ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: RVS167_FMK-SSH-10.PDB
Scoring matrix: RVS167_FMK-SSH-10_mat
Uniprot code: P39743
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 11.54
Foldx random average score for Saccharomyces cerevisiae: 17.945

Available information for P39743 in MINT (Nov 2008):
Nš of interacting proteins: 118
 Proteins belonging to other specie: 1
Nš of interactions described: 305
 Interactions with other species: 1

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 2035436
Proteins after disorder filtering: 4897
 Total fragments: 193811
Proteins after pattern filtering: 2337
 Total fragments: 20456
Proteins after MINT filtering: 73
 Total fragments: 1155


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

11.54

-1.17

0.00
Best peptides

RPKKCPMR

0.00

-2.81

-1.64
         
Interactors      
P38140

QPDLPPRK

6.84

-6.00

-4.83

MNIQPDLP

8.16

-4.94

-3.77

IPPHPYPS

10.21

-4.26

-3.09
Q06604

KPLLPTRP

6.71

-6.71

-5.54

LPTRPNKA

6.78

-6.71

-5.54

RVKPAPPV

6.87

-6.64

-5.47
Q12365

IPFIPPQE

7.10

-6.08

-4.91

VPREPLRN

7.73

-5.82

-4.65

KDIPGKFP

8.90

-3.55

-2.38
P40072

TPSASPML

7.35

-3.83

-2.66

PTTKPGTN

11.08

-3.65

-2.48

PSASPMLD

11.09

-2.44

-1.27
P40956

TPPLPRRR

6.96

-7.56

-6.39

WNPKNVPF

10.25

1.52

2.69

TTSTPPLP

10.54

-4.02

-2.85
Q06833

RRPVPRRP

5.18

-8.39

-7.22

VPRRPSQP

7.09

-5.62

-4.45

RPSQPLNT

7.25

-6.72

-5.55
P40032

RLFPSILP

5.45

-4.64

-3.47

LPNVPHSD

10.08

-4.30

-3.13

PSILPNVP

11.42

-3.50

-2.33
P32628

EPPIAPES

7.20

-4.85

-3.68

PPIAPESA

11.64

-4.01

-2.84

PIAPESAT

16.59

1.14

2.31
Q12242

GTKPCDVP

9.87

-1.83

-0.66

PCDVPNNG

13.22

-4.04

-2.87

KPCDVPNN

14.17

-2.79

-1.62
P38266

FPPPPLKP

5.93

-4.94

-3.77

PPPKPFRR

5.99

-6.64

-5.47

PPPKPFRH

6.11

-6.43

-5.26
P25333

YPEGAPTS

8.16

-4.36

-3.19

AITPAPTP

8.42

-3.50

-2.33

KYPEGAPT

10.12

-3.94

-2.77
P16603

LPDAPPVV

8.42

-5.57

-4.40

NPSTPVIM

8.52

-3.95

-2.78

LPSNPSTP

9.13

-4.59

-3.42
P39692

KLPPSPKQ

7.29

-3.89

-2.72

SPKQPVIM

7.92

-3.88

-2.71

LPPSPKQP

8.74

-4.78

-3.61
P38872

NCLPNLYP

10.66

2.65

3.82

TLPLPNPY

12.12

-3.37

-2.20

PNLYPHGT

12.71

-3.10

-1.93
P17555

RPKKPSTL

5.04

-5.74

-4.57

PPPRPKKP

7.26

-6.23

-5.06

KSGPPPRP

7.97

-4.58

-3.41
Q12344

SPKLPPRG

7.36

-4.91

-3.74

SPPLPPRQ

7.74

-5.02

-3.85

PPLPPRQN

8.33

-6.70

-5.53
P38289

DPENPSFI

9.18

-3.90

-2.73

PENPSFIN

9.83

-2.17

-1.00

YDVPTNDP

13.48

-2.91

-1.74
Q03780

RPPPPPMD

4.14

-7.40

-6.23

APDIPPRS

6.90

-6.53

-5.36

