ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1ZX6-21.PDB
Scoring matrix: PIN3_1ZX6-21_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAGGAAAA
Foldx wt ligand score: 12.96
Foldx random average score for Saccharomyces cerevisiae: 12.521

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1986657
Proteins after disorder filtering: 4444
 Total fragments: 69970
Proteins after pattern filtering: 1752
 Total fragments: 4338
Proteins after MINT filtering: 21
 Total fragments: 87


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAGGAAAA

12.96

-0.73

0.00

Best peptides

EKRRGRPMMM

0.00

-4.00

-3.27

         
Interactors      
P39521

QPKPKPAQDN

10.89

-2.78

-2.05

Q06604

EKGPRMPSRG

6.90

-4.60

-3.87

PLLPTRPNKA

6.91

-4.67

-3.94

PPLPTRRDHI

9.05

-2.47

-1.74

P53118

ENPHDLPSHL

11.96

-3.35

-2.62

P40325

YVQPGDPRLG

7.05

-6.95

-6.22

LPWTYPPRFY

9.93

-7.07

-6.34

SRPHQRPSTM

10.37

-3.16

-2.43

P24583

PPQPRKHDKT

8.05

-3.65

-2.92

PLPPQPRKHD

10.61

-4.73

-4.00

P07244

MPGMYPPGHY

11.82

-4.21

-3.48

P53933

VSYPGNPTSR

10.82

-2.45

-1.72

P40563

NSQPQGPSDT

10.71

-2.16

-1.43

NPGQLPPSLE

11.91

-3.33

-2.60

P53901

PPIPTRDDMS

7.17

-3.79

-3.06

DPIILPPTFS

9.60

-4.98

-4.25

PPLPTTSNSN

11.70

-2.68

-1.95

Q12532

PFKPYINGGD

11.47

-2.49

-1.76

P19812

HSPIFRPGNI

10.36

-2.62

-1.89

SPIFRPGNIF

10.93

-4.68

-3.95

RPRRIPPTDE

11.76

-3.76

-3.03

Q04322

TPPTLPPRRI

12.46

-5.91

-5.18

Q12168

PNRPGGTTNR

10.03

-3.81

-3.08

NDDPYFPQFR

10.41

-4.30

-3.57

PPVPNRPGGT

10.74

-2.22

-1.49

P15891

DEPEGEPDVK

10.67

-1.82

-1.09

PPLPSRNVAS

10.92

-3.78

-3.05

TPSPAPAAKI

11.13

-4.23

-3.50

Q12446

RPLPQLPNRN

7.49

-4.25

-3.52

APLPDPPQHN

10.23

-3.25

-2.52

PEIPSTQSAT

10.45

-2.90

-2.17

P37254

GPGPGNPNNG

10.55

-3.00

-2.27

P38260

GGGPDDPTLM

11.35

-4.09

-3.36

Q08412

IELPTQPVRK

8.56

-3.98

-3.25

ELPTQPVRKN

8.90

-7.77

-7.04

PQLPTRTKSG

9.94

-3.06

-2.33

Q12344

PLPPRQNVAT

11.64

-4.40

-3.67

SSPPLPPRQN

11.77

-5.87

-5.14

Q07533

PPLPDLDNMR

9.79

-4.83

-4.10

NSAPNLPLAS

10.21

-3.73

-3.00

VSSPKSPKAY

10.21

-3.60

-2.87

P38266

PLKPGQKTYT

7.65

-4.29

-3.56

KKPPVVPKKK

7.68

-4.55

-3.82

KVPPVVPKKN

8.84

-5.31

-4.58

 


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