ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-13.PDB
Scoring matrix: RVS167_FMK-SSH-13_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 16.32
Foldx random average score for Saccharomyces cerevisiae: 11.871

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1569623
Proteins after disorder filtering: 4475
 Total fragments: 60956
Proteins after pattern filtering: 2033
 Total fragments: 9249
Proteins after MINT filtering: 69
 Total fragments: 583


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

16.32

-3.00

0.00
Best peptides

RNRIIYWK

0.00

-9.36

-6.36
         
Interactors      
P38140

MNIQPDLP

7.95

-8.38

-5.38

QPDLPPRK

8.48

-9.69

-6.69

PDLPPRKI

11.12

-7.17

-4.17
Q06604

NEEKPLLP

8.36

-10.42

-7.42

KPLLPTRP

8.55

-9.43

-6.43

GPRMPSRG

8.87

-8.91

-5.91
Q12365

IVPREPLR

8.86

-7.98

-4.98

IPFIPPQE

9.32

-8.10

-5.10

QIPFIPPQ

9.52

-6.82

-3.82
P40072

TPSASPML

11.45

-6.57

-3.57
P40956

NPKNVPFP

7.04

-8.35

-5.35

TPPLPRRR

8.41

-10.55

-7.55

STPPLPRR

9.89

-6.07

-3.07
Q06833

RRPVPRRP

7.31

-10.97

-7.97

RRPSQPLN

7.74

-8.76

-5.76

RPSQPLNT

9.62

-7.95

-4.95
P40032

FPSILPNV

8.10

-7.68

-4.68

RLFPSILP

9.29

-7.17

-4.17

ILPNVPHS

9.38

-6.95

-3.95
P32628

EPPIAPES

11.83

-6.77

-3.77
Q12242

KPCDVPNN

10.90

-6.07

-3.07
P38266

MPPPKPFR

5.90

-10.61

-7.61

LPPPKPFR

6.36

-11.25

-8.25

QPPPKPFR

7.40

-9.19

-6.19
P15891

TPEKKPKE

8.22

-7.18

-4.18

QPPLPSRN

9.11

-10.04

-7.04

KEPVKTPS

9.79

-6.77

-3.77
P53169

MPTLPPRP

7.37

-10.72

-7.72

SVPIMPTL

8.69

-6.12

-3.12

ANSVPIMP

8.76

-6.94

-3.94
P39692

SPKQPVIM

9.55

-8.03

-5.03

LPPSPKQP

10.85

-8.21

-5.21

PKQPVIMS

11.30

-6.60

-3.60
P38872

CLPNLYPH

9.51

-6.33

-3.33

TLPLPNPY

10.45

-8.15

-5.15

NCLPNLYP

10.83

-5.05

-2.05
P17555

RPKKPSTL

8.98

-9.57

-6.57

GPPPRPKK

9.87

-8.30

-5.30

PPPRPKKP

9.92

-9.27

-6.27
Q12344

SPPLPPRQ

8.25

-9.68

-6.68

SPKLPPRG

8.38

-9.04

-6.04

TTSSPPLP

10.72

-6.01

-3.01
P38289

DPENPSFI

8.90

-8.82

-5.82
Q03780

RPPPPPMD

7.14

-10.74

-7.74

PPPPMDMK

8.52

-9.97

-6.97

APDIPPRS

8.93

-9.14

-6.14
P53316

MPMFPSFG

6.54

-11.14

-8.14

VPYIIPPQ

8.53

-8.14

-5.14

VPPVPYII

9.27

-8.27

-5.27
P32190

RPSTAPAR

11.70

-8.55

-5.55
P13186

RPPIPAAL

8.29

-10.66

-7.66

NIPLTPLA

9.25

-6.75

-3.75

QNNIPLTP

10.07

-6.79

-3.79
P12630

NPFCLPNS

10.27

-6.64

-3.64

SNPFCLPN

11.17

-3.88

-0.88
P39940

TWDDPRLP

9.70

-6.71

-3.71

DDPRLPSS

10.26

-4.43

-1.43

DPRLPSSL

10.80

-7.81

-4.81
P04051

DRSLPHFP

8.22

-10.58

-7.58

LPHFPKNS

10.02

-8.72

-5.72

NPAMLPGS

10.65

-7.00

-4.00
P43603

RFTAPTSP

10.72

-6.53

-3.53
P07278

STPPLPMH

8.78

-7.15

-4.15

TPPLPMHF

9.10

-9.61

-6.61

KTSTPPLP

10.46

-7.43

-4.43
P06777

LIPNEPDD

11.36

-4.56

-1.56
P27999

SDPTLPRS

8.77

-6.66

-3.66

IGSDPTLP

11.80

-5.48

-2.48
P47029

GPKLPNLP

8.93

-9.38

-6.38

KLPNLPND

9.44

-6.36

-3.36

HPTPPSLK

9.82

-8.37

-5.37
Q12168

DPYFPQFR

7.65

-10.11

-7.11

DNDDPYFP

7.69

-7.20

-4.20

PPPLPPRA

9.11

-9.96

-6.96
Q04322

SPPLPPRA

8.28

-9.80

-6.80

PPTLPPRR

9.39

-9.61

-6.61

APLDRPQL

10.89

-6.42

-3.42
P08458

LPKRKPPK

8.29

-9.57

-6.57

TNLPKRKP

8.63

-4.91

-1.91

PKRKPPKL

9.73

-7.72

-4.72