IPPRSPNR

7.93

-5.19

-4.02
P53316

MPMFPSFG

6.90

-5.70

-4.53

VPPVPYII

7.91

-5.49

-4.32

IPQVPPVP

8.05

-5.88

-4.71
P32190

RPSTAPAR

5.36

-5.29

-4.12

LRRPSTAP

8.82

-3.41

-2.24

PSTAPARE

10.51

-3.19

-2.02
Q12389

DPSQGPAA

9.48

-3.33

-2.16

LEDPSQGP

11.39

-1.80

-0.63

PSQGPAAN

13.27

-2.00

-0.83
P13186

PPIPAALP

6.00

-5.54

-4.37

RPPIPAAL

6.46

-6.79

-5.62

FKAPSYVP

8.91

-4.42

-3.25
P12630

SNPFCLPN

10.40

-0.42

0.75

PFCLPNSN

12.78

-3.46

-2.29
P39940

PRLPSSLD

8.44

-2.07

-0.90

TWDDPRLP

10.53

-4.13

-2.96

DPRLPSSL

10.74

-3.62

-2.45
P04051

SVNPAMLP

8.24

-4.69

-3.52

DRSLPHFP

9.22

-4.93

-3.76

LPHFPKNS

9.57

-5.92

-4.75
P43603

RFTAPTSP

9.74

-4.27

-3.10

APTSPSTS

10.51

-2.84

-1.67

TAPTSPST

12.55

-1.87

-0.70
P15891

APPPPPRR

6.87

-5.88

-4.71

TPSKSPAP

7.48

-3.65

-2.48

PPPPPRRA

7.55

-5.92

-4.75
P07278

TPPLPMHF

8.40

-5.60

-4.43

KTSTPPLP

9.65

-4.44

-3.27

TSTPPLPM

11.54

-2.87

-1.70
P06777

IPNEPDDI

10.72

-4.28

-3.11

PNEPDDIE

14.05

2.67

3.84

LIPNEPDD

16.42

2.29

3.46
P27999

DPTLPRSD

10.81

-6.04

-4.87

IGSDPTLP

12.01

-3.01

-1.84

GSDPTLPR

13.31

-0.77

0.40
P47029

HPTPPSLK

6.95

-4.09

-2.92

SPITSPMS

7.71

-3.16

-1.99

PRDPPSYK

8.30

-4.61

-3.44
Q12168

PPPLPPRA

7.56

-6.84

-5.67

NRGPPPLP

7.69

-4.58

-3.41

PPPVPNRP

8.41

-6.35

-5.18
Q04322

PPTLPPRR

6.88

-6.83

-5.66

TPSKSPTS

7.54

-3.60

-2.43

SPPLPPRA

7.80

-5.09

-3.92
P08458

PKRKPPKL

7.84

-5.84

-4.67

LPKRKPPK

9.95

1.36

2.53

TNLPKRKP

11.21

2.41

3.58
Q02209

PESKPNVN

10.80

-4.35

-3.18

KGPESKPN

12.75

-1.75

-0.58

GPESKPNV

13.53

4.69

5.86
Q12496

PSNIPKKR

9.29

-4.48

-3.31

PEIPSNIP

10.23

-2.55

-1.38

SNIPKKRP

11.93

1.34

2.51
P32793

PTHPSNMS

10.41

-2.99

-1.82

GPTHPSNM

10.59

-2.84

-1.67

LGHGPTHP

11.96

-3.20

-2.03
P36006

PPPPPPMG

6.98

-5.93

-4.76

IPIPPPPP

8.83

-6.21

-5.04

IPPPPPPM

9.17

-6.63

-5.46
P32875

TPSKPDPM

9.35

-4.44

-3.27

TNRTPSKP

9.51

-3.56

-2.39

NRTPSKPD

10.61

-2.62

-1.45
Q08412

LPTQPVRK

6.24

-6.33

-5.16

PPQLPTRT

8.17

-5.79

-4.62

KNSRPQQP

8.75

-3.93

-2.76
Q06440

DRTPKVEP

12.86

5.05

6.22

RTPKVEPS

13.24

-4.25

-3.08

TPKVEPSK

14.63

0.56

1.73
P38750

RSPPGVFP

6.34

-4.92

-3.75

FPHNAPAS

7.01

-3.75

-2.58

PPILPRTT

9.20

-5.54

-4.37
P26570

MEPKSPIL

7.02

-4.22

-3.05

TPSKPNLE

7.37

-5.42

-4.25

EPKSPILK

8.07

-4.05

-2.88
P31374

SPERPSFR

6.87

-5.00

-3.83

RKTKPPPP

7.30

-7.14

-5.97

KPGTPVFP

7.69

-4.83

-3.66
P38237

NFQIPSKP

8.26

-4.74

-3.57

PPNVPKKD

8.56

