ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-12.PDB
Scoring matrix: RVS167_FMK-SSH-12_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 10.22
Foldx random average score for Saccharomyces cerevisiae: 8.551

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1475719
Proteins after disorder filtering: 4579
 Total fragments: 83597
Proteins after pattern filtering: 2268
 Total fragments: 15818
Proteins after MINT filtering: 73
 Total fragments: 961


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

10.22

-1.63

0.00
Best peptides

YRWRRWYR

0.00

-4.87

-3.24
         
Interactors      
P38140

PDLPPRKI

4.49

-4.53

-2.90

NIQPDLPP

5.04

-4.10

-2.47

NIPPHPYP

5.53

-3.68

-2.05
Q06604

PRMPSRGR

2.79

-5.82

-4.19

SSPPPLPT

3.91

-5.65

-4.02

EEKPLLPT

4.03

-5.54

-3.91
Q12365

IVPREPLR

5.07

-4.52

-2.89

DIPGKFPS

6.33

-4.61

-2.98

VPREPLRN

6.78

-5.81

-4.18
P40072

PSASPMLD

6.96

-3.92

-2.29

AAPPTTKP

7.86

-3.29

-1.66

PTTKPGTN

7.90

-0.55

1.08
P40956

TSTPPLPR

3.77

-3.81

-2.18

PPLPRRRA

5.02

-5.99

-4.36

PKNVPFPF

5.52

-2.79

-1.16
Q06833

PRRPSQPL

4.99

-4.01

-2.38

PVPRRPSQ

5.28

-4.94

-3.31

RRPVPRRP

5.50

-5.58

-3.95
P40032

LFPSILPN

5.92

-3.57

-1.94

RLFPSILP

5.98

-4.13

-2.50

SILPNVPH

5.98

-3.44

-1.81
P32628

PIAPESAT

8.40

-2.34

-0.71
Q12242

TKPCDVPN

6.31

-2.42

-0.79

GTKPCDVP

8.27

-2.91

-1.28
P38266

NIMPPPKP

4.23

-5.54

-3.91

KSFPPPPL

4.41

-4.43

-2.80

PILPPRNN

4.51

-4.70

-3.07
P25333

DKYPEGAP

6.43

-3.35

-1.72

AITPAPTP

6.68

-1.82

-0.19

ITPAPTPT

7.98

-2.97

-1.34
P16603

FRLPSNPS

5.14

-3.63

-2.00

PELPDAPP

5.64

-3.83

-2.20

FPNPELPD

6.23

-4.31

-2.68
P39692

MKLPPSPK

4.87

-3.65

-2.02

KLPPSPKQ

6.12

-3.49

-1.86

PSPKQPVI

6.38

-3.30

-1.67
P38872

NCLPNLYP

3.83

-5.33

-3.70

GTLPLPNP

5.70

-4.00

-2.37

CLPNLYPH

6.51

-3.35

-1.72
P17555

SGPPPRPK

4.58

-4.81

-3.18

PRPKKPST

5.42

-3.45

-1.82

PAPPPPPP

5.72

-4.16

-2.53
Q12344

PKLPPRGK

3.35

-4.89

-3.26

TSPKLPPR

5.26

-3.61

-1.98

SSPPLPPR

5.38

-4.11

-2.48
P38289

PENPSFIN

6.05

-3.17

-1.54

DVPTNDPS

8.53

-2.62

-0.99
Q03780

SRPPPPPM

4.67

-4.28

-2.65

KRSRPPPP

5.45

-3.53

-1.90

PPPPPMDM

5.94

-5.62

-3.99
P53316

WMMPMFPS

3.82

-6.34

-4.71

PMFPSFGF

4.54

-4.94

-3.31

FGFIPQVP

6.21

-4.24

-2.61
P32190

LRRPSTAP

