ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: PIN3_1YNZ-9.PDB
Scoring matrix: PIN3_1YNZ-9_mat
Uniprot code: Q06449
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAA
Foldx wt ligand score: 15.0
Foldx random average score for Saccharomyces cerevisiae: 10.317

Available information for Q06449 in MINT (Nov 2008):
Nš of interacting proteins: 38
 Proteins belonging to other specie: 0
Nš of interactions described: 44
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3214721
Proteins after random average filtering: 7179
 Total fragments: 1464837
Proteins after disorder filtering: 4538
 Total fragments: 66180
Proteins after pattern filtering: 2026
 Total fragments: 9124
Proteins after MINT filtering: 24
 Total fragments: 259


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAA

15.00

0.64

0.00

Best peptides

RRPMMPMK

0.00

-6.29

-6.93

         
Interactors      
Q06604

LLPTRPNK

5.65

-4.17

-4.81

KGPRMPSR

7.29

-4.55

-5.19

KPLLPTRP

7.31

-8.26

-8.90

P24583

PLPPQPRK

6.72

-5.30

-5.94

LPPQPRKH

7.08

-7.59

-8.23

PPQPRKHD

10.17

-2.58

-3.22

P38260

GPDDPTLM

9.78

-6.37

-7.01

Q04322

APLDRPQL

8.11

-2.55

-3.19

SPPLPPRA

9.02

-6.92

-7.56

PPTLPPRR

9.14

-8.11

-8.75

P19812

PRPRRIPP

7.05

-3.26

-3.90

HSPIFRPG

8.27

-3.31

-3.95

EPRPRRIP

8.37

-4.63

-5.27

P15891

FTPSKSPA

8.46

-1.39

-2.03

TPEKKPKE

8.52

-4.46

-5.10

ATPEKKPK

8.54

-1.32

-1.96

Q12344

SPPLPPRQ

9.22

-7.44

-8.08

SPKLPPRG

9.32

-7.34

-7.98

TTSSPPLP

9.58

-3.40

-4.04

P39521

HVPDRPPS

7.13

-3.84

-4.48

TPHVPDRP

9.21

-6.21

-6.85

PKPKPAQD

10.00

-4.50

-5.14

P40325

RPSTMPAT

6.10

-4.24

-4.88

RPPPRPQQ

6.63

-5.46

-6.10

QPPRPPRP

6.70

-7.99

-8.63

Q08601

NRPVYPPP

7.42

-3.52

-4.16

QRPMAPPP

8.55

-4.25

-4.89

YQRPMAPP

9.03

-3.79

-4.43

Q12168

NRGPPPLP

8.74

-4.09

-4.73

PPPVPNRP

8.90

-7.10

-7.74

PPPLPPRA

8.94

-8.20

-8.84

Q12412

RPPQPPPA

7.53

-6.15

-6.79

YDPNHRPP

9.51

-1.47

-2.11

PPAYDPNH

9.72

-4.05

-4.69

Q08412

LPTQPVRK

6.19

-7.80

-8.44

KNSRPQQP

8.17

-4.79

-5.43

ELPTQPVR

8.24

-3.56

-4.20

P53118

NPHDLPSH

9.10

-3.63

-4.27

P38216

RPSNPPPS

7.89

-6.17

-6.81

SRPSNPPP

9.55

-1.68

-2.32

P53933

RVAPPPLP

6.81

-5.92

-6.56

RPPPPPIP

7.03

-7.38

-8.02

RRPPPPPI

7.46

-5.15

-5.79

Q12446

RPLPQLPN

7.62

-1.78

-2.42

NPFPFPIP

7.74

-4.71

-5.35

PPPRRGPA

7.76

-4.77

-5.41

P38266

PPPKPFRH

6.53

-7.85

-8.49

LPPPKPFR

7.21

-6.46

-7.10

PPLKPGQK

7.34

-6.59

-7.23

P40483

KPSVPPRN

6.78

-7.55

-8.19

KDAPASKP

9.76

-2.88

-3.52

P07244

MPGMYPPG

7.84

-6.55

-7.19

SEMPGMYP

9.62

-4.13

-4.77

EMPGMYPP

10.10

-1.18

-1.82

P40563

RRAPPPVP

7.67

-4.78

-5.42

RAPPPVPK

8.55

-4.53

-5.17

TPKVPERP

8.72

-6.10

-6.74

Q07533

IPPVPSRY

6.95

-7.05

-7.69

LPPLPPLP

7.52

-8.49

-9.13

KSPKAYPK

7.97

-3.31

-3.95

P53901

MRPIPPLP

5.98

-6.02

-6.66

LPPIPTRD

7.09

-7.91

-8.55

RPIPPLPT

8.88

-5.43

-6.07

Q12489

RPSAPPPG

9.11

-5.16

-5.80

 


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