ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-15.PDB
Scoring matrix: RVS167_FMK-SSH-15_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAA
Foldx wt ligand score: 18.86
Foldx random average score for Saccharomyces cerevisiae: 14.584

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1297667
Proteins after disorder filtering: 3949
 Total fragments: 33283
Proteins after pattern filtering: 1774
 Total fragments: 5809
Proteins after MINT filtering: 64
 Total fragments: 347


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAA

18.86

-1.22

0.00
Best peptides

RWFIIFKRM

0.00

-7.19

-5.97
         
Interactors      
P38140

IQPDLPPRK

12.18

-2.77

-1.55

QPDLPPRKI

12.30

-6.36

-5.14

PDLPPRKIM

12.71

-4.67

-3.45
Q06604

PPSPPAKRI

11.10

-5.86

-4.64

PPPLPTRRD

12.24

-4.96

-3.74

KPAPPVSRS

12.58

-4.74

-3.52
Q12365

IVPREPLRN

12.11

-3.76

-2.54

IPGKFPSPL

12.86

-6.00

-4.78

VPREPLRNE

13.71

-4.64

-3.42
P40072

APPTTKPGT

13.89

-4.78

-3.56
P40956

TPPLPRRRA

10.20

-5.17

-3.95

RFWNPKNVP

12.64

-4.33

-3.11

TSTPPLPRR

13.06

-3.81

-2.59
Q06833

RPSQPLNTL

8.52

-8.08

-6.86

RPVPRRPSQ

10.79

-5.99

-4.77

RRPVPRRPS

11.56

-5.49

-4.27
P40032

LFPSILPNV

11.98

-3.43

-2.21

FPSILPNVP

12.88

-8.00

-6.78

RLFPSILPN

13.13

-3.85

-2.63
P32628

EPPIAPESA

13.86

-5.39

-4.17
P22219

SPGETPYLI

13.43

-4.32

-3.10

NPDFPYNNS

13.44

-3.64

-2.42
P38266

PPPKPFRRS

10.05

-6.87

-5.65

KPPVVPKKK

10.33

-6.74

-5.52

GQPPVPVRM

10.69

-4.83

-3.61
P15891

APPPPPRRA

12.30

-5.32

-4.10

RATPEKKPK

12.40

-3.86

-2.64

QPPLPSRNV

13.39

-5.08

-3.86
P53169

MPTLPPRPY

12.16

-5.90

-4.68

NSVPIMPTL

12.73

-3.32

-2.10

IMPTLPPRP

13.27

-4.14

-2.92
P39692

PSPKQPVIM

13.10

-4.48

-3.26

LPPSPKQPV

13.33

-4.95

-3.73

PPSPKQPVI

13.45

-5.42

-4.20
P38872

LPNLYPHGT

14.14

-4.90

-3.68
P17555

RPKKPSTLK

10.97

-7.84

-6.62

PRPKKPSTL

13.58

-5.47

-4.25

PPPRPKKPS

14.36

-5.11

-3.89
Q12344

SSPPLPPRQ

13.08

-2.10

-0.88

TSPKLPPRG

13.20

-3.28

-2.06

PPLPPRQNV

13.99

-5.89

-4.67
P38289

VPTNDPSGI

14.10

-4.91

-3.69

EDPENPSFI

14.52

-2.51

-1.29
Q03780

RPPPPPMDM

9.94

-10.03

-8.81

IPPRSPNRN

11.24

-5.12

-3.90

RSRPPPPPM

11.63

-5.21

-3.99
P53316

PMFPSFGFI

12.58

-5.12

-3.90

IPQVPPVPY

13.08

-6.91

-5.69

VPPVPYIIP

13.09

-5.74

-4.52
P32190

RPSTAPARE

7.96

-7.44

-6.22

RRPSTAPAR

14.33

-3.91

-2.69
P13186

APSYVPNRV

9.87

-4.71

-3.49

LPEREPPTY

12.03

-6.05

-4.83

RPPIPAALP

12.13

-5.76

-4.54
P12630

NPFCLPNSN

14.41

-3.74

-2.52
P39940

DDPRLPSSL

13.46

-4.13

-2.91
P04051

LPHFPKNSK

12.09

-5.21

-3.99

RSLPHFPKN

12.12

-3.23

-2.01

NPAMLPGSS

13.90

-4.26

-3.04
P43603

RFTAPTSPS

14.23

-3.32

-2.10
P07278

KTSTPPLPM

12.93

-5.10

-3.88
P06777

LIPNEPDDI

13.34

-3.83

-2.61
P27999

GSDPTLPRS

13.83

-2.17

-0.95
P47029

PITSPMSNM

12.94

-5.68

-4.46

ILPRDPPSY

13.78

-5.18

-3.96

KHPTPPSLK

13.83

-5.41

-4.19
Q12168

DPYFPQFRS

12.25

-5.08

-3.86

GPPPLPPRA

12.34

-4.45

-3.23

QHPVPKPNI