6.38

-3.20

-1.57
Q12389

LEDPSQGP

7.81

-1.91

-0.28
P13186

FKAPSYVP

5.42

-3.27

-1.64

EPLPEREP

5.63

-4.47

-2.84

PIPAALPP

5.68

-4.59

-2.96
P12630

SNPFCLPN

6.73

-4.26

-2.63

NPFCLPNS

7.27

-3.74

-2.11
P39940

PRLPSSLD

6.03

-2.95

-1.32

WDDPRLPS

6.13

-3.62

-1.99

DDPRLPSS

6.16

-5.53

-3.90
P04051

RSLPHFPK

4.29

-5.41

-3.78

SVNPAMLP

5.95

-4.43

-2.80

VNPAMLPG

6.34

-4.47

-2.84
P43603

TAPTSPST

7.60

-2.71

-1.08

FTAPTSPS

8.45

-2.41

-0.78
P15891

AAPPPPPR

5.29

-4.22

-2.59

AAQPPLPS

5.29

-4.81

-3.18

VKTPSPAP

5.67

-2.29

-0.66
P07278

TSTPPLPM

4.27

-3.72

-2.09

STPPLPMH

6.31

-3.94

-2.31

TPPLPMHF

6.41

-5.22

-3.59
P06777

LIPNEPDD

8.14

-2.66

-1.03
P27999

GSDPTLPR

6.00

-3.39

-1.76

PTLPRSDR

6.28

-3.03

-1.40

DPTLPRSD

7.56

-3.09

-1.46
Q12532

PFKPYING

6.58

-4.17

-2.54
Q12168

PYFPQFRS

4.19

-5.08

-3.45

RGPPPLPP

4.99

-5.51

-3.88

PPLPPRAN

5.32

-4.67

-3.04
Q04322

PTLPPRRI

3.99

-6.34

-4.71

STPPTLPP

4.62

-5.31

-3.68

PPLPPRAD

5.36

-4.14

-2.51
P08458

TNLPKRKP

4.72

-4.89

-3.26

PKRKPPKL

4.76

-3.58

-1.95

NLPKRKPP

5.19

-3.20

-1.57
Q02209

KGPESKPN

7.58

-3.34

-1.71

YKGPESKP

8.21

-1.43

0.20

PESKPNVN

8.24

-1.61

0.02
P47029

PKLPNLPN

3.10

-5.04

-3.41

PTPPSLKA

4.52

-5.41

-3.78

ILPRDPPS

5.19

-4.58

-2.95
P32793

HGPTHPSN

7.54

-2.78

-1.15

PTHPSNMS

7.69

-2.93

-1.30
P36006

PIPPPPPP

5.45

-4.30

-2.67

PPPPPMGQ

5.66

-5.64

-4.01

KKPKNPGG

5.88

-3.62

-1.99
P32875

NRTPSKPD

5.18

-2.34

-0.71

SKPDPMEP

5.83

-3.81

-2.18

PSKPDPME

6.32

-3.29

-1.66
Q08412

KKWQPLPP

2.99

-3.99

-2.36

DVPPQLPT

4.49

-5.06

-3.43

PQLPTRTK

5.04

-4.15

-2.52
Q06440

DRTPKVEP

6.79

-1.06

0.57

TPKVEPSK

7.78

-3.34

-1.71

RTPKVEPS

8.40

-2.63

-1.00
Q12496

NIPKKRPF

4.72

-4.23

-2.60

EIPSNIPK

6.95

-4.08

-2.45

PSNIPKKR

7.03

-3.21

-1.58
P26570

PSKPNLEV

5.37

-4.60

-2.97

PKSPILKT

5.64

-3.79

-2.16

MEPKSPIL

5.90

-3.89

-2.26
P31374

PERPSFRQ

4.46

-4.63

-3.00

PVFPNLDP

4.48

-5.27

-3.64

FEQPRLPS

4.49

-4.26

-2.63
P38237

DPFVPPPN

6.46

-4.00

-2.37

FVPPPNVP

6.89

-2.56

-0.93

PSKPENTV

7.18

-3.21

-1.58
P34223

QPMPDNEP

7.08

-4.18

-2.55

SSPAEVPK

7.40

-2.83

-1.20

TDPSDPNS

8.23

-2.78

-1.15
P53118

ENPHDLPS

6.57

-4.05

-2.42

VENPHDLP

8.04

-2.18

-0.55
P32389

GSPSQFPA

