ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-17.PDB
Scoring matrix: RVS167_FMK-SSH-17_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 15.06
Foldx random average score for Saccharomyces cerevisiae: 14.573

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1372086
Proteins after disorder filtering: 4525
 Total fragments: 64704
Proteins after pattern filtering: 2096
 Total fragments: 8763
Proteins after MINT filtering: 67
 Total fragments: 440


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

15.06

-2.03

0.00
Best peptides

RPFMRGFMR

0.00

-6.48

-4.45
         
Interactors      
P38140

NIQPDLPPR

10.69

-4.33

-2.30

PDLPPRKIM

10.73

-4.39

-2.36

ANIPPHPYP

13.00

-5.39

-3.36
Q06604

GPRMPSRGR

7.67

-6.46

-4.43

EKGPRMPSR

9.92

-5.14

-3.11

EEKPLLPTR

10.47

-4.08

-2.05
Q12365

VPREPLRNE

13.24

-5.17

-3.14

KDIPGKFPS

13.69

-2.59

-0.56
P40072

NTPSASPML

12.27

-0.97

1.06

PTTKPGTNS

12.60

-3.35

-1.32

APPTTKPGT

14.42

-3.28

-1.25
P40956

TSTPPLPRR

9.55

-5.54

-3.51

PPLPRRRAT

11.81

-6.42

-4.39

FWNPKNVPF

12.65

-5.27

-3.24
Q06833

RPVPRRPSQ

8.82

-8.45

-6.42

FPVPPSASN

11.28

-5.93

-3.90

RPSQPLNTL

11.35

-6.43

-4.40
P40032

LFPSILPNV

12.27

-3.26

-1.23

LPNVPHSDP

12.67

-4.20

-2.17

LRLFPSILP

13.56

-7.36

-5.33
P32628

PPIAPESAT

14.35

-4.47

-2.44
P22219

NPDFPYNNS

13.87

-4.31

-2.28
P38266

FLPPPKPFR

7.25

-6.08

-4.05

FQPPPKPFR

7.56

-6.92

-4.89

IMPPPKPFR

9.07

-5.90

-3.87
P25333

DKYPEGAPT

13.93

-1.72

0.31

ITPAPTPTA

14.46

-3.70

-1.67
P16603

FPNPELPDA

12.72

-4.66

-2.63

NPSTPVIMI

13.12

-2.92

-0.89

FRLPSNPST

13.21

-4.22

-2.19
P39692

MKLPPSPKQ

11.03

-5.01

-2.98

PPSPKQPVI

11.32

-6.93

-4.90

LPPSPKQPV

12.42

-4.87

-2.84
P38872

NCLPNLYPH

13.59

-3.21

-1.18
P17555

RPKKPSTLK

8.95

-7.75

-5.72

PPAPPASVF

12.16

-5.47

-3.44

PPRPKKPST

12.24

-6.55

-4.52
Q12344

STSPKLPPR

10.82

-5.64

-3.61

TSSPPLPPR

10.93

-6.83

-4.80

PPLPPRQNV

12.17

-5.87

-3.84
P38289

DPENPSFIN

13.76

-4.02

-1.99

YDVPTNDPS

14.10

-3.16

-1.13
Q03780

DIPPRSPNR

8.59

-7.12

-5.09

PPPPPMDMK

11.71

-5.51

-3.48

TSAPDIPPR

12.44

-4.37

-2.34
P53316

MPMFPSFGF

10.47

-6.56

-4.53

WMMPMFPSF

12.15

-6.11

-4.08

YIIPPQNPA

12.31

-4.61

-2.58
P32190

RRPSTAPAR

9.19

-3.38

-1.35

GLRRPSTAP

14.34

-4.04

-2.01
Q12389

EDPSQGPAA

11.56

-1.47

0.56
P13186

KAPSYVPNR

12.15

-4.36

-2.33

NNIPLTPLA

12.54

-4.27

-2.24

SSIPMSPNY

13.08

-3.89

-1.86
P39940

WDDPRLPSS

11.97

-6.05

-4.02
P04051

RSLPHFPKN

11.11

-4.42

-2.39

LPHFPKNSK

11.59

-6.47

-4.44

PHFPKNSKT

14.23

-3.30

-1.27
P43603

FTAPTSPST

13.05

-4.37

-2.34

RFTAPTSPS

13.83

-3.26

-1.23

APTSPSTSS

14.12

-3.56

-1.53
P15891

AAQPPLPSR

10.98

-4.79

-2.76

FTPSKSPAP

12.10

-5.01

-2.98

PPPPPRRAT

12.59

-6.36

-4.33
P07278

TSTPPLPMH

12.29

-4.60

-2.57
P06777

IPNEPDDIE

13.12

-4.05

-2.02
P27999

IGSDPTLPR

13.04

-2.47

-0.44

PTLPRSDRE

13.47

-5.04

-3.01

DPTLPRSDR

14.57

-6.00

-3.97
P47029

HPTPPSLKA

12.20

-5.76

-3.73

NLSPLGAPG

12.92

-2.43

-0.40

PITSPMSNM

12.93

-4.44

-2.41
Q12168

RGPPPLPPR

8.96

-6.21

-4.18

VPNRPGGTT

11.73

-5.45

-3.42

NDDPYFPQF

11.93

-3.80

-1.77
P08458

NLPKRKPPK

11.49

