKPNPPP

11.89

-4.20

-1.90
P53169

IMPTLPPRPY

11.44

-5.47

-3.17

VPIMPTLPPR

13.51

-6.93

-4.63

TANSVPIMPT

13.85

-2.83

-0.53

 


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