ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1ZX6-29.PDB
Scoring matrix: PIN3_1ZX6-29_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 17.05
Foldx random average score for Saccharomyces cerevisiae: 11.357

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7178
 Total fragments: 1404832
Proteins after disorder filtering: 4030
 Total fragments: 46810
Proteins after pattern filtering: 2006
 Total fragments: 10915
Proteins after MINT filtering: 24
 Total fragments: 322


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

17.05

-1.58

0.00

Best peptides

RRKPMFFRMH

0.00

-12.65

-11.07

         
Interactors      
Q06604

EKPLLPTRPN

6.87

-12.60

-11.02

LLPTRPNKAE

7.89

-10.34

-8.76

KGPRMPSRGR

8.08

-10.80

-9.22

P24583

PLPPQPRKHD

6.28

-8.77

-7.19

ANAPLPPQPR

9.61

-6.68

-5.10

APLPPQPRKH

9.79

-10.01

-8.43

Q04322

TPPTLPPRRI

8.42

-11.51

-9.93

TSPPLPPRAD

8.91

-10.48

-8.90

STPPTLPPRR

9.56

-9.20

-7.62

P19812

PRPRRIPPTD

7.56

-7.75

-6.17

SPIFRPGNIF

9.90

-8.85

-7.27

EPRPRRIPPT

9.94

-6.05

-4.47

P15891

PRRATPEKKP

6.83

-8.24

-6.66

ATPEKKPKEN

8.50

-7.46

-5.88

AAPPPPPRRA

8.65

-10.62

-9.04

Q12344

SSPPLPPRQN

7.47

-11.48

-9.90

PKLPPRGKQR

8.66

-5.32

-3.74

TSPKLPPRGK

9.23

-10.88

-9.30

P39521

QTPHVPDRPP

8.51

-11.82

-10.24

HVPDRPPSQL

9.39

-9.88

-8.30

VPDRPPSQLS

9.55

-7.53

-5.95

P40325

SQPPRPPRPA

5.18

-13.32

-11.74

PRPPPRPQQN

6.82

-7.08

-5.50

SQPRPPPRPQ

7.25

-11.86

-10.28

Q08601

QRPMAPPPNQ

9.82

-7.19

-5.61

PMAPPPNQQY

9.91

-7.50

-5.92

YQRPMAPPPN

10.00

-7.78

-6.20

Q12532

PFKPYINGGD

11.33

-4.32

-2.74

Q12168

IPPPVPNRPG

7.35

-11.92

-10.34

NDDPYFPQFR

7.55

-6.98

-5.40

DDPYFPQFRS

8.95

-8.00

-6.42

Q12412

AYDPNHRPPS

9.22

-7.12

-5.54

PAYDPNHRPP

11.12

-8.02

-6.44

PPPAYDPNHR

11.26

-4.73

-3.15

Q08412

ELPTQPVRKN

7.07

-11.24

-9.66

GKNSRPQQPE

8.83

-8.16

-6.58

DDEDVPPQLP

8.93

-9.25

-7.67

P53118

NPHDLPSHLG

10.03

-7.81

-6.23

ENPHDLPSHL

11.17

-7.40

-5.82

P38216

SRPSNPPPSS

9.84

-7.32

-5.74

YSRPSNPPPS

9.97

-6.15

-4.57

SQYSRPSNPP

10.15

-8.59

-7.01

P53933

RRPPPPPIPS

6.54

-9.83

-8.25

KRVAPPPLPN

6.91

-7.53

-5.95

VRTRRRPPPP

7.95

-7.41

-5.83

Q12446

PFPFPVPQQQ

7.26

-7.28

-5.70

SQPQSNPFPF

7.58

-8.19

-6.61

SLPPLPNQFA

8.05

-8.86

-7.28

P38266

GQPPVPVRMQ

5.06

-13.77

-12.19

KKPPVVPKKK

5.09

-10.41

-8.83

LPPPKPFRHT

5.92

-11.30

-9.72

P40483

SKPSVPPRNY

7.35

-11.87

-10.29

ASKPSVPPRN

9.07

-5.32

-3.74

TKDAPASKPS

10.03

-7.49

-5.91

P07244

EMPGMYPPGH

8.15

-10.40

-8.82

ETSEMPGMYP

9.61

-7.79

-6.21

P40563

APPPVPKKPS

7.27

-9.39

-7.81

KRRAPPPVPK

8.41

-6.89

-5.31

RAPPPVPKKP

8.44

-7.85

-6.27

Q07533

SMPNSPKKPV

7.18

-9.00

-7.42

PLPPLPPLPD

7.46

-9.78

-8.20

KSPKAYPKLP

8.02

-8.10

-6.52

P53901

AMRPIPPLPT

6.27

-11.00

-9.42

PLPPIPTRDD

7.41

-11.94

-10.36

NQPPLPPIPT

8.14

-8.97

-7.39

Q12489

SRPSAPPPGY

9.86

-6.72

-5.14

QSYSRPSAPP

10.83

-8.34

-6.76

 


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