ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1ZX6-8.PDB
Scoring matrix: PIN3_1ZX6-8_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 10.29
Foldx random average score for Saccharomyces cerevisiae: 8.940

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1680096
Proteins after disorder filtering: 4710
 Total fragments: 117195
Proteins after pattern filtering: 2292
 Total fragments: 17356
Proteins after MINT filtering: 25
 Total fragments: 514


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

10.29

1.28

0.00

Best peptides

WRPPMGKF

0.00

-5.04

-6.32

         
Interactors      
Q06604

SPPPLPTR

3.87

-5.95

-7.23

EKPLLPTR

4.40

-5.51

-6.79

KGPRMPSR

5.05

-5.55

-6.83

P24583

ANAPLPPQ

5.61

-2.97

-4.25

APLPPQPR

5.63

-2.33

-3.61

LPPQPRKH

6.09

-4.23

-5.51

P38260

GGPDDPTL

7.09

-3.60

-4.88

Q04322

TPPTLPPR

3.85

-6.61

-7.89

TSPPLPPR

4.72

-5.79

-7.07

APLDRPQL

5.80

-4.42

-5.70

Q12168

GPPPLPPR

3.17

-6.27

-7.55

HPVPKPNI

4.03

-4.80

-6.08

IPPPVPNR

4.09

-5.48

-6.76

P15891

APPPPPRR

4.71

-5.13

-6.41

AQPPLPSR

5.09

-6.71

-7.99

AAPPPPPR

5.46

-4.68

-5.96

Q12344

SSPPLPPR

4.70

-5.74

-7.02

TSPKLPPR

5.19

-6.02

-7.30

SPPLPPRQ

5.90

-3.52

-4.80

P39521

QPKPKPAQ

4.91

-4.30

-5.58

PHVPDRPP

6.14

-3.25

-4.53

DAQPKPKP

6.20

-4.28

-5.56

P40325

PRPPRPAA

4.10

-5.48

-6.76

RPPPRPQQ

4.63

-6.36

-7.64

PRPPPRPQ

4.71

-3.09

-4.37

Q08601

YNRPVYPP

4.64

-2.99

-4.27

NRPVYPPP

5.28

-4.35

-5.63

PPPGPPPM

5.36

-5.01

-6.29

P19812

EPRPRRIP

5.23

-3.72

-5.00

RPRRIPPT

5.57

-3.71

-4.99

PRRIPPTD

6.45

-1.73

-3.01

Q12412

PPQPPPAY

6.08

-3.11

-4.39

QPPPAYDP

6.24

-4.18

-5.46

YDPNHRPP

6.44

-3.53

-4.81

Q08412

VPPQLPTR

4.51

-6.16

-7.44

QPLPPEPL

6.44

-1.52

-2.80

EDVPPQLP

6.69

-1.33

-2.61

P53118

ENPHDLPS

6.00

-3.38

-4.66

NPHDLPSH

6.42

-3.14

-4.42

VENPHDLP

7.22

-1.35

-2.63

P38216

SRPSNPPP

5.27

-5.68

-6.96

YSRPSNPP

8.57

-1.73

-3.01

RPSNPPPS

8.62

-2.12

-3.40

P53933

APPPLPNR

2.98

-5.88

-7.16

RRPPPPPI

4.14

-4.14

-5.42

RRRPPPPP

4.42

-3.79

-5.07

Q12446

APPPPPAF

4.08

-5.21

-6.49

PPPRRGPA

4.44

-5.19

-6.47

PPPPRASR

4.48

-5.01

-6.29

P38266

MPPPKPFR

3.51

-5.97

-7.25

QPPPKPFR

3.57

-6.00

-7.28

LPPPKPFR

3.60

-5.87

-7.15

P40483

SKPSVPPR

5.22

-4.87

-6.15

PSVPPRNY

6.30

-1.71

-2.99

APASKPSV

7.40

-2.69

-3.97

P07244

EMPGMYPP

4.84

-6.06

-7.34

SEMPGMYP

7.33

-2.58

-3.86

PGMYPPGH

8.40

-2.19

-3.47

P40563

APPPVPKK

4.11

-5.44

-6.72

PPVPKKPS

5.57

-3.14

-4.42

VNPGQLPP

5.85

-4.29

-5.57

Q07533

MNNPLPPL

4.36

-3.17

-4.45

PNLPLASH

5.31

-1.89

-3.17

IPPVPSRY

5.45

-2.62

-3.90

P53901

AMRPIPPL

4.65

-3.79

-5.07

MRPIPPLP

5.10

-3.61

-4.89

NDPIILPP

5.52

-4.09

-5.37

P37254

VGPGPGNP

6.69

-2.26

-3.54

PGPGNPNN

8.07

-2.83

-4.11

Q12489

SRPSAPPP

5.53

-4.61

-5.89

YSRPSAPP

7.87

-1.27

-2.55

PSAPPPGY

7.99

-2.03

-3.31

 


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