Q02209

YKGPESKP

10.14

-5.99

-2.99

PESKPNVN

11.17

-7.96

-4.96

GPESKPNV

11.60

-5.86

-2.86
Q12496

IPKKRPFL

7.06

-10.63

-7.63

IPSNIPKK

7.85

-8.14

-5.14

SNIPKKRP

8.39

-3.76

-0.76
P36006

QPKDPKFE

8.79

-8.87

-5.87

NIPIPPPP

9.69

-7.36

-4.36

SNKKPKNP

9.87

-6.95

-3.95
P32875

TNRTPSKP

9.03

-5.80

-2.80

RTPSKPDP

10.25

-4.15

-1.15

TPSKPDPM

11.48

-6.98

-3.98
Q08412

LPTQPVRK

9.00

-8.70

-5.70

KNSRPQQP

9.68

-6.67

-3.67

WQPLPPEP

9.95

-8.24

-5.24
Q06440

RTPKVEPS

10.12

-5.26

-2.26

TPKVEPSK

10.73

-5.41

-2.41
P38750

LPHNLPHN

8.30

-8.59

-5.59

RSPPGVFP

11.26

-7.32

-4.32

PPILPRTT

11.57

-8.43

-5.43
P26570

MEPKSPIL

9.14

-8.85

-5.85

TPSKPNLE

9.22

-9.32

-6.32

EPKSPILK

10.15

-8.27

-5.27
P31374

SPERPSFR

7.72

-9.86

-6.86

PDDLPPLK

7.88

-8.49

-5.49

TPVFPNLD

8.91

-9.06

-6.06
P38237

NFQIPSKP

8.83

-7.11

-4.11

PPPNVPKK

9.23

-7.48

-4.48

NDPFVPPP

9.52

-7.20

-4.20
P34223

MPDNEPKQ

8.92

-7.12

-4.12

SPAEVPKN

10.22

-6.50

-3.50
P53118

NPHDLPSH

10.45

-5.88

-2.88

PHDLPSHL

11.26

-6.74

-3.74
P32389

HPFEPNFM

9.00

-9.37

-6.37

NHPFEPNF

10.84

-4.57

-1.57

PFEPNFMG

10.92

-6.23

-3.23
P53933

RPPPPPIP

7.39

-10.07

-7.07

RVAPPPLP

7.80

-8.49

-5.49

NDLPMELP

8.31

-8.58

-5.58
P32790

LPPIKPPR

8.01

-9.06

-6.06

PPIKPPRP

9.66

-8.34

-5.34

PPAMPARP

9.83

-8.62

-5.62
P33400

PQILPPLP

9.27

-8.95

-5.95

SPQILPPL

9.45

-6.88

-3.88

ILPPLPVG

10.03

-6.76

-3.76
P23293

RPSHPQFP

6.83

-10.49

-7.49

IPRGPKKD

10.96

-8.09

-5.09

KVPLPLGP

11.32

-7.24

-4.24
Q04439

SKPKEPMF

8.67

-7.67

-4.67

KPKEPMFE

8.84

-9.50

-6.50

NNNIPTPP

9.90

-6.73

-3.73
P33338

RTPARTPT

11.13

-5.15

-2.15

RTPTPTPP

11.22

-7.27

-4.27

TPTPPVVA

11.48

-6.85

-3.85
Q12446

KHSLPPLP

8.46

-9.00

-6.00

RNNRPVPP

8.52

-6.76

-3.76

NRPLPQLP

8.52

-10.20

-7.20
P22219

NPDFPYNN

10.06

-6.77

-3.77

SPGETPYL

10.88

-6.66

-3.66
P53220

NKPKPLWP

7.69

-9.48

-6.48
Q12373

SKRPLSQP

10.15

-5.98

-2.98

RPLSQPTT

10.36

-6.52

-3.52
P41695

TPVKPSLT

8.93

-8.96

-5.96

ETPVKPSL

11.54

-3.01

-0.01
Q00916

FKPRPPLS

8.13

-9.40

-6.40

RLFKPRPP

8.74

-9.12

-6.12

PRPPLSYK

8.81

-8.00

-5.00
P53901

MRPIPPLP

6.21

-10.88

-7.88

SPKLPPLP

7.57

-9.51

-6.51

LPPIPTRD

7.81

-10.23

-7.23
P38990

SPIRPVLP

8.47

-8.57

-5.57

NLPKIPNS

8.70

-7.05

-4.05

NQNLPKIP

9.50

-8.83

-5.83
P47110

TPPRKPSP

9.24

-6.25

-3.25

PPRKPSPV

11.30

-7.57

-4.57

PNSPKETD

11.78

-3.53

-0.53
P10566

TRPIPAIP

8.04

-9.15

-6.15

PIPAIPMD

8.93

-8.07

-5.07

PAIPMDLP

10.76

-7.69

-4.69
P25693

RPIPTIKP

10.02

-6.66

-3.66
P25558

SPVKKPMT

7.12

-8.21

-5.21

YNPSQPVT

8.86

-4.83

-1.83

RHPKSPVK

9.82

-7.07

-4.07
P40325

QNPSLPWT

7.22

-6.54

-3.54

RPPPRPQQ

8.43

-10.72

-7.72

QPPRPPRP

8.83

-9.11

-6.11
P37370

MPKPRPFQ

6.93

-9.75

-6.75

APPLPTFS

7.65

-11.06

-8.06

RPHMPSVR

7.81

-9.38

-6.38
Q08446

HSPISPLK

10.67

-6.02

-3.02
P39743

SNPLTSPV

11.44

-3.78

-0.78
P47129

LPNRKPNP

8.67

-7.31

-4.31

PPLLPPRN

9.43

-9.30

-6.30

RKPNPPPN

9.69

-7.23

-4.23
P16603

NFPNPELP

8.89

-7.85

-4.85

NFRLPSNP

9.19

-7.56

-4.56

NPSTPVIM

10.38

-8.41

-5.41

 


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