-5.93

-4.76

IPSKPENT

8.95

-5.11

-3.94
P34223

ESSPAEVP

9.56

-3.75

-2.58

SPAEVPKN

12.18

-2.06

-0.89

MPDNEPKQ

12.41

-0.32

0.85
P53118

PHDLPSHL

9.28

-4.50

-3.33

ENPHDLPS

16.14

3.29

4.46

VENPHDLP

17.54

-0.18

0.99
P32389

PPSPAETR

7.99

-5.15

-3.98

HPFEPNFM

8.48

-2.89

-1.72

MGSPSQFP

9.39

-2.30

-1.13
P53933

RPPPPPIP

4.52

-7.17

-6.00

RVAPPPLP

6.25

-6.96

-5.79

RRRPPPPP

7.06

-7.51

-6.34
P32790

PPIKPPRP

5.75

-6.46

-5.29

PPAMPARP

7.01

-6.89

-5.72

KPPRPTST

8.88

-5.11

-3.94
P33400

PQILPPLP

9.00

-4.74

-3.57

PPNAPSYQ

9.22

-5.08

-3.91

QPPNAPSY

9.40

-4.45

-3.28
P23293

RPSHPQFP

5.80

-5.67

-4.50

AIPRGPKK

7.30

-4.79

-3.62

FPISPSQG

7.95

-2.88

-1.71
Q04439

KPKEPMFE

7.01

-5.09

-3.92

RPSPPTAA

7.10

-5.31

-4.14

PPPPSSKP

7.43

-4.14

-2.97
P33338

ARTPARTP

8.02

-4.60

-3.43

TPTPPVVA

8.81

-4.75

-3.58

TPARTPTP

9.49

-3.08

-1.91
Q12446

VPPPPPMR

6.13

-6.51

-5.34

RRGPAPPP

6.15

-5.71

-4.54

PPPPAFLT

6.22

-5.57

-4.40
P22219

NPDFPYNN

9.95

-3.44

-2.27

SPGETPYL

10.43

1.19

2.36

AVSPGETP

11.10

-3.44

-2.27
P53220

NKPKPLWP

8.16

-5.68

-4.51
Q12373

KRPLSQPT

10.42

-2.78

-1.61

PLSQPTTS

11.02

-3.42

-2.25

RPLSQPTT

17.46

1.58

2.75
P41695

TPVKPSLT

6.33

-5.80

-4.63

AHETPVKP

8.98

-3.41

-2.24

PVKPSLTS

10.68

-2.41

-1.24
Q00916

RLFKPRPP

6.75

-6.96

-5.79

FKPRPPLS

7.06

-6.16

-4.99

KPRPPLSY

8.85

-4.85

-3.68
P53901

MRPIPPLP

6.06

-5.83

-4.66

LPPIPTRD

6.73

-7.26

-6.09

RPIPPLPT

7.13

-5.17

-4.00
P38990

SPIRPVLP

7.13

-4.96

-3.79

IPSPAKNP

8.14

-5.97

-4.80

VPNLPSAP

9.39

-5.17

-4.00
P47110

TSTPPRKP

8.79

-5.64

-4.47

PPRKPSPV

8.90

-5.39

-4.22

KPNSPKET

9.81

-4.23

-3.06
P10566

RPIPAIPM

5.56

-5.30

-4.13

TRPIPAIP

7.88

-4.63

-3.46

IPAIPMDL

9.07

-5.78

-4.61
P25693

RPIPTIKP

5.95

-3.17

-2.00
Q07821

SQRPGKKP

9.25

-3.86

-2.69
P25558

RHPKSPVK

4.66

-4.77

-3.60

HPKSPVKK

7.89

-2.99

-1.82

SPVKKPMT

8.46

5.12

6.29
P40325

RPPRPAAN

6.19

-5.38

-4.21

QPPRPPRP

6.29

-5.87

-4.70

QPRPPPRP

6.60

-6.35

-5.18
P37370

RPHMPSVR

4.92

-6.73

-5.56

PPLPAAMS

5.90

-5.59

-4.42

APPIPGMG

7.21

-6.25

-5.08
Q08446

HSPISPLK

8.06

-3.29

-2.12

SSHSPISP

13.15

-1.30

-0.13
P39743

NPLTSPVA

9.02

-2.84

-1.67

SNPLTSPV

13.81

-0.62

0.55
P47129

PPLLPPRN

7.43

-5.94

-4.77

KPNPPPNR

8.21

-5.66

-4.49

TSGPPLLP

9.43

-3.82

-2.65
P53169

MPTLPPRP

5.60

-6.94

-5.77

VPIMPTLP

6.77

-6.78

-5.61

ANSVPIMP

8.86

-4.80

-3.63

 


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