-6.74

-4.71

TNLPKRKPP

14.09

-5.25

-3.22

QTVTPITNP

14.54

-3.32

-1.29
Q02209

PESKPNVNF

13.29

-3.89

-1.86

YKGPESKPN

13.92

-2.52

-0.49

KGPESKPNV

14.44

-2.29

-0.26
Q12496

NIPKKRPFL

10.26

-5.69

-3.66

EIPSNIPKK

12.40

-2.19

-0.16

SNIPKKRPF

13.62

-3.81

-1.78
P36006

PPPPMGQPK

11.25

-4.99

-2.96

MGQPKDPKF

11.49

-6.10

-4.07

KPKNPGGLS

11.81

-5.82

-3.79
P32875

TPSKPDPME

11.17

-5.21

-3.18
Q08412

IELPTQPVR

9.59

-4.06

-2.03

DVPPQLPTR

10.44

-4.20

-2.17

QPLPPEPLD

11.68

-6.93

-4.90
Q06440

RTPKVEPSK

11.24

-3.98

-1.95

KDRTPKVEP

13.66

-1.67

0.36
P38750

SPPGVFPVR

10.97

-4.43

-2.40

LRSPPGVFP

11.07

-6.45

-4.42

LGLPHNLPH

13.42

-4.39

-2.36
P26570

PLNSPGLSK

12.15

-2.77

-0.74

TPSKPNLEV

12.89

-4.60

-2.57

EPKSPILKT

13.08

-3.98

-1.95
P31374

SPERPSFRQ

10.92

-4.97

-2.94

FEQPRLPST

11.52

-5.27

-3.24

KPPPPLDFE

11.93

-5.65

-3.62
P38237

FVPPPNVPK

11.41

-5.08

-3.05

VPPPNVPKK

13.44

-4.85

-2.82

IPSKPENTV

13.48

-4.58

-2.55
P34223

QPMPDNEPK

13.91

-4.62

-2.59

EQPMPDNEP

14.16

-3.59

-1.56
P32389

HPFEPNFMG

11.37

-6.50

-4.47

NNHPFEPNF

11.54

-4.19

-2.16

FMGSPSQFP

13.72

-3.30

-1.27
P53933

VAPPPLPNR

10.33

-5.69

-3.66

PPPPPIPST

13.09

-5.84

-3.81

NDLPMELPH

13.19

-2.65

-0.62
P32790

GPPPAMPAR

10.46

-5.68

-3.65

APAPLDPFK

11.43

-5.13

-3.10

KPPRPTSTT

12.20

-5.59

-3.56
P33400

QILPPLPVG

12.13

-4.88

-2.85

YVQPPNAPS

12.77

-5.09

-3.06

VQPPNAPSY

13.51

-4.41

-2.38
P23293

PAAPAGVNR

10.50

-2.61

-0.58

GAIPRGPKK

10.55

-4.11

-2.08

VPLPLGPQS

10.59

-5.11

-3.08
Q04439

APPPPGMQN

10.36

-5.00

-2.97

RPSPPTAAT

10.73

-6.49

-4.46

KPKEPMFEA

11.64

-3.61

-1.58
P33338

VTPARTPAR

9.88

-6.72

-4.69

RTPTPTPPV

12.30

-4.77

-2.74

RTPARTPTP

12.55

-5.97

-3.94
Q12446

RPLPQLPNR

6.05

-9.26

-7.23

PPPPPRASR

9.40

-7.19

-5.16

PPPRRGPAP

10.30

-8.05

-6.02
Q04322

STPPTLPPR

12.08

-3.59

-1.56

NDQAPLDRP

14.18

-4.15

-2.12
Q12373

PLSQPTTSI

14.03

-2.65

-0.62
P41695

HETPVKPSL

13.35

-5.01

-2.98

TPVKPSLTS

13.36

-4.97

-2.94
Q00916

RLFKPRPPL

10.31

-6.76

-4.73

KPRPPLSYK

10.39

-6.77

-4.74

PRPPLSYKR

10.56

-4.19

-2.16
P53901

PPLPPIPTR

9.67

-5.56

-3.53

RPIPPLPTE

10.86

-6.48

-4.45

YNQPPLPPI

11.65

-6.13

-4.10
P38990

LPSAPSSTR

9.50

-6.38

-4.35

QPSPIRPVL

10.45

-6.10

-4.07

QNLPKIPNS

12.83

-4.63

-2.60
P47110

KPNSPKETD

13.63

-4.12

-2.09

STPPRKPSP

13.74

-6.42

-4.39

GSKPNSPKE

14.19

-2.62

-0.59
P10566

RPIPAIPMD

10.66

-4.97

-2.94

AIPMDLPDY

12.69

-3.69

-1.66
Q07821

DSQRPGKKP

12.71

-4.24

-2.21
P25558

KSPVKKPMT

11.91

-3.48

-1.45

LPNTPRSIN

11.93

-5.46

-3.43

EELPNTPRS

13.38

-2.61

-0.58
P40325

LYVQPGDPR

8.05

-3.61

-1.58

RPPRPAANL

9.69

-7.40

-5.37

QSQPPRPPR

9.99

-6.59

-4.56
P37370

RPHMPSVRP

8.84

-7.68

-5.65

RPSPISPSI

9.61

-6.03

-4.00

KVPQNRPHM

9.64

-5.93

-3.90
Q08446

SHSPISPLK

13.33

-4.48

-2.45
P39743

YSNPLTSPV

13.28

-4.38

-2.35
P47129

SGPPLLPPR

11.72

-4.50

-2.47

PLLPPRNTM

13.10

-4.88

-2.85

NTLPNRKPN

13.18

-2.95

-0.92
P53169

PIMPTLPPR

12.05

-4.27

-2.24

VPIMPTLPP

12.97

-6.26

-4.23

SPAQPSASL

13.07

-4.44

-2.41

 


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