6.26

-4.07

-2.44

PFEPNFMG

7.52

-3.59

-1.96

NHPFEPNF

7.73

-2.68

-1.05
P53933

TRRRPPPP

3.77

-4.93

-3.30

DLPMELPH

4.03

-4.43

-2.80

VAPPPLPN

4.26

-5.35

-3.72
P32790

PAMPARPT

3.96

-5.53

-3.90

PIKPPRPT

4.63

-4.43

-2.80

IKPPRPTS

5.15

-4.24

-2.61
P33400

QILPPLPV

3.15

-5.11

-3.48

TSPQILPP

5.80

-4.22

-2.59

ILPPLPVG

6.62

-3.12

-1.49
P23293

PSHPQFPI

5.17

-4.62

-2.99

AIPRGPKK

5.24

-5.41

-3.78

KVPLPLGP

5.60

-3.88

-2.25
Q04439

SKKPAPPP

5.11

-3.52

-1.89

SKPKEPMF

5.24

-3.33

-1.70

NIPPPPPP

5.37

-3.50

-1.87
P33338

ARTPARTP

4.87

-2.02

-0.39

ARTPTPTP

6.15

-1.93

-0.30

PTPTPPVV

7.11

-1.62

0.01
Q12446

HSLPPLPN

3.10

-5.21

-3.58

VRLPAPPP

4.18

-3.58

-1.95

PIPPTLPS

4.83

-5.33

-3.70
P22219

PDFPYNNS

7.31

-3.39

-1.76

VSPGETPY

8.27

-2.87

-1.24

PGETPYLI

8.44

-1.72

-0.09
P53220

NKPKPLWP

3.68

-5.47

-3.84
Q12373

KRPLSQPT

6.15

-3.52

-1.89

SKRPLSQP

6.75

-2.82

-1.19
P41695

PVKPSLTS

4.89

-4.95

-3.32

HETPVKPS

6.07

-2.17

-0.54

ETPVKPSL

7.15

-2.96

-1.33
Q00916

RLFKPRPP

4.34

-4.93

-3.30

FKPRPPLS

4.54

-3.68

-2.05

KRPTDYPY

4.94

-3.63

-2.00
P53901

PKLPPLPT

2.45

-5.35

-3.72

MAMRPIPP

3.40

-5.60

-3.97

YNQPPLPP

5.22

-4.98

-3.35
P38990

QNLPKIPN

5.34

-3.67

-2.04

PNLPSAPS

6.72

-2.97

-1.34

NLPKIPNS

6.79

-3.11

-1.48
P47110

TSTPPRKP

4.94

-3.44

-1.81

STPPRKPS

5.30

-4.55

-2.92

TPPRKPSP

6.58

-5.42

-3.79
P10566

AIPMDLPD

4.13

-4.98

-3.35

TRPIPAIP

7.25

-3.05

-1.42

IPAIPMDL

7.79

-4.32

-2.69
Q07821

SQRPGKKP

6.13

-3.91

-2.28
P25558

PVKKPMTS

4.50

-5.20

-3.57

EELPNTPR

5.66

-4.26

-2.63

KSPVKKPM

6.53

-3.41

-1.78
P40325

PRPPPRPQ

3.74

-5.03

-3.40

SQPRPPPR

4.61

-5.55

-3.92

PRPPRPAA

5.11

-4.22

-2.59
P38750

DTFPHNAP

6.05

-4.21

-2.58

PILPRTTQ

6.37

-3.44

-1.81

GLPHNLPH

6.55

-3.86

-2.23
P37370

PKPRPFQN

3.61

-6.26

-4.63

SSMPAPPP

4.43

-5.04

-3.41

QNRPHMPS

4.56

-5.47

-3.84
Q08446

HSPISPLK

6.85

-2.93

-1.30

SSHSPISP

7.19

-2.22

-0.59
P39743

NPLTSPVA

7.64

-3.14

-1.51

YSNPLTSP

8.32

-1.07

0.56
P47129

NTLPNRKP

4.43

-5.13

-3.50

SGPPLLPP

4.60

-5.03

-3.40

PLLPPRNT

4.62

-4.21

-2.58
P53169

PIMPTLPP

3.33

-6.33

-4.70

PTLPPRPY

3.74

-4.77

-3.14

IMPTLPPR

6.76

-2.36

-0.73

 


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