ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1ZX6-7.PDB
Scoring matrix: PIN3_1ZX6-7_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AGAAAAAA
Foldx wt ligand score: 12.34
Foldx random average score for Saccharomyces cerevisiae: 9.844

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1501079
Proteins after disorder filtering: 4707
 Total fragments: 86115
Proteins after pattern filtering: 2213
 Total fragments: 13347
Proteins after MINT filtering: 26
 Total fragments: 440


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AGAAAAAA

12.34

1.49

0.00

Best peptides

IPPIRPLW

0.00

-4.19

-5.68

         
Interactors      
Q06604

EKGPRMPS

6.64

-2.73

-4.22

EEKPLLPT

7.40

-2.06

-3.55

PPPLPTRR

7.54

-3.80

-5.29

P24583

PLPPQPRK

6.94

-3.23

-4.72

ANAPLPPQ

7.52

-2.59

-4.08

PPQPRKHD

7.73

-3.21

-4.70

P38260

GPDDPTLM

8.14

-1.56

-3.05

Q04322

TSPPLPPR

6.88

-2.64

-4.13

PPTLPPRR

7.59

-3.80

-5.29

QAPLDRPQ

7.71

-1.75

-3.24

Q12168

GPPPLPPR

7.14

-2.45

-3.94

PPPLPPRA

7.30

-4.29

-5.78

QHPVPKPN

7.47

-2.42

-3.91

P15891

QPPLPSRN

6.66

-3.67

-5.16

DEPEGEPD

7.03

-0.91

-2.40

PPPPRRAT

7.20

-2.51

-4.00

Q12344

TSPKLPPR

7.01

-3.17

-4.66

SSPPLPPR

7.15

-2.37

-3.86

SPPLPPRQ

7.76

-3.49

-4.98

P39521

HVPDRPPS

7.10

-1.47

-2.96

VPDRPPSQ

7.45

-3.38

-4.87

VQTPHVPD

8.17

-2.54

-4.03

P40325

RPPPRPQQ

4.75

-2.95

-4.44

RPHQRPST

5.77

-2.78

-4.27

YVQPGDPR

5.86

-1.61

-3.10

Q08601

APPPGPPP

6.70

-2.35

-3.84

PPGPPPMA

6.95

-4.45

-5.94

YAPPPGPP

7.33

-2.21

-3.70

Q12532

PFKPYING

9.29

-1.77

-3.26

P19812

EPRPRRIP

6.15

-3.38

-4.87

PRPRRIPP

6.54

-3.24

-4.73

HSPIFRPG

7.25

-1.60

-3.09

Q12412

DPNHRPPS

5.64

-3.23

-4.72

RPPQPPPA

6.77

-2.84

-4.33

YDPNHRPP

7.10

-2.87

-4.36

Q08412

DVPPQLPT

7.02

-0.84

-2.33

PLPPEPLD

7.08

-2.10

-3.59

KWQPLPPE

7.41

-2.88

-4.37

P53118

VENPHDLP

7.45

-3.06

-4.55

NPHDLPSH

8.84

-1.61

-3.10

PHDLPSHL

8.90

-3.34

-4.83

P38216

RPSNPPPS

7.57

-2.52

-4.01

YSRPSNPP

9.02

-0.54

-2.03

QYSRPSNP

9.38

-3.27

-4.76

P53933

RVAPPPLP

6.34

-2.87

-4.36

VSYPGNPT

6.70

-1.96

-3.45

RRPPPPPI

6.77

-3.02

-4.51

Q12446

VPPPPPMR

5.18

-5.39

-6.88

PPPRRGPA

5.26

-3.44

-4.93

RPLPQLPN

6.21

-1.23

-2.72

P38266

ITPPRPPP

4.39

-3.80

-5.29

PQPPQPMQ

5.80

-3.12

-4.61

YPIEPSLD

6.04

-2.78

-4.27

P40483

KPSVPPRN

7.48

-4.24

-5.73

PSVPPRNY

9.61

-2.43

-3.92

KDAPASKP

9.62

-1.29

-2.78

P07244

MPGMYPPG

6.28

-5.27

-6.76

SEMPGMYP

8.96

-1.32

-2.81

P40563

MVNPGQLP

6.01

-4.86

-6.35

RAPPPVPK

7.02

-1.83

-3.32

PTPAGTPN

7.65

-1.28

-2.77

Q07533

IPPVPSRY

5.73

-4.89

-6.38

MNNPLPPL

6.83

-4.48

-5.97

SAPNLPLA

6.87

-1.64

-3.13

P53901

MRPIPPLP

5.92

-5.52

-7.01

DPIILPPT

6.15

-3.12

-4.61

SPKLPPLP

7.03

-4.70

-6.19

P37254

GPGPGNPN

7.91

-0.75

-2.24

Q12489

RPSAPPPG

7.47

-2.32

-3.81

YSRPSAPP

8.86

-1.17

-2.66

 


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