12.35

-4.82

-3.60
P08458

LPKRKPPKL

10.38

-8.01

-6.79

NLPKRKPPK

13.32

-5.09

-3.87
Q02209

KGPESKPNV

14.40

-3.33

-2.11
Q12496

NIPKKRPFL

10.80

-6.11

-4.89

PSNIPKKRP

13.13

-5.33

-4.11

IPSNIPKKR

14.29

-4.66

-3.44
P32793

HGPTHPSNM

12.80

-3.96

-2.74
P36006

KKPKNPGGL

12.90

-6.56

-5.34

PIPPPPPPM

14.19

-5.99

-4.77

PPPMGQPKD

14.35

-4.96

-3.74
P32875

RTPSKPDPM

11.21

-4.34

-3.12
Q08412

VPPQLPTRT

11.23

-4.98

-3.76

ELPTQPVRK

11.28

-5.16

-3.94

WQPLPPEPL

12.97

-4.99

-3.77
Q06440

RTPKVEPSK

12.13

-4.52

-3.30
P38750

PPGVFPVRG

11.08

-5.79

-4.57

RSPPGVFPV

13.20

-3.10

-1.88

PPILPRTTQ

13.32

-4.77

-3.55
P26570

MEPKSPILK

13.79

-4.71

-3.49

TPSKPNLEV

14.48

-4.63

-3.41

PSTPSKPNL

14.54

-3.19

-1.97
P31374

RKTKPPPPL

10.37

-7.51

-6.29

SPERPSFRQ

11.03

-6.04

-4.82

KPPPPLDFE

13.28

-6.20

-4.98
P38237

DPFVPPPNV

12.85

-5.28

-4.06

NFQIPSKPE

14.06

-3.89

-2.67

FVPPPNVPK

14.29

-6.02

-4.80
P53118

NPHDLPSHL

12.77

-4.63

-3.41
P32389

NHPFEPNFM

12.26

-3.69

-2.47

HPFEPNFMG

14.09

-3.20

-1.98

PPSPAETRG

14.34

-4.01

-2.79
P53933

APPPLPNRQ

11.32

-4.43

-3.21

RRRPPPPPI

12.17

-6.57

-5.35

PPPLPNRQL

13.08

-6.40

-5.18
P32790

LPPIKPPRP

10.26

-6.79

-5.57

PPPAMPARP

13.59

-4.55

-3.33

KPPRPTSTT

13.59

-7.08

-5.86
P33400

TSPQILPPL

12.88

-4.11

-2.89

LPPLPVGIS

14.12

-4.56

-3.34

QPPNAPSYQ

14.33

-4.10

-2.88
P23293

RPSHPQFPI

10.33

-6.14

-4.92

LPLGPQSRY

10.67

-4.96

-3.74

KVPLPLGPQ

13.09

-5.08

-3.86
Q04439

KPAPPPPGM

12.50

-6.57

-5.35

IPTPPQNRD

12.94

-5.13

-3.91

RPSPPTAAT

13.25

-6.01

-4.79
P33338

TPARTPART

10.54

-6.53

-5.31

RTPTPTPPV

12.43

-4.21

-2.99

TPTPTPPVV

14.15

-3.92

-2.70
Q12446

RPVPPPPPM

10.21

-10.18

-8.96

RPLPQLPNR

11.55

-6.23

-5.01

VPPPPPMRT

12.23

-5.55

-4.33
Q04322

PPTLPPRRI

9.42

-7.27

-6.05

TPPTLPPRR

11.05

-5.59

-4.37

TSPPLPPRA

13.51

-1.78

-0.56
Q12373

RPLSQPTTS

13.52

-5.90

-4.68
P41695

HETPVKPSL

12.64

-3.67

-2.45
Q00916

RLFKPRPPL

9.39

-7.10

-5.88

FKPRPPLSY

11.26

-5.46

-4.24

RPTDYPYAK

11.42

-5.17

-3.95
P53901

RPIPPLPTE

11.16

-7.72

-6.50

MAMRPIPPL

11.99

-5.81

-4.59

NDPIILPPT

12.51

-4.82

-3.60
P38990

QPSPIRPVL

12.05

-5.41

-4.19

PSAPSSTRL

12.51

-3.18

-1.96

NQPSPIRPV

14.31

-2.54

-1.32
P47110

TPPRKPSPV

12.52

-6.53

-5.31
P10566

RPIPAIPMD

12.20

-5.62

-4.40

AIPMDLPDY

12.50

-6.53

-5.31

TRPIPAIPM

13.12

-5.33

-4.11
P25558

RHPKSPVKK

11.09

-5.48

-4.26

KSPVKKPMT

12.57

-3.38

-2.16

PKSPVKKPM

13.20

-4.21

-2.99
P40325

RPPRPAANL

8.93

-9.80

-8.58

RPHQRPSTM

9.29

-7.88

-6.66

LPWTYPPRF

10.18

-6.58

-5.36
P37370

RPHMPSVRP

9.23

-8.08

-6.86

RPSPISPSI

10.49

-5.35

-4.13

KVPQNRPHM

11.55

-5.17

-3.95
P47129

GPPLLPPRN

11.91

-4.20

-2.98

RKPNPPPNR

12.66

-5.19

-3.97

KPNPPPNRS

12.74

-4.92

-3.70
P16603

NPSTPVIMI

12.27

-5.30

-4.08

FPNPELPDA

13.68

-4.51

-3.29

LPSNPSTPV

14.17

-4.20

-2.